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Carbon-11 Radiolabelling of Organosulfur Compounds: 11C Synthesis of the Progesterone Receptor Agonist Tanaproget

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Carbon-11 Radiolabelling of Organosulfur Compounds: 11C Synthesis of the Progesterone Receptor Agonist Tanaproget

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Haywood, T.; Kealey, S.; Sánchez-Cabezas, S.; Hall, JJ.; Allott, L.; Smith, G.; Plisson, C.... (2015). Carbon-11 Radiolabelling of Organosulfur Compounds: 11C Synthesis of the Progesterone Receptor Agonist Tanaproget. Chemistry - A European Journal. 21(25):9034-9038. doi:10.1002/chem.201501089

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Title: Carbon-11 Radiolabelling of Organosulfur Compounds: 11C Synthesis of the Progesterone Receptor Agonist Tanaproget
Author: Haywood, Tom Kealey, Steven Sánchez-Cabezas, Santiago Hall, James J. Allott, Louis Smith, Graham Plisson, Christophe Miller, Philip W.
Issued date:
Abstract:
[EN] Herein a new 11C radiolabelling strategy for the fast and efficient synthesis of thioureas and related derivatives using the novel synthon, 11CS2, is reported. This approach has enabled the facile labelling of a potent ...[+]
Copyrigths: Cerrado
Source:
Chemistry - A European Journal. (issn: 0947-6539 )
DOI: 10.1002/chem.201501089
Publisher:
Wiley
Publisher version: http://dx.doi.org/10.1002/chem.201501089
Project ID:
EPSRC/EP/L025140/1
Royal Society/RG110449
Thanks:
We are grateful to the EPSRC (grant no. EP/L025140/1), The Royal Society (grant no. RG110449) and to the Imperial College-EPSRC Kick-Start programme for supporting this work.
Type: Artículo

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