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Browsing by Author "Giménez Romero, David"

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Browsing by Author "Giménez Romero, David"

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    Dual-Polarization Interferometry: A Novel Technique To Light up the Nanomolecular World 
    Escorihuela Fuentes, Jorge; González Martínez, Miguel Ángel; López-Paz, José Luis; Puchades, Rosa; Maquieira Catala, Ángel; Giménez Romero, David (American Chemical Society, 2015-01-14)
    [EN] The challenging lecture given in 1959 by physicist and Nobel Prize awarded R. P. Feynman: “There's plenty of room at the bottom” is considered to be the starting point for nanotechnology. With this peculiar title, ...
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    Elucidation of Carbohydrate Molecular Interaction Mechanism of Recombinant and Native ArtinM 
    Giménez Romero, David; Roberto Bueno, Paulo; Pesquero, Naira C.; Monzó, Isidro S.; Puchades, Rosa; Maquieira Catala, Ángel (American Chemical Society, 2013-07-18)
    [EN] The quartz crystal microbalance (QCM) technique has been applied for monitoring the biorecognition of ArtinM lectins at low horseradish peroxidase glycoprotein (HRP) concentrations, using a simple kinetic model based ...
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    Enzyme Inhibition Microassays on Blu-Ray Disks for Drug Discovery 
    Sancho-Fornes, Gabriel; Peris Chanzá, Ernesto José; Giménez-Romero, David; Morais, Sergi; Maquieira Catala, Angel (American Chemical Society, 2019)
    [EN] An enzyme inhibition-based assay for drug discovery developed by microarraing on Blu-ray disks is presented. As a proof-of-concept, the system screens a selected molecule library of potential chemical inhibitors against ...
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    INSEL: An in silico method for optimizing and exploring biorecognition assays 
    Avella-Oliver, Miquel; Giménez Romero, David; Morais, Sergi; González Martínez, Miguel Ángel; Bueno, Paulo Roberto; Puchades, Rosa; Maquieira Catala, Ángel (Royal Society of Chemistry, 2013)
    [EN] A practical in silico method for optimizing and exploring biointeraction-based events is developed.
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    Label-free piezoelectric biosensor for prognosis and diagnosis of Systemic Lupus Erythematosus 
    do Nascimento, Noelle M.; Juste-Dolz, Augusto; Grau-García, Elena; Roman-Ivorra, Jose A.; Puchades, Rosa; Maquieira Catala, Angel; Morais, Sergi; Giménez-Romero, David (Elsevier, 2017)
    [EN] An autoantigen piezoelectric sensor to quantify specific circulating autoantibodies in human serum is developed. The sensor consisted on a quartz crystal microbalance with dissipation monitoring (QCM-D) where TRIM21 ...
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    Mapping molecular binding by means of conformational dynamics measurements 
    Do Nascimento, Noelle M.; Juste-Dolz, Augusto Miguel; Bueno, Paulo Roberto; Monzó, Isidro S.; Tejero, R.; López-Paz, José Luis; Maquieira Catala, Angel; Morais, Sergi; Giménez-Romero, David (The Royal Society of Chemistry, 2018-01)
    [EN] Protein-protein interactions are key in virtually all biological processes. The study of these interactions and the interfaces that mediate them play a key role in the understanding of biological function. In particular, ...
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    New structural insights into the role of TROVE2 complexes in the on-set and pathogenesis of systemic lupus eythematosus determined by a combiantion of QCM-D and DPI 
    Juste-Dolz, Augusto Miguel; Do Nascimento, Noelle Mariane; Monzó, Isidro S.; Grau-García, Elena; Roman-Ivorra, J. A.; López-Paz, José Luis; Escorihuela Fuentes, Jorge; Puchades, Rosa; Morais, Sergi; Giménez-Romero, David; Maquieira Catala, Angel (Springer-Verlag, 2019-07)
    [EN] The mechanism of self-recognition of the autoantigen TROVE2, a common biomarker in autoimmune diseases, has been studied with a quartz crystal microbalance with dissipation monitoring (QCM-D) and dual polarization ...
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    The Ro/SSA Complex in Systemic Lupus Erythematosus Patients 
    Do Nascimento, Noelle Mariane (Universitat Politècnica de València, 2017-05-04)
    In this work the involved mechanisms between Ro/SSA complex, composed also by the tripartite motif 21 (TRIM21alpha) and trove domain 2 (TROVE2) proteins, with respect to systemic lupus erythematosus (SLE) autoantibodies ...