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dc.contributor.author | Barat Baviera, José Manuel | es_ES |
dc.contributor.author | Pérez-Esteve, Édgar | es_ES |
dc.contributor.author | Bernardos Bau, Andrea | es_ES |
dc.contributor.author | Martínez-Máñez, Ramón | es_ES |
dc.contributor.editor | 11th International Congress on Engineering and Food (ICEF 11) | es_ES |
dc.date.accessioned | 2016-12-19T14:15:54Z | |
dc.date.available | 2016-12-19T14:15:54Z | |
dc.date.issued | 2011 | |
dc.identifier.issn | 2211-601X | |
dc.identifier.uri | http://hdl.handle.net/10251/75377 | |
dc.description.abstract | [EN] Folic acid deficiency causes serious disorders in humans and supplementation has numerous health benefits. However, there is initial evidence that suggest a negative impact of an increased exposure to folic with respect to certain developmental and degenerative disorders. In this line, controlled release of folic acid by using mesoporous silica materials, MCM-41, has been studied as an alternative to direct supplementation. For this purpose, various mesoporous solids MCM-41 loaded with folic acid (S1) and functionalized with 3-[2-(2-aminoethylamino)ethylamino]propyl-trimethoxysilane (S2) acting as "gate" have been tested. The results show that at pH 2 a strongly hindered vitamin release is observed, whereas at pH 7.5 a controlled delivery is found. Based on the obtained results of this study, folic acid controlled release could be feasible during a period of 5h using a sensitive to pH gate, and this might reduce traditional fortification negative effects, while nutritional benefits are maintained | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.ispartof | Procedia Food Science | es_ES |
dc.rights | Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) | es_ES |
dc.subject | Folic acid | es_ES |
dc.subject | Control release | es_ES |
dc.subject | Mesoporous material | es_ES |
dc.subject | Bioavailability | es_ES |
dc.subject | Molecular gates | es_ES |
dc.subject.classification | QUIMICA INORGANICA | es_ES |
dc.subject.classification | TECNOLOGIA DE ALIMENTOS | es_ES |
dc.title | Nutritional effects of folic acid controlled release from mesoporous materials | es_ES |
dc.type | Artículo | es_ES |
dc.type | Comunicación en congreso | es_ES |
dc.identifier.doi | 10.1016/j.profoo.2011.09.268 | |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Tecnología de Alimentos - Departament de Tecnologia d'Aliments | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Química - Departament de Química | es_ES |
dc.description.bibliographicCitation | Barat Baviera, JM.; Pérez-Esteve, É.; Bernardos Bau, A.; Martínez-Máñez, R. (2011). Nutritional effects of folic acid controlled release from mesoporous materials. Procedia Food Science. 1:1828-1832. doi:10.1016/j.profoo.2011.09.268 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.conferencename | 11th International Congress on Engineering and Food (ICEF11) | es_ES |
dc.relation.conferencedate | MAY 22-26, 2011 | es_ES |
dc.relation.conferenceplace | Athens, GREECE | es_ES |
dc.relation.publisherversion | https://dx.doi.org/10.1016/j.profoo.2011.09.268 | es_ES |
dc.description.upvformatpinicio | 1828 | es_ES |
dc.description.upvformatpfin | 1832 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 1 | es_ES |
dc.relation.senia | 207823 | es_ES |