- -

miRNA detection methods and clinical implications in lung cancer

RiuNet: Repositorio Institucional de la Universidad Politécnica de Valencia

Compartir/Enviar a

Citas

Estadísticas

  • Estadisticas de Uso

miRNA detection methods and clinical implications in lung cancer

Mostrar el registro completo del ítem

Usó, M.; Jantus Lewintre, E.; Sirera Pérez, R.; Bremnes, RM.; Camps, C. (2014). miRNA detection methods and clinical implications in lung cancer. Future Oncology. 10(14):2279-2292. https://doi.org/10.2217/FON.14.93

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/78936

Ficheros en el ítem

Thumbnail
Nombre: Uso, Jantus, Sirera, ...
Tamaño: 431.0Kb
Formato: PDF
Descripción: Versión del Autor.
Abrir/Preview
[Cerrado]
Nombre: Sirera;Jantus-Lewintre ...
Tamaño: 1.817Mb
Formato: PDF
Descripción: Versión editorial
Solicitar una copia al autor

Metadatos del ítem

Título: miRNA detection methods and clinical implications in lung cancer
Autor: Usó, Marta Jantus Lewintre, Eloisa Sirera Pérez, Rafael Bremnes, Roy M. Camps, Carlos
Entidad UPV: Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural
Fecha difusión:
Resumen:
[EN] Lung cancer is the leading cause of cancer death worldwide. Therefore, advances in the diagnosis and treatment of the disease are urgently needed. miRNAs are a family of small, noncoding RNAs that regulate gene ...[+]
Palabras clave: Biomarker , Diagnosis , Lung cancer , miRNA , miRNA profiling , Prognosis
Derechos de uso: Reserva de todos los derechos
Fuente:
Future Oncology. (issn: 1479-6694 ) (eissn: 1744-8301 )
DOI: 10.2217/FON.14.93
Editorial:
Future Medicine
Versión del editor: http://dx.doi.org/10.2217/FON.14.93
Código del Proyecto:
info:eu-repo/grantAgreement/MICINN//TRA2009_0132/ES/Micro ARNs con expresión diferencial en cáncer de pulmón no microcítico: Control sobre la angiogénesis/
info:eu-repo/grantAgreement/MINECO//RD12%2F0036%2F0025/ES/Cáncer/
Agradecimientos:
This study was partially supported by a grant from the Ministerio de Ciencia e Inovacion de Espana (TRA09-0132), Beca Roche en Onco-Hematologia 2009 and Red Tematica de Investigacion Cooperativa en Cancer (RD12/0036/0025). ...[+]
Tipo: Artículo

References

Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman, D. (2011). Global cancer statistics. CA: A Cancer Journal for Clinicians, 61(2), 69-90. doi:10.3322/caac.20107

Herbst, R. S., Heymach, J. V., & Lippman, S. M. (2008). Lung Cancer. New England Journal of Medicine, 359(13), 1367-1380. doi:10.1056/nejmra0802714

Ferlay, J., Parkin, D. M., & Steliarova-Foucher, E. (2010). Estimates of cancer incidence and mortality in Europe in 2008. European Journal of Cancer, 46(4), 765-781. doi:10.1016/j.ejca.2009.12.014 [+]
Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman, D. (2011). Global cancer statistics. CA: A Cancer Journal for Clinicians, 61(2), 69-90. doi:10.3322/caac.20107

Herbst, R. S., Heymach, J. V., & Lippman, S. M. (2008). Lung Cancer. New England Journal of Medicine, 359(13), 1367-1380. doi:10.1056/nejmra0802714

Ferlay, J., Parkin, D. M., & Steliarova-Foucher, E. (2010). Estimates of cancer incidence and mortality in Europe in 2008. European Journal of Cancer, 46(4), 765-781. doi:10.1016/j.ejca.2009.12.014

Goldstraw, P., Crowley, J., Chansky, K., Giroux, D. J., Groome, P. A., Rami-Porta, R., … Sobin, L. (2007). The IASLC Lung Cancer Staging Project: Proposals for the Revision of the TNM Stage Groupings in the Forthcoming (Seventh) Edition of the TNM Classification of Malignant Tumours. Journal of Thoracic Oncology, 2(8), 706-714. doi:10.1097/jto.0b013e31812f3c1a

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75(5), 843-854. doi:10.1016/0092-8674(93)90529-y

Winter, J., Jung, S., Keller, S., Gregory, R. I., & Diederichs, S. (2009). Many roads to maturity: microRNA biogenesis pathways and their regulation. Nature Cell Biology, 11(3), 228-234. doi:10.1038/ncb0309-228

Lai, E. C. (2002). Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation. Nature Genetics, 30(4), 363-364. doi:10.1038/ng865

Stark, A., Brennecke, J., Bushati, N., Russell, R. B., & Cohen, S. M. (2005). Animal MicroRNAs Confer Robustness to Gene Expression and Have a Significant Impact on 3′UTR Evolution. Cell, 123(6), 1133-1146. doi:10.1016/j.cell.2005.11.023

Zhang, B., Pan, X., Cobb, G. P., & Anderson, T. A. (2007). microRNAs as oncogenes and tumor suppressors. Developmental Biology, 302(1), 1-12. doi:10.1016/j.ydbio.2006.08.028

Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., … Croce, C. M. (2002). Nonlinear partial differential equations and applications: Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences, 99(24), 15524-15529. doi:10.1073/pnas.242606799

Landi, M. T., Zhao, Y., Rotunno, M., Koshiol, J., Liu, H., Bergen, A. W., … Wang, E. (2010). MicroRNA Expression Differentiates Histology and Predicts Survival of Lung Cancer. Clinical Cancer Research, 16(2), 430-441. doi:10.1158/1078-0432.ccr-09-1736

Takamizawa, J., Konishi, H., Yanagisawa, K., Tomida, S., Osada, H., Endoh, H., … Takahashi, T. (2004). Reduced Expression of thelet-7MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival. Cancer Research, 64(11), 3753-3756. doi:10.1158/0008-5472.can-04-0637

Garofalo, M., Di Leva, G., Romano, G., Nuovo, G., Suh, S.-S., Ngankeu, A., … Croce, C. M. (2009). miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation. Cancer Cell, 16(6), 498-509. doi:10.1016/j.ccr.2009.10.014

Gallardo, E., Navarro, A., Viñolas, N., Marrades, R. M., Diaz, T., Gel, B., … Monzo, M. (2009). miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer. Carcinogenesis, 30(11), 1903-1909. doi:10.1093/carcin/bgp219

Lu, J., Getz, G., Miska, E. A., Alvarez-Saavedra, E., Lamb, J., Peck, D., … Golub, T. R. (2005). MicroRNA expression profiles classify human cancers. Nature, 435(7043), 834-838. doi:10.1038/nature03702

Xi, Y., Nakajima, G., Gavin, E., Morris, C. G., Kudo, K., Hayashi, K., & Ju, J. (2007). Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples. RNA, 13(10), 1668-1674. doi:10.1261/rna.642907

Shen, J., & Jiang, F. (2012). Applications of microRNAs in the diagnosis and prognosis of lung cancer. Expert Opinion on Medical Diagnostics, 6(3), 197-207. doi:10.1517/17530059.2012.672970

Doleshal, M., Magotra, A. A., Choudhury, B., Cannon, B. D., Labourier, E., & Szafranska, A. E. (2008). Evaluation and Validation of Total RNA Extraction Methods for MicroRNA Expression Analyses in Formalin-Fixed, Paraffin-Embedded Tissues. The Journal of Molecular Diagnostics, 10(3), 203-211. doi:10.2353/jmoldx.2008.070153

Taylor, D. D., & Gercel-Taylor, C. (2008). MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecologic Oncology, 110(1), 13-21. doi:10.1016/j.ygyno.2008.04.033

Ibberson, D., Benes, V., Muckenthaler, M. U., & Castoldi, M. (2009). RNA degradation compromises the reliability of microRNA expression profiling. BMC Biotechnology, 9(1), 102. doi:10.1186/1472-6750-9-102

Yin, J. Q., Zhao, R. C., & Morris, K. V. (2008). Profiling microRNA expression with microarrays. Trends in Biotechnology, 26(2), 70-76. doi:10.1016/j.tibtech.2007.11.007

Beuvink, I., Kolb, F. A., Budach, W., Garnier, A., Lange, J., Natt, F., … Weiler, J. (2007). A novel microarray approach reveals new tissue-specific signatures of known and predicted mammalian microRNAs. Nucleic Acids Research, 35(7), e52. doi:10.1093/nar/gkl1118

Raponi, M., Dossey, L., Jatkoe, T., Wu, X., Chen, G., Fan, H., & Beer, D. G. (2009). MicroRNA Classifiers for Predicting Prognosis of Squamous Cell Lung Cancer. Cancer Research, 69(14), 5776-5783. doi:10.1158/0008-5472.can-09-0587

Benes, V., & Castoldi, M. (2010). Expression profiling of microRNA using real-time quantitative PCR, how to use it and what is available. Methods, 50(4), 244-249. doi:10.1016/j.ymeth.2010.01.026

Dijkstra, J. R., Mekenkamp, L. J. M., Teerenstra, S., De Krijger, I., & Nagtegaal, I. D. (2012). MicroRNA expression in formalin-fixed paraffin embedded tissue using real time quantitative PCR: the strengths and pitfalls. Journal of Cellular and Molecular Medicine, 16(4), 683-690. doi:10.1111/j.1582-4934.2011.01467.x

Chen, C. (2005). Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Research, 33(20), e179-e179. doi:10.1093/nar/gni178

Lao, K., Xu, N. L., Yeung, V., Chen, C., Livak, K. J., & Straus, N. A. (2006). Multiplexing RT-PCR for the detection of multiple miRNA species in small samples. Biochemical and Biophysical Research Communications, 343(1), 85-89. doi:10.1016/j.bbrc.2006.02.106

Mestdagh, P., Feys, T., Bernard, N., Guenther, S., Chen, C., Speleman, F., & Vandesompele, J. (2008). High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA. Nucleic Acids Research, 36(21), e143-e143. doi:10.1093/nar/gkn725

Nolan, T., Hands, R. E., & Bustin, S. A. (2006). Quantification of mRNA using real-time RT-PCR. Nature Protocols, 1(3), 1559-1582. doi:10.1038/nprot.2006.236

Zipper, H. (2004). Investigations on DNA intercalation and surface binding by SYBR Green I, its structure determination and methodological implications. Nucleic Acids Research, 32(12), e103-e103. doi:10.1093/nar/gnh101

Mohammadian, A., Mowla, S. J., Elahi, E., Tavallaei, M., Nourani, M. R., & Liang, Y. (2013). Normalization of miRNA qPCR high-throughput data: a comparison of methods. Biotechnology Letters, 35(6), 843-851. doi:10.1007/s10529-013-1150-5

Xie, Y., Todd, N. W., Liu, Z., Zhan, M., Fang, H., Peng, H., … Jiang, F. (2010). Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer. Lung Cancer, 67(2), 170-176. doi:10.1016/j.lungcan.2009.04.004

Yu, S.-L., Chen, H.-Y., Chang, G.-C., Chen, C.-Y., Chen, H.-W., Singh, S., … Yang, P.-C. (2008). MicroRNA Signature Predicts Survival and Relapse in Lung Cancer. Cancer Cell, 13(1), 48-57. doi:10.1016/j.ccr.2007.12.008

Mascaux, C., Laes, J. F., Anthoine, G., Haller, A., Ninane, V., Burny, A., & Sculier, J. P. (2008). Evolution of microRNA expression during human bronchial squamous carcinogenesis. European Respiratory Journal, 33(2), 352-359. doi:10.1183/09031936.00084108

Silva, J., Garcia, V., Zaballos, A., Provencio, M., Lombardia, L., Almonacid, L., … Bonilla, F. (2010). Vesicle-related microRNAs in plasma of nonsmall cell lung cancer patients and correlation with survival. European Respiratory Journal, 37(3), 617-623. doi:10.1183/09031936.00029610

Berghmans, T., Ameye, L., Willems, L., Paesmans, M., Mascaux, C., Lafitte, J. J., … Sculier, J. P. (2013). Identification of microRNA-based signatures for response and survival for non-small cell lung cancer treated with cisplatin-vinorelbine A ELCWP prospective study. Lung Cancer, 82(2), 340-345. doi:10.1016/j.lungcan.2013.07.020

Hennessey, P. T., Sanford, T., Choudhary, A., Mydlarz, W. W., Brown, D., Adai, A. T., … Califano, J. A. (2012). Serum microRNA Biomarkers for Detection of Non-Small Cell Lung Cancer. PLoS ONE, 7(2), e32307. doi:10.1371/journal.pone.0032307

Skrzypski, M., Czapiewski, P., Goryca, K., Jassem, E., Wyrwicz, L., Pawłowski, R., … Jassem, J. (2014). Prognostic value of microRNA expression in operable non-small cell lung cancer patients. British Journal of Cancer, 110(4), 991-1000. doi:10.1038/bjc.2013.786

Cazzoli, R., Buttitta, F., Di Nicola, M., Malatesta, S., Marchetti, A., Rom, W. N., & Pass, H. I. (2013). microRNAs Derived from Circulating Exosomes as Noninvasive Biomarkers for Screening and Diagnosing Lung Cancer. Journal of Thoracic Oncology, 8(9), 1156-1162. doi:10.1097/jto.0b013e318299ac32

Rosenfeld, N., Aharonov, R., Meiri, E., Rosenwald, S., Spector, Y., Zepeniuk, M., … Barshack, I. (2008). MicroRNAs accurately identify cancer tissue origin. Nature Biotechnology, 26(4), 462-469. doi:10.1038/nbt1392

Boeri, M., Verri, C., Conte, D., Roz, L., Modena, P., Facchinetti, F., … Sozzi, G. (2011). MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer. Proceedings of the National Academy of Sciences, 108(9), 3713-3718. doi:10.1073/pnas.1100048108

Yu, L., Todd, N. W., Xing, L., Xie, Y., Zhang, H., Liu, Z., … Jiang, F. (2010). Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers. International Journal of Cancer, 127(12), 2870-2878. doi:10.1002/ijc.25289

Xing, L., Todd, N. W., Yu, L., Fang, H., & Jiang, F. (2010). Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers. Modern Pathology, 23(8), 1157-1164. doi:10.1038/modpathol.2010.111

Shen, J., Todd, N. W., Zhang, H., Yu, L., Lingxiao, X., Mei, Y., … Jiang, F. (2010). Plasma microRNAs as potential biomarkers for non-small-cell lung cancer. Laboratory Investigation, 91(4), 579-587. doi:10.1038/labinvest.2010.194

Campayo, M., Navarro, A., Viñolas, N., Diaz, T., Tejero, R., Gimferrer, J. M., … Marrades, R. (2012). Low miR-145 and high miR-367 are associated with unfavourable prognosis in resected nonsmall cell lung cancer. European Respiratory Journal, 41(5), 1172-1178. doi:10.1183/09031936.00048712

Zhu, W., Liu, X., He, J., Chen, D., Hunag, Y., & Zhang, Y. K. (2011). Overexpression of members of the microRNA-183 family is a risk factor for lung cancer: A case control study. BMC Cancer, 11(1). doi:10.1186/1471-2407-11-393

Duncavage, E., Goodgame, B., Sezhiyan, A., Govindan, R., & Pfeifer, J. (2010). Use of MicroRNA Expression Levels to Predict Outcomes in Resected Stage I Non-small Cell Lung Cancer. Journal of Thoracic Oncology, 5(11), 1755-1763. doi:10.1097/jto.0b013e3181f3909d

Chen, Q., Si, Q., Xiao, S., Xie, Q., Lin, J., Wang, C., … Wang, L. (2012). Prognostic significance of serum miR-17-5p in lung cancer. Medical Oncology, 30(1). doi:10.1007/s12032-012-0353-2

Zhang, H., Su, Y., Xu, F., Kong, J., Yu, H., & Qian, B. (2013). Circulating MicroRNAs in Relation to EGFR Status and Survival of Lung Adenocarcinoma in Female Non-Smokers. PLoS ONE, 8(11), e81408. doi:10.1371/journal.pone.0081408

Garofalo, M., Romano, G., Di Leva, G., Nuovo, G., Jeon, Y.-J., Ngankeu, A., … Croce, C. M. (2011). EGFR and MET receptor tyrosine kinase–altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers. Nature Medicine, 18(1), 74-82. doi:10.1038/nm.2577

Romano, G., Acunzo, M., Garofalo, M., Di Leva, G., Cascione, L., Zanca, C., … Croce, C. M. (2012). MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation. Proceedings of the National Academy of Sciences, 109(41), 16570-16575. doi:10.1073/pnas.1207917109

Kreil, D. P., Russell, R. R., & Russell, S. (2006). [4] Microarray Oligonucleotide Probes. DNA Microarrays, Part A: Array Platforms and Wet-Bench Protocols, 73-98. doi:10.1016/s0076-6879(06)10004-x

KRICHEVSKY, A. M. (2003). A microRNA array reveals extensive regulation of microRNAs during brain development. RNA, 9(10), 1274-1281. doi:10.1261/rna.5980303

SHINGARA, J. (2005). An optimized isolation and labeling platform for accurate microRNA expression profiling. RNA, 11(9), 1461-1470. doi:10.1261/rna.2610405

Castoldi, M. (2006). A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA). RNA, 12(5), 913-920. doi:10.1261/rna.2332406

Wang, H., Ach, R. A., & Curry, B. (2006). Direct and sensitive miRNA profiling from low-input total RNA. RNA, 13(1), 151-159. doi:10.1261/rna.234507

Davison, T. S., Johnson, C. D., & Andruss, B. F. (2006). [2] Analyzing Micro‐RNA Expression Using Microarrays. DNA Microarrays, Part B: Databases and Statistics, 14-34. doi:10.1016/s0076-6879(06)11002-2

Volinia, S., Calin, G. A., Liu, C.-G., Ambs, S., Cimmino, A., Petrocca, F., … Croce, C. M. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proceedings of the National Academy of Sciences, 103(7), 2257-2261. doi:10.1073/pnas.0510565103

Yanaihara, N., Caplen, N., Bowman, E., Seike, M., Kumamoto, K., Yi, M., … Harris, C. C. (2006). Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell, 9(3), 189-198. doi:10.1016/j.ccr.2006.01.025

Patnaik, S. K., Kannisto, E., Knudsen, S., & Yendamuri, S. (2009). Evaluation of MicroRNA Expression Profiles That May Predict Recurrence of Localized Stage I Non-Small Cell Lung Cancer after Surgical Resection. Cancer Research, 70(1), 36-45. doi:10.1158/0008-5472.can-09-3153

Patnaik, S. K., Yendamuri, S., Kannisto, E., Kucharczuk, J. C., Singhal, S., & Vachani, A. (2012). MicroRNA Expression Profiles of Whole Blood in Lung Adenocarcinoma. PLoS ONE, 7(9), e46045. doi:10.1371/journal.pone.0046045

Roth, C., Stückrath, I., Pantel, K., Izbicki, J. R., Tachezy, M., & Schwarzenbach, H. (2012). Low Levels of Cell-Free Circulating miR-361-3p and miR-625* as Blood-Based Markers for Discriminating Malignant from Benign Lung Tumors. PLoS ONE, 7(6), e38248. doi:10.1371/journal.pone.0038248

Metzker, M. L. (2009). Sequencing technologies — the next generation. Nature Reviews Genetics, 11(1), 31-46. doi:10.1038/nrg2626

Margulies, M., Egholm, M., Altman, W. E., Attiya, S., Bader, J. S., Bemben, L. A., … Chen, Z. (2005). Genome sequencing in microfabricated high-density picolitre reactors. Nature, 437(7057), 376-380. doi:10.1038/nature03959

Pritchard, C. C., Cheng, H. H., & Tewari, M. (2012). MicroRNA profiling: approaches and considerations. Nature Reviews Genetics, 13(5), 358-369. doi:10.1038/nrg3198

Beane, J., Vick, J., Schembri, F., Anderlind, C., Gower, A., Campbell, J., … Spira, A. (2011). Characterizing the Impact of Smoking and Lung Cancer on the Airway Transcriptome Using RNA-Seq. Cancer Prevention Research, 4(6), 803-817. doi:10.1158/1940-6207.capr-11-0212

Kalari, K. R., Rossell, D., Necela, B. M., Asmann, Y. W., Nair, A., Baheti, S., … Thompson, E. A. (2012). Deep Sequence Analysis of Non-Small Cell Lung Cancer: Integrated Analysis of Gene Expression, Alternative Splicing, and Single Nucleotide Variations in Lung Adenocarcinomas with and without Oncogenic KRAS Mutations. Frontiers in Oncology, 2. doi:10.3389/fonc.2012.00012

Ju, Y. S., Lee, W.-C., Shin, J.-Y., Lee, S., Bleazard, T., Won, J.-K., … Seo, J.-S. (2011). A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing. Genome Research, 22(3), 436-445. doi:10.1101/gr.133645.111

Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., … Zhang, C.-Y. (2008). Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Research, 18(10), 997-1006. doi:10.1038/cr.2008.282

Hu, Z., Chen, X., Zhao, Y., Tian, T., Jin, G., Shu, Y., … Shen, H. (2010). Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non–Small-Cell Lung Cancer. Journal of Clinical Oncology, 28(10), 1721-1726. doi:10.1200/jco.2009.24.9342

Keller, A., Backes, C., Leidinger, P., Kefer, N., Boisguerin, V., Barbacioru, C., … Meese, E. (2011). Next-generation sequencing identifies novel microRNAs in peripheral blood of lung cancer patients. Molecular BioSystems, 7(12), 3187. doi:10.1039/c1mb05353a

Meng, W., Ye, Z., Cui, R., Perry, J., Dedousi-Huebner, V., Huebner, A., … Lautenschlaeger, T. (2013). MicroRNA-31 Predicts the Presence of Lymph Node Metastases and Survival in Patients with Lung Adenocarcinoma. Clinical Cancer Research, 19(19), 5423-5433. doi:10.1158/1078-0432.ccr-13-0320

Nuovo, G. J. (2010). In situ detection of microRNAs in paraffin embedded, formalin fixed tissues and the co-localization of their putative targets. Methods, 52(4), 307-315. doi:10.1016/j.ymeth.2010.08.009

Jørgensen, S., Baker, A., Møller, S., & Nielsen, B. S. (2010). Robust one-day in situ hybridization protocol for detection of microRNAs in paraffin samples using LNA probes. Methods, 52(4), 375-381. doi:10.1016/j.ymeth.2010.07.002

Wang, S., Aurora, A. B., Johnson, B. A., Qi, X., McAnally, J., Hill, J. A., … Olson, E. N. (2008). The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis. Developmental Cell, 15(2), 261-271. doi:10.1016/j.devcel.2008.07.002

Voortman, J., Goto, A., Mendiboure, J., Sohn, J. J., Schetter, A. J., Saito, M., … Giaccone, G. (2010). MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non-Small Cell Lung Carcinoma. Cancer Research, 70(21), 8288-8298. doi:10.1158/0008-5472.can-10-1348

Nuovo, G. J. (2008). In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations. Methods, 44(1), 39-46. doi:10.1016/j.ymeth.2007.10.008

Donnem, T., Lonvik, K., Eklo, K., Berg, T., Sorbye, S. W., Al-Shibli, K., … Busund, L.-T. (2011). Independent and tissue-specific prognostic impact of miR-126 in nonsmall cell lung cancer. Cancer, 117(14), 3193-3200. doi:10.1002/cncr.25907

Donnem, T., Eklo, K., Berg, T., Sorbye, S. W., Lonvik, K., Al-Saad, S., … Busund, L.-T. (2011). Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization. Journal of Translational Medicine, 9(1). doi:10.1186/1479-5876-9-6

Donnem, T., Fenton, C. G., Lonvik, K., Berg, T., Eklo, K., Andersen, S., … Busund, L.-T. (2012). MicroRNA Signatures in Tumor Tissue Related to Angiogenesis in Non-Small Cell Lung Cancer. PLoS ONE, 7(1), e29671. doi:10.1371/journal.pone.0029671

Eilertsen, M., Andersen, S., Al-Saad, S., Richardsen, E., Stenvold, H., Hald, S. M., … Bremnes, R. M. (2014). Positive prognostic impact of miR-210 in non-small cell lung cancer. Lung Cancer, 83(2), 272-278. doi:10.1016/j.lungcan.2013.11.005

He, L., & Hannon, G. J. (2004). MicroRNAs: small RNAs with a big role in gene regulation. Nature Reviews Genetics, 5(7), 522-531. doi:10.1038/nrg1379

[-]

recommendations

 

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro completo del ítem