Dopamine-mediated neurotransmission plays an important role in relevant psychiatric and neurological disorders. Nowadays, there is an enormous interest in the development of new dopamine receptors (DR) acting drugs as ...
Parravicini, Oscar; Bogado, M. Lucrecia; Rojas, Sebastián; Angelina, Emilio L.; Andujar, Sebastián A.; Gutierrez, Lucas J.; Cabedo Escrig, Nuria; López-Gresa, María Pilar; Sanz, M. Jesús; Cortes, Diego; Enriz, Ricardo D.(Springer-Verlag, 2017-09)
[EN] A series of tetrahydroisoquinolines functionalized with carbamates is reported here as highly selective ligands on the dopamine D2 receptor. These compounds were selected by means of a molecular modeling study. The ...