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Browsing by Author "Cortes, Diego"

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Browsing by Author "Cortes, Diego"

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    2,3,9- and 2,3,11-Trisubstituted tetrahydroprotoberberines as D2 dopaminergic ligands 
    Párraga, Javier; Cabedo Escrig, Nuria; Andujar, Sebastián; Piqueras, Laura; Moreno, Laura; Galán, Abraham; Angelina, Emilio; Enriz, Ricardo D.; Ivorra, María Dolores; Sanz, María Jesús; Cortes, Diego (Elsevier, 2013-10)
    Dopamine-mediated neurotransmission plays an important role in relevant psychiatric and neurological disorders. Nowadays, there is an enormous interest in the development of new dopamine receptors (DR) acting drugs as ...
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    Structure-activity relationship of dopaminergic halogenated 1-benzyl-tetrahydroisoquinoline derivatives 
    El Aouad, Noureddine; Berenguer, Inmaculada; Romero, Vanessa; Marin, Paloma; Serrano, Angel; Andujar, Sebastian; Suvire, Fernando; Bermejo, Almudena; Ivorra, M. Dolores; Enriz, Ricardo D.; Cabedo Escrig, Nuria; Cortes, Diego (Elsevier, 2009-11)
    Two series of halogenated 1-benzyl-7-chloro-6-hydroxy-tetrahydroisoquinolines were prepared to explore the influence of each series on the affinity for dopamine receptors. All the compounds displayed a high affinity for ...
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    Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones 
    Moreno, Laura; Parraga, Javier; Galan, Abraham; Cabedo Escrig, Nuria; Primo Millo, Jaime; Cortes, Diego (Elsevier, 2012-11-12)
    The attractive structure of the pyrroloisoquinoline moiety, together with its potential antimicrobial activity, encouraged us to prepare six 8-substituted and seven 8,9-disubstituted-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a] ...
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    Tetrahydroisoquinolines functionalized with carbamates as selective ligands of D2 dopamine receptor 
    Parravicini, Oscar; Bogado, M. Lucrecia; Rojas, Sebastián; Angelina, Emilio L.; Andujar, Sebastián A.; Gutierrez, Lucas J.; Cabedo Escrig, Nuria; López-Gresa, María Pilar; Sanz, M. Jesús; Cortes, Diego; Enriz, Ricardo D. (Springer-Verlag, 2017-09)
    [EN] A series of tetrahydroisoquinolines functionalized with carbamates is reported here as highly selective ligands on the dopamine D2 receptor. These compounds were selected by means of a molecular modeling study. The ...