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miRNA detection methods and clinical implications in lung cancer

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miRNA detection methods and clinical implications in lung cancer

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dc.contributor.author Usó, Marta es_ES
dc.contributor.author Jantus Lewintre, Eloisa es_ES
dc.contributor.author Sirera Pérez, Rafael es_ES
dc.contributor.author Bremnes, Roy M. es_ES
dc.contributor.author Camps, Carlos es_ES
dc.date.accessioned 2017-03-22T07:49:13Z
dc.date.available 2017-03-22T07:49:13Z
dc.date.issued 2014
dc.identifier.issn 1479-6694
dc.identifier.uri http://hdl.handle.net/10251/78936
dc.description.abstract [EN] Lung cancer is the leading cause of cancer death worldwide. Therefore, advances in the diagnosis and treatment of the disease are urgently needed. miRNAs are a family of small, noncoding RNAs that regulate gene expression at the transcriptional level. miRNAs have been reported to be deregulated and to play a critical role in different types of cancer, including lung cancer. Thus, miRNA profiling in lung cancer patients has become the core of several investigations. To this end, the development of a multitude of platforms for miRNA profiling analysis has been essential. This article focuses on the different technologies available for assessing miRNAs and the most important results obtained to date in lung cancer. es_ES
dc.description.sponsorship This study was partially supported by a grant from the Ministerio de Ciencia e Inovacion de Espana (TRA09-0132), Beca Roche en Onco-Hematologia 2009 and Red Tematica de Investigacion Cooperativa en Cancer (RD12/0036/0025). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
dc.language Inglés es_ES
dc.publisher Future Medicine es_ES
dc.relation MICINN/TRA 09-0132 es_ES
dc.relation RTICC/RD 12/0036/0025 es_ES
dc.relation.ispartof Future Oncology es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Biomarker es_ES
dc.subject Diagnosis es_ES
dc.subject Lung cancer es_ES
dc.subject miRNA es_ES
dc.subject miRNA profiling es_ES
dc.subject Prognosis es_ES
dc.subject.classification MICROBIOLOGIA es_ES
dc.title miRNA detection methods and clinical implications in lung cancer es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.2217/FON.14.93
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural es_ES
dc.description.bibliographicCitation Usó, M.; Jantus Lewintre, E.; Sirera Pérez, R.; Bremnes, RM.; Camps, C. (2014). miRNA detection methods and clinical implications in lung cancer. Future Oncology. 10(14):2279-2292. doi:10.2217/FON.14.93 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.2217/FON.14.93
dc.description.upvformatpinicio 2279 es_ES
dc.description.upvformatpfin 2292 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 10 es_ES
dc.description.issue 14 es_ES
dc.relation.senia 303990 es_ES
dc.identifier.eissn 1744-8301
dc.identifier.pmid 25471039
dc.contributor.funder Ministerio de Ciencia e Innovación
dc.contributor.funder Red Temática de Investigación Cooperativa en Cáncer
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