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Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli.

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Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli.

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Alvarez-Ponce, D.; Sabater-Munoz, B.; Toft, C.; Ruíz-González, MJ.; Fares Riaño, MA. (2016). Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli. Genome Biology and Evolution. 8(9):2914-2927. doi:10.1093/gbe/evw205

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/81366

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Title: Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli.
Author:
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
Issued date:
Abstract:
[EN] The Neutral Theory of Molecular Evolution is considered the most powerful theory to understand the evolutionary behavior of proteins. One of the main predictions of this theory is that essential proteins should evolve ...[+]
Subjects: Essentiality , Rates of evolution , dN/dS , Experimental evolution , Neutral theory
Copyrigths: Reconocimiento - No comercial (by-nc)
Source:
Genome Biology and Evolution. (issn: 1759-6653 )
DOI: 10.1093/gbe/evw205
Publisher:
Oxford University Press (OUP)
Publisher version: http://dx.doi.org/10.1093/gbe/evw205
Thanks:
We are grateful to Kais Fares, Maria Prats-Escriche and Victor Berlanga-Laparra for technical assistance with the evolution experiments. We are also grateful to the Editor and two anonymous referees for helpful comments. ...[+]
Type: Artículo

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