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Biodegradable poly(L-lactide) and polycaprolactone block copolymer networks

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Biodegradable poly(L-lactide) and polycaprolactone block copolymer networks

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Nombre: Escobar;Salmerón;Gómez ...
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dc.contributor.author Escobar Ivirico, Jorge Luis es_ES
dc.contributor.author Salmerón Sánchez, Manuel es_ES
dc.contributor.author Gómez Ribelles, José Luís es_ES
dc.contributor.author Monleón Pradas, Manuel es_ES
dc.date.accessioned 2016-05-17T09:15:03Z
dc.date.available 2016-05-17T09:15:03Z
dc.date.issued 2011
dc.identifier.issn 0959-8103
dc.identifier.uri http://hdl.handle.net/10251/64209
dc.description.abstract New biodegradable block copolymer networks were synthesized from methacrylate-terminated poly(L-lactide) (mLA) and polycaprolactone (mCL) macromers. This allowed the realization of a series of materials in which the macromer ratio can be used to tailor the physical and mechanical properties of the materials. The synthesis of the macromers was characterized using Fourier transform infrared (FTIR) spectroscopy and 1H NMR spectroscopy. Poly(mCL) and poly(mLA) networks were prepared by photopolymerization of the macromers, and copolymers were also prepared from the two macromers in various proportions. The phase microstructure of the new systems and the network architecture were investigated using differential scanning calorimetry, FTIR spectroscopy, dynamic mechanical analysis and thermogravimetry studies. Ideal structure, compatible with the experiments results, for biodegradable poly(L-lactide) and polycaprolactone block copolymer networks. Copyright © 2010 Society of Chemical Industry. es_ES
dc.description.sponsorship The authors acknowledge the support of the Spanish Science & Innovation Ministry through project MAT2008-06434. JLEI acknowledge the support of Spanish Science & Innovation Ministry through the "Campus de Excelencia Internacional" program consistent with Polytechnic University of Valencia. The authors also acknowledge the support of CIBER-BBN which is an initiative funded by the VI National R&D&D&i Plan 2008 - 2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund and the funding by the Centro de Investigacion Principe Felipe in the field of regenerative medicine through the collaboration agreement from the Conselleria de Sanidad (Generalitat Valenciana) and the Instituto de Salud Carlos III (Ministry of Science and Innovation). en_EN
dc.language Inglés es_ES
dc.publisher Wiley es_ES
dc.relation.ispartof Polymer International es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Biodegradable es_ES
dc.subject Block copolymer es_ES
dc.subject Poly(L-lactide) es_ES
dc.subject Polycaprolactone es_ES
dc.subject Polyester es_ES
dc.subject Polymer network es_ES
dc.subject Biodegradable block copolymers es_ES
dc.subject Copolymer networks es_ES
dc.subject FTIR spectroscopy es_ES
dc.subject H NMR spectroscopy es_ES
dc.subject Macromer ratio es_ES
dc.subject Macromers es_ES
dc.subject New system es_ES
dc.subject Physical and mechanical properties es_ES
dc.subject Poly (l-lactide) es_ES
dc.subject Thermogravimetry es_ES
dc.subject Biodegradable polymers es_ES
dc.subject Block copolymers es_ES
dc.subject Copolymerization es_ES
dc.subject Differential scanning calorimetry es_ES
dc.subject Dynamic analysis es_ES
dc.subject Dynamic mechanical analysis es_ES
dc.subject Fourier transform infrared spectroscopy es_ES
dc.subject Fourier transforms es_ES
dc.subject Materials properties es_ES
dc.subject Mechanical properties es_ES
dc.subject Network architecture es_ES
dc.subject Nuclear magnetic resonance spectroscopy es_ES
dc.subject Photopolymerization es_ES
dc.subject Plastic products es_ES
dc.subject Thermogravimetric analysis es_ES
dc.subject Organic polymers es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.subject.classification FISICA APLICADA es_ES
dc.title Biodegradable poly(L-lactide) and polycaprolactone block copolymer networks es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1002/pi.2938
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MAT2008-06434/ES/MATERIALES PARA REGENERACION NEURAL Y ANGIOGENESIS EN EL SISTEMA NERVIOSO CENTRAL/ es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.contributor.affiliation Universitat Politècnica de València. Centro de Biomateriales e Ingeniería Tisular - Centre de Biomaterials i Enginyeria Tissular es_ES
dc.description.bibliographicCitation Escobar Ivirico, JL.; Salmerón Sánchez, M.; Gómez Ribelles, JL.; Monleón Pradas, M. (2011). Biodegradable poly(L-lactide) and polycaprolactone block copolymer networks. Polymer International. 60(2):264-270. https://doi.org/10.1002/pi.2938 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1002/pi.2938 es_ES
dc.description.upvformatpinicio 264 es_ES
dc.description.upvformatpfin 270 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 60 es_ES
dc.description.issue 2 es_ES
dc.relation.senia 191788 es_ES
dc.contributor.funder Ministerio de Ciencia e Innovación es_ES
dc.contributor.funder Centro de Investigación Príncipe Felipe es_ES
dc.contributor.funder Instituto de Salud Carlos III es_ES
dc.description.references Pitt, C. G., Chasalow, F. I., Hibionada, Y. M., Klimas, D. M., & Schindler, A. (1981). Aliphatic polyesters. I. The degradation of poly(ϵ-caprolactone)in vivo. Journal of Applied Polymer Science, 26(11), 3779-3787. doi:10.1002/app.1981.070261124 es_ES
dc.description.references Engelberg, I., & Kohn, J. (1991). Physico-mechanical properties of degradable polymers used in medical applications: A comparative study. Biomaterials, 12(3), 292-304. doi:10.1016/0142-9612(91)90037-b es_ES
dc.description.references Ali, S. A. M., Zhong, S.-P., Doherty, P. J., & Williams, D. F. (1993). Mechanisms of polymer degradation in implantable devices. Biomaterials, 14(9), 648-656. doi:10.1016/0142-9612(93)90063-8 es_ES
dc.description.references Edlund, U., & Albertsson, A.-C. (2000). Morphology engineering of a novel poly(L-lactide)/poly(1,5-dioxepan-2-one) microsphere system for controlled drug delivery. Journal of Polymer Science Part A: Polymer Chemistry, 38(5), 786-796. doi:10.1002/(sici)1099-0518(20000301)38:5<786::aid-pola2>3.0.co;2-7 es_ES
dc.description.references Ajji, A., & Renaud, M. C. (1991). Mechanical properties of oriented poly(vinyl chloride)–poly(caprolactone) blends. Journal of Applied Polymer Science, 42(2), 335-345. doi:10.1002/app.1991.070420205 es_ES
dc.description.references Chiu, S.-C., & Smith, T. G. (1984). Compatibility of poly(ε-caprolactone) (PCL) and poly(styrene-co-acrylonitrile) (SAN) blends. II. The influence of the AN content in SAN copolymer upon blend compatibility. Journal of Applied Polymer Science, 29(5), 1797-1814. doi:10.1002/app.1984.070290532 es_ES
dc.description.references Edlund, U., & Albertsson, A.-C. (1999). Novel drug delivery microspheres from poly(1,5-dioxepan-2-one-co-L-lactide). Journal of Polymer Science Part A: Polymer Chemistry, 37(12), 1877-1884. doi:10.1002/(sici)1099-0518(19990615)37:12<1877::aid-pola17>3.0.co;2-4 es_ES
dc.description.references EDLUND, U., & ALBERTSSON, A.-C. (2000). Microspheres from Poly(D,L-lactide)/ Poly(1,5-dioxepan-2-one) Miscible Blends for Controlled Drug Delivery. Journal of Bioactive and Compatible Polymers, 15(3), 214-229. doi:10.1106/me8a-mubn-4lfh-p6xq es_ES
dc.description.references Lou, C.-W., Yao, C.-H., Chen, Y.-S., Hsieh, T.-C., Lin, J.-H., & Hsing, W.-H. (2008). Manufacturing and Properties of PLA Absorbable Surgical Suture. Textile Research Journal, 78(11), 958-965. doi:10.1177/0040517507087856 es_ES
dc.description.references Zurita, R., Puiggalí, J., & Rodríguez-Galán, A. (2006). Loading and Release of Ibuprofen in Multi- and Monofilament Surgical Sutures. Macromolecular Bioscience, 6(9), 767-775. doi:10.1002/mabi.200600084 es_ES
dc.description.references Lim Soo, P., Cho, J., Grant, J., Ho, E., Piquette-Miller, M., & Allen, C. (2008). Drug release mechanism of paclitaxel from a chitosan–lipid implant system: Effect of swelling, degradation and morphology. European Journal of Pharmaceutics and Biopharmaceutics, 69(1), 149-157. doi:10.1016/j.ejpb.2007.11.003 es_ES
dc.description.references DEPAN, D., KUMAR, A., & SINGH, R. (2009). Cell proliferation and controlled drug release studies of nanohybrids based on chitosan-g-lactic acid and montmorillonite. Acta Biomaterialia, 5(1), 93-100. doi:10.1016/j.actbio.2008.08.007 es_ES
dc.description.references Kalb, B., & Pennings, A. J. (1980). General crystallization behaviour of poly(l-lactic acid). Polymer, 21(6), 607-612. doi:10.1016/0032-3861(80)90315-8 es_ES
dc.description.references Jamshidi, K., Hyon, S.-H., & Ikada, Y. (1988). Thermal characterization of polylactides. Polymer, 29(12), 2229-2234. doi:10.1016/0032-3861(88)90116-4 es_ES
dc.description.references Brode, G. L., & Koleske, J. V. (1972). Lactone Polymerization and Polymer Properties. Journal of Macromolecular Science: Part A - Chemistry, 6(6), 1109-1144. doi:10.1080/10601327208056888 es_ES
dc.description.references Wu, D., Zhang, Y., Zhang, M., & Zhou, W. (2008). Phase behavior and its viscoelastic response of polylactide/poly(ε-caprolactone) blend. European Polymer Journal, 44(7), 2171-2183. doi:10.1016/j.eurpolymj.2008.04.023 es_ES
dc.description.references Todo, M., Park, S.-D., Takayama, T., & Arakawa, K. (2007). Fracture micromechanisms of bioabsorbable PLLA/PCL polymer blends. Engineering Fracture Mechanics, 74(12), 1872-1883. doi:10.1016/j.engfracmech.2006.05.021 es_ES
dc.description.references Yu, Z., Yin, J., Yan, S., Xie, Y., Ma, J., & Chen, X. (2007). Biodegradable poly(l-lactide)/poly(ɛ-caprolactone)-modified montmorillonite nanocomposites: Preparation and characterization. Polymer, 48(21), 6439-6447. doi:10.1016/j.polymer.2007.07.024 es_ES
dc.description.references Broz, M. (2003). Structure and mechanical properties of poly(?,?-lactic acid)/poly(ɛ-caprolactone) blends. Biomaterials, 24(23), 4181-4190. doi:10.1016/s0142-9612(03)00314-4 es_ES
dc.description.references Zhang, L., Xiong, C., & Deng, X. (1995). Biodegradable polyester blends for biomedical application. Journal of Applied Polymer Science, 56(1), 103-112. doi:10.1002/app.1995.070560114 es_ES
dc.description.references Huang, M.-H., Li, S., & Vert, M. (2004). Synthesis and degradation of PLA–PCL–PLA triblock copolymer prepared by successive polymerization of ε-caprolactone and dl-lactide. Polymer, 45(26), 8675-8681. doi:10.1016/j.polymer.2004.10.054 es_ES
dc.description.references Feng (S. T. Voong), X. D., Song, C. X., & Chen, W. Y. (1983). Synthesis and evaluation of biodegradable block copolymers of ɛ-caprolactone and DL-lactide. Journal of Polymer Science: Polymer Letters Edition, 21(8), 593-600. doi:10.1002/pol.1983.130210802 es_ES
dc.description.references Ye, W.-P., & Chien, Y. W. (1996). Dual-controlled drug delivery across biodegradable copolymer. II. Delivery kinetics of levonorgestrel and estradiol from (matrix/matrix) laminate drug delivery system. Journal of Controlled Release, 41(3), 259-269. doi:10.1016/0168-3659(96)01330-2 es_ES
dc.description.references Lang, M., Wong, R. P., & Chu, C.-C. (2002). Synthesis and structural analysis of functionalized poly (?-caprolactone)-based three-arm star polymers. Journal of Polymer Science Part A: Polymer Chemistry, 40(8), 1127-1141. doi:10.1002/pola.10171 es_ES
dc.description.references Lang, M., & Chu, C.-C. (2002). Functionalized multiarm poly(?-caprolactone)s: Synthesis, structure analysis, and network formation. Journal of Applied Polymer Science, 86(9), 2296-2306. doi:10.1002/app.11221 es_ES
dc.description.references Burdick, J. A., Philpott, L. M., & Anseth, K. S. (2001). Synthesis and characterization of tetrafunctional lactic acid oligomers: A potentialin situ forming degradable orthopaedic biomaterial. Journal of Polymer Science Part A: Polymer Chemistry, 39(5), 683-692. doi:10.1002/1099-0518(20010301)39:5<683::aid-pola1040>3.0.co;2-z es_ES
dc.description.references Storey, R. F., Wiggins, J. S., Mauritz, K. A., & Puckett, A. D. (1993). Bioabsorbable composites. I: Fundamental design considerations using free radically crosslinkable matrices. Polymer Composites, 14(1), 7-16. doi:10.1002/pc.750140103 es_ES
dc.description.references Han, Y.-K., Edelman, P. G., & Huang, S. J. (1988). Synthesis and Characterization of Crosslinked Polymers for Biomedical Composites. Journal of Macromolecular Science: Part A - Chemistry, 25(5-7), 847-869. doi:10.1080/00222338808053402 es_ES
dc.description.references Turunen, M. P. K., Korhonen, H., Tuominen, J., & Seppälä, J. V. (2001). Synthesis, characterization and crosslinking of functional star-shaped poly(ε-caprolactone). Polymer International, 51(1), 92-100. doi:10.1002/pi.805 es_ES
dc.description.references Sawhney, A. S., Pathak, C. P., & Hubbell, J. A. (1993). Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(.alpha.-hydroxy acid) diacrylate macromers. Macromolecules, 26(4), 581-587. doi:10.1021/ma00056a005 es_ES
dc.description.references Storey, R. F., Warren, S. C., Allison, C. J., Wiggins, J. S., & Puckett, A. . (1993). Synthesis of bioabsorbable networks from methacrylate-endcapped polyesters. Polymer, 34(20), 4365-4372. doi:10.1016/0032-3861(93)90203-m es_ES
dc.description.references Storey, R. F., Warren, S. C., Allison, C. ., & Puckett, A. . (1997). Methacrylate-endcapped poly(d,l-lactide-co-trimethylene carbonate) oligomers. Network formation by thermal free-radical curing. Polymer, 38(26), 6295-6301. doi:10.1016/s0032-3861(97)00208-5 es_ES
dc.description.references Davis, K. A., Burdick, J. A., & Anseth, K. S. (2003). Photoinitiated crosslinked degradable copolymer networks for tissue engineering applications. Biomaterials, 24(14), 2485-2495. doi:10.1016/s0142-9612(02)00582-3 es_ES
dc.description.references Takao, A., Fusae, M., & Yu, N. (1994). Preparation of cross-linked aliphatic polyester and application to thermo-responsive material. Journal of Controlled Release, 32(1), 87-96. doi:10.1016/0168-3659(94)90228-3 es_ES
dc.description.references Mizutani, M., & Matsuda, T. (2002). Liquid acrylate-endcapped biodegradable poly(?-caprolactone-co-trimethylene carbonate). I. Preparation and visible light-induced photocuring characteristics. Journal of Biomedical Materials Research, 62(3), 387-394. doi:10.1002/jbm.10294 es_ES
dc.description.references Domb, A. J., Mathiowitz, E., Ron, E., Giannos, S., & Langer, R. (1991). Polyanhydrides. IV. Unsaturated and crosslinked polyanhydrides. Journal of Polymer Science Part A: Polymer Chemistry, 29(4), 571-579. doi:10.1002/pola.1991.080290413 es_ES
dc.description.references Anseth, K. S., Shastri, V. R., & Langer, R. (1999). Photopolymerizable degradable polyanhydrides with osteocompatibility. Nature Biotechnology, 17(2), 156-159. doi:10.1038/6152 es_ES
dc.description.references Kim, B. S., Hrkach, J. S., & Langer, R. (2000). Synthesis and characterization of novel degradable photocrosslinked poly(ether-anhydride) networks. Journal of Polymer Science Part A: Polymer Chemistry, 38(8), 1277-1282. doi:10.1002/(sici)1099-0518(20000415)38:8<1277::aid-pola11>3.0.co;2-s es_ES
dc.description.references Korhonen, H., & Seppälä, J. V. (2001). Synthesis of poly(ester-anhydride)s based on poly(ϵ-caprolactone) prepolymer. Journal of Applied Polymer Science, 81(1), 176-185. doi:10.1002/app.1427 es_ES
dc.description.references Escobar Ivirico, J. L., Salmerón Sánchez, M., Sabater i Serra, R., Meseguer Dueñas, J. M., Gómez Ribelles, J. L., & Monleón Pradas, M. (2006). Structure and Properties of Poly(ɛ-caprolactone) Networks with Modulated Water Uptake. Macromolecular Chemistry and Physics, 207(23), 2195-2205. doi:10.1002/macp.200600399 es_ES
dc.description.references Sabater i Serra, R., Escobar Ivirico, J. L., Meseguer Dueñas, J. M., Andrio Balado, A., Gómez Ribelles, J. L., & Salmerón Sánchez, M. (2007). Dielectric relaxation spectrum of poly (ε-caprolactone) networks hydrophilized by copolymerization with 2-hydroxyethyl acrylate. The European Physical Journal E, 22(4), 293-302. doi:10.1140/epje/e2007-00036-7 es_ES
dc.description.references Sabater i Serra, R., Escobar Ivirico, J. L., Meseguer Dueñas, J. M., Balado, A. A., Gómez Ribelles, J. L., & Salmerón Sánchez, M. (2009). Segmental dynamics in poly(ε-caprolactone)/poly(L-lactide) copolymer networks. Journal of Polymer Science Part B: Polymer Physics, 47(2), 183-193. doi:10.1002/polb.21629 es_ES
dc.description.references Escobar Ivirico, J. L., Salmerón-Sánchez, M., Gómez Ribelles, J. L., & Monleón Pradas, M. (2009). Poly(l-lactide) networks with tailored water sorption. Colloid and Polymer Science, 287(6), 671-681. doi:10.1007/s00396-009-2026-z es_ES


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