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Native immunity and oxidative traits of growing rabbits

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Native immunity and oxidative traits of growing rabbits

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dc.contributor.author Moscati, L.
dc.contributor.author Dal Bosco, A.
dc.contributor.author Battistacci, L.
dc.contributor.author Cardinali, R.
dc.contributor.author Mugnai, C.
dc.contributor.author Castellini, C.
dc.date.accessioned 2011-02-08T14:02:08Z
dc.date.available 2011-02-08T14:02:08Z
dc.date.issued 2008
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/9512
dc.description.abstract [EN] The evaluation of animal welfare through innate immunity (Serum Bactericidal Activity - SBA, Hemolytic Complement Assay - HCA, lysozyme) and the antioxidant status of the body (Reactive Oxygen Substances - ROS and Antioxidant Power of plasma, AP) offers a reliable prognostic and diagnostic tool. The aim of the present study was to investigate trends and correlations between some traits of innate immunity and the oxidative status of fattening rabbits at different ages. Blood samples from 120 New Zealand White fattening rabbits at 45, 55, 65, and 75 d of age were collected and analyzed. The results showed that SBA did not have a normal distribution because of numerous 0 values. Data distribution was normal when only SBA > 0 values were considered. Lysozyme (mean value 27.19 microg/mL) and HCA (mean value 50.84 CH50% ) had stable trends at different ages and showed a tendency that was comparable to that obtained in other animal species. On the contrary, SBA (mean value 42.15%) showed an unexpected positive correlation with lysozyme (P<0.001) and a negative correlation with HCA (P<0.001). Oxygen free-radicals are involved in the pathogenesis of several diseases and oxidative stress alters immune competence. In this experiment, ROS and AP showed mean values of 0.60 mmol H2 O2 and 421.67 micromol HClO, respectively. In this context positive correlation coefficients between oxidative status traits and immune traits (P<0.001) were found, although at a very low level; and surprisingly, only ROS and SBA did not show any significant correlation. In this study it emerged that, even in the absence of evident pathologies, the immune and oxidative traits of fattening rabbits could be affected by environmental stress (weaning, cage, neighbors) es_ES
dc.description.sponsorship Funded by Ricerca Corrente 2006 Istituto Zooprofilattico Sperimentale dell’Umbria e Marche
dc.language Inglés es_ES
dc.publisher World Rabbit Science. ICTA. UPV es_ES
dc.relation.ispartof World Rabbit Science
dc.rights Reconocimiento - No comercial (by-nc) es_ES
dc.subject Rabbit es_ES
dc.subject Welfare es_ES
dc.subject Immunity parameters es_ES
dc.subject Oxidative status es_ES
dc.title Native immunity and oxidative traits of growing rabbits es_ES
dc.type Artículo es_ES
dc.date.updated 2011-02-08T13:10:07Z
dc.identifier.doi 10.4995/wrs.2008.616
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Moscati, L.; Dal Bosco, A.; Battistacci, L.; Cardinali, R.; Mugnai, C.; Castellini, C. (2008). Native immunity and oxidative traits of growing rabbits. World Rabbit Science. 16(4). doi:10.4995/wrs.2008.616 es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2008.616
dc.description.volume 16
dc.description.issue 4
dc.identifier.eissn 1989-8886 es_ES


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