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Nitric oxide triggers a transient metabolic reprogramming in Arabidopsis

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Nitric oxide triggers a transient metabolic reprogramming in Arabidopsis

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dc.contributor.author Leon Ramos, Jose es_ES
dc.contributor.author Costa-Broseta, Álvaro es_ES
dc.contributor.author Castillo López del Toro, Mª Cruz es_ES
dc.date.accessioned 2017-06-06T09:27:07Z
dc.date.available 2017-06-06T09:27:07Z
dc.date.issued 2016-11-25
dc.identifier.issn 2045-2322
dc.identifier.uri http://hdl.handle.net/10251/82411
dc.description.abstract [EN] Nitric oxide (NO) regulates plant growth and development as well as responses to stress that enhanced its endogenous production. Arabidopsis plants exposed to a pulse of exogenous NO gas were used for untargeted global metabolomic analyses thus allowing the identification of metabolic processes affected by NO. At early time points after treatment, NO scavenged superoxide anion and induced the nitration and the S-nitrosylation of proteins. These events preceded an extensive though transient metabolic reprogramming at 6 h after NO treatment, which included enhanced levels of polyamines, lipid catabolism and accumulation of phospholipids, chlorophyll breakdown, protein and nucleic acid turnover and increased content of sugars. Accordingly, lipid-related structures such as root cell membranes and leaf cuticle altered their permeability upon NO treatment. Besides, NO-treated plants displayed degradation of starch granules, which is consistent with the increased sugar content observed in the metabolomic survey. The metabolic profile was restored to baseline levels at 24 h post-treatment, thus pointing up the plasticity of plant metabolism in response to nitroxidative stress conditions. es_ES
dc.description.sponsorship This work was supported by grants BIO2011-27526 and BIO2014-56067-P from the Spanish Ministry of Economy and Competitiveness and FEDER funds. We thank support and comments from Danny Alexander (Metabolon Inc., USA) on metabolomic analyses. en_EN
dc.language Inglés es_ES
dc.publisher Nature Publishing Group es_ES
dc.relation.ispartof Scientific Reports es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Programmed cell-death es_ES
dc.subject Tyrosine nitration es_ES
dc.subject Abiotic stress es_ES
dc.subject Plant-cells es_ES
dc.subject Posttranslational modification es_ES
dc.subject Clorophyll breakdown es_ES
dc.subject Signaling pathways es_ES
dc.subject Redox balance es_ES
dc.subject Degradation es_ES
dc.subject Responses es_ES
dc.title Nitric oxide triggers a transient metabolic reprogramming in Arabidopsis es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1038/srep37945
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//BIO2011-27526/ES/EL OXIDO NITRICO COMO MODULADOR DE LA SEÑALIZACION MEDIADA POR ABA Y GIBERELINAS EN ARABIDOPSIS/ / es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//BIO2014-56067-P/ES/CONTROL DE LA PRODUCCION, PERCEPCION Y SEÑALIZACION DE NO POR MODIFICACIONES POSTRADUCCIONALES Y PROTEOLISIS DIRIGIDA POR LA SECUENCIA AMINOTERMINAL/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes es_ES
dc.description.bibliographicCitation Leon Ramos, J.; Costa-Broseta, Á.; Castillo López Del Toro, MC. (2016). Nitric oxide triggers a transient metabolic reprogramming in Arabidopsis. Scientific Reports. 6:1-14. doi:10.1038/srep37945 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://doi.org/10.1038/srep37945 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 14 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 6 es_ES
dc.relation.senia 321591 es_ES
dc.identifier.pmid 27885260 en_EN
dc.identifier.pmcid PMC5122866
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