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Computer modeling of an impedance-controlled pulsing protocol for RF tumor ablation with a cooled electrode

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Computer modeling of an impedance-controlled pulsing protocol for RF tumor ablation with a cooled electrode

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dc.contributor.author Trujillo Guillen, Macarena es_ES
dc.contributor.author Bon Corbín, José es_ES
dc.contributor.author Rivera Ortun, María José es_ES
dc.contributor.author Burdio, Fernando es_ES
dc.contributor.author Berjano, Enrique es_ES
dc.date.accessioned 2018-03-09T05:29:28Z
dc.date.available 2018-03-09T05:29:28Z
dc.date.issued 2016 es_ES
dc.identifier.issn 0265-6736 es_ES
dc.identifier.uri http://hdl.handle.net/10251/99060
dc.description.abstract [EN] Purpose: To develop computer models to mimic the impedance-controlled pulsing protocol implemented in radiofrequency (RF) generators used for clinical practice of radiofrequency ablation (RFA), and to assess the appropriateness of the models by comparing the computer results with those obtained in previous experimental studies.Methods: A 12-min RFA was modelled using a cooled electrode (17G, 3cm tip) inserted in hepatic tissue. The short (transverse) diameter of the coagulation zone was assessed under in vivo (with blood perfusion (BP) and considering clamping) and ex vivo (at 21 degrees C) conditions. The computer results obtained by programming voltage pulses were compared with current pulses.Results: The differences between voltage and current pulses were noticeable: using current instead of voltage allows larger coagulation zones to be created, due to the higher energy applied by current pulses. If voltage pulses are employed the model can accurately predict the number of roll-offs, although the waveform of the applied power is clearly not realistic. If current voltages are employed, the applied power waveform matches well with those reported experimentally, but there are significantly fewer roll-offs. Our computer results were overall into the ranges of experimental ones.Conclusions: The proposed models reproduce reasonably well the electrical-thermal performance and coagulation zone size obtained during an impedance-controlled pulsing protocol. es_ES
dc.description.sponsorship This work was supported by the Spanish Plan Estatal de Investigacion, Desarrollo e Innovacion Orientada a los Retos de la Sociedad under grant number TEC2014-52383-C3-R (TEC2014-52383-C3-1-R). The authors alone are responsible for the content and writing of the paper. en_EN
dc.language Inglés es_ES
dc.publisher Taylor & Francis es_ES
dc.relation info:eu-repo/grantAgreement/MINECO//TEC2014-52383-C3-1-R/ES/TECNOLOGIAS BASADAS EN ENERGIA DE RADIOFRECUENCIA Y MICROONDAS PARA CIRUGIA DE MINIMA INVASION/ es_ES
dc.relation.ispartof International Journal of Hyperthermia es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Cooled electrode es_ES
dc.subject Finite element method es_ES
dc.subject Impedance control es_ES
dc.subject Pulsing protocol es_ES
dc.subject Radiofrequency ablation es_ES
dc.subject Thermal ablation es_ES
dc.subject Tumour ablation es_ES
dc.subject.classification MATEMATICA APLICADA es_ES
dc.subject.classification TECNOLOGIA DE ALIMENTOS es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Computer modeling of an impedance-controlled pulsing protocol for RF tumor ablation with a cooled electrode es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1080/02656736.2016.1190868 es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Tecnología de Alimentos - Departament de Tecnologia d'Aliments es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Matemática Aplicada - Departament de Matemàtica Aplicada es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.description.bibliographicCitation Trujillo Guillen, M.; Bon Corbín, J.; Rivera Ortun, MJ.; Burdio, F.; Berjano, E. (2016). Computer modeling of an impedance-controlled pulsing protocol for RF tumor ablation with a cooled electrode. International Journal of Hyperthermia. 32(8):931-939. doi:10.1080/02656736.2016.1190868 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1080/02656736.2016.1190868 es_ES
dc.description.upvformatpinicio 931 es_ES
dc.description.upvformatpfin 939 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 32 es_ES
dc.description.issue 8 es_ES
dc.relation.pasarela S\318816 es_ES
dc.contributor.funder Ministerio de Economía, Industria y Competitividad es_ES


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