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Browsing by Author "Martínez Climent, Batiste Andreu"

Now showing items 1-20 of 43

Algoritmo de reconocimiento de patrones basado en codificación fisiológica en cerebro de primates

Castel Baixauli, Alejandro (Universitat Politècnica de València, 2017-12-13)

El cerebro humano y animal es capaz de reconocer una gran cantidad de patrones, como por ejemplo caras, utilizando un limitado número de neuronas y algoritmos de procesamiento [Chang et al 2017]. Sin embargo, los algoritmos ...
Analysis of the response of human iPSC-derived cardiomyocyte tissue to I CaL block. A combined in vitro and in silico approach

Dasí, Albert; Hernández-Romero, Ismael; Gómez, Juan F.; Climent, Andreu M.; Ferrero De Loma-Osorio, José María; Trenor Gomis, Beatriz Ana (Elsevier, 2021-10)

[EN] The high incidence of cardiac arrythmias underlines the need for the assessment of pharmacological therapies. In this field of drug efficacy, as in the field of drug safety highlighted by the Comprehensive in Vitro ...
Análisis Comparativo de la Familia xRIO de National Instruments para el Registro Multicanal de Potenciales Cardíacos

Liberos Mascarell, Alejandro (Universitat Politècnica de València, 2011-11-29)

El objetivo de este trabajo es describir y testear una novedosa arquitectura para el registro multicanal de potenciales cardíacos basada en LabVIEW: la Arquitectura Reconfigurable para el Mapeo Eléctrico (RAEM). La ...
Automatic quality electrogram assessment improves phase-based reentrant activity identification in atrial fibrillation

Costoya-Sánchez, Alejandro; Climent, Andreu M.; Hernández-Romero, Ismael; Liberos Mascarell, Alejandro; Fernández-Avilés, Francisco; Narayan, Sanjiv M.; Atienza, Felipe; Guillem Sánchez, María Salud; RODRIGO BORT, MIGUEL (Elsevier, 2020-02)

[EN] Identification of reentrant activity driving atrial fibrillation (AF) is increasingly important to ablative therapies. The goal of this work is to study how the automatically-classified quality of the electrograms ...
Automatic Quality Electrogram Assessment Improves Reentrant Activity Identification in Atrial Fibrillation

Costoya-Sánchez, Alejandro; Climent, Andreu M.; Hernández-Romero, Ismael; Liberos, Alejandro; Fernández-Avilés, Francisco; Narayan, Sanjiv M.; Atienza, Felipe; Guillem Sánchez, María Salud; Rodrigo, Miguel (IEEE, 2019-09-11)

[EN] Location of reentrant electrical activity responsible for driving atrial fibrillation (AF) is key to ablative therapies. The aim of this work is to study the effect of the quality of the electrograms (EGMs) used for ...
Blocking L-Type Calcium Current Reduces Vulnerability to Re-Entry in Human iPSC-Derived Cardiomyocytes Tissue

Dasi, Albert; Climent, Andreu M.; Martínez, Laura; Gómez, Juan F.; Ferrero De Loma-Osorio, José María; Trenor Gomis, Beatriz Ana (IEEE, 2019-09-11)

[EN] Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have proven to be crucial in pharmacological assessment. Nevertheless, their response to drugs when coupled forming a tissue is not fully understood. ...
Characterization and Modeling of Atrioventricular Conduction during Atrial Fibrillation

Martínez Climent, Batiste Andreu (Universitat Politècnica de València, 2011-06-03)

La fibrilación auricular (FA) es una de las arritmias cardiacas más comunes, la cual afecta alrededor del 10% de la población de más de 70 años. En FA, los impulsos eléctricos auriculares generados por el nodo sinusal son ...
Classification of atrial ectopic origins into spatial segments based on the 12-lead ECG

Álvarez Guirado, Pedro (Universitat Politècnica de València, 2018-10-04)

The aim of this thesis is to study, whether the standard 12-lead ECG can be used to localize the origin of atrial ectopic beats. A neural network shall be used to classify ECG signals into predefined spatial segments of ...
Clinical Characteristics and Electrophysiological Mechanisms Underlying Brugada ECG in Patients With Severe Hyperkalemia

Rivera-Juárez, Allan; Hernández-Romero, Ismael; Puertas, Carolina; Zhang-Wang, Serena; Sánchez-Álamo, Beatriz; Martins, Raphael; Figuera, Carlos; Guillem Sánchez, María Salud; Martínez Climent, Batiste Andreu; Fernández-Avilés, Francisco; Tejedor, Alberto; Jalife, José; Atienza, Felipe (John Wiley & Sons, 2019-02-05)

[EN] Background-Several metabolic conditions can cause the Brugada ECG pattern, also called Brugada phenotype (BrPh). We aimed to define the clinical characteristics and outcome of BrPh patients and elucidate the mechanisms ...
Desarrollo de un algoritmo para la evaluación de la frecuencia dominante mediante registros invasivos y no invasivos durante fibrilación auricular

Torre Costa, Javier de la (Universitat Politècnica de València, 2017-09-01)

[ES] La fibrilación auricular (FA) es la arritmia cardíaca más frecuente, afecta a un 2% de la población general y conlleva una importante morbilidad asociada. A pesar de ello, los mecanismos electrofi ...
Desarrollo de un estimulador eléctrico programable para el entrenamiento de corazones bioartificiales

MONTAÑANA GRAU, ROBERTO (Universitat Politècnica de València, 2015-01-30)

Diversos estudios médicos han concluido que es posible regenerar tejido cardíaco a partir de células madre. A pesar de ello, la tasa de supervivencia de dichos corazones resulta inferior al 10%. Un preacondicionamiento ...
Desarrollo de un estimulador eléctromecánico programable para el entrenamiento electromecánico de cultivos monocapas de células miocárdicas

Pla Terrada, Oscar Alberto (Universitat Politècnica de València, 2017-12-12)

Several medical studies have concluded that it is possible to regenerate cardiac tissue from stem cells. However, the survival rate of the stem cells implanted in hearts is less than 10%. A previous electromechanic ...
Desarrollo de un prototipo de biorreactor con sistema de intercambio de medios de cultivo

León Ortuño, Ana Leonor (Universitat Politècnica de València, 2016-07-12)

[ES] En el presente Trabajo Final de Grado se ha desarrollado un prototipo de biorreactor basado en un sistema automático de intercambio del medio de cultivo presente en una siembra de células, que permite mantener unas ...
Desarrollo de un prototipo para la localización espacial tridimensional de catéteres por medidas de impedancia eléctrica

Ruz Castro, Javier (Universitat Politècnica de València, 2017-12-02)

Atrial fibrillation is known as the most common arrhythmia in clinical practice, affecting more than 1% of the adult population. This pathology reduces the quality of life of its patients, and drastically increases ...
Desarrollo de un sistema de preservación y perfusión de órganos aislados

Olivares Velencoso, Vanesa (Universitat Politècnica de València, 2017-12-12)

Nowadays, organ transplants have brought a revolution in the field of Medicine. They are a daily routine in hospitals, being the liver transplants one of most common. Because of a very short supply, organs from elderly ...
Desarrollo y validación de un sistema de caracterización electrofisiológica cardiaca mediante mapeo óptico en un modelo de corazón aislado porcino

Albert Martínez, Ramón (Universitat Politècnica de València, 2016-03-11)

[EN] In order to know more about the causes, reasons of origin and perpetuation of AF, a system of control, monitoring and recording for experimenting with isolated pig heart has been designed and implemented. The solution ...
Detección de patrones de activación eléctrica cardiaca mediante medidas de causalidad

Tomás González, Esther (Universitat Politècnica de València, 2017-12-12)

The atrial fibrillation is one of the most common cardiac arrhythmia. It consists on an irregular propagations of the electric activity in the cardiac tissue. This anomaly causes inefficiency in the physiological activity ...
Effects of Geometry in Atrial Fibrillation Markers Obtained With Electrocardiographic Imaging

Molero-Alabau, Rubén; Climent, Andreu M.; Hernández-Romero, Ismael; Liberos, Alejandro; Fernández-Avilés, Francisco; Atienza, Felipe; Guillem Sánchez, María Salud; Rodrigo, Miguel (IEEE, 2019-09-11)

[EN] Electrocardiographic imaging (ECGI) can characterise cardiac pathologies such as atrial fibrillation (AF) through specific markers based on frequency or phase analysis. In this study, the effect of the geometry of ...
Electrocardiographic Imaging for Atrial Fibrillation: A Perspective From Computer Models and Animal Experiments to Clinical Value

Salinet, Joao; Molero-Alabau, Rubén; Schlindwein, Fernando S.; Karel, Joël; Rodrigo, Miguel; Rojo-Álvarez, José Luis; Berenfeld, Omer; Climent, Andreu M.; Zenger, Brian; Vanheusden, Frederique; Siles Paredes, Jimena Gabriela; MacLeod, Rob; Atienza, Felipe; Guillem Sánchez, María Salud; Cluitmans, Matthijs; Bonizzi, Pietro (Frontiers Media SA, 2021-04-30)

[EN] Electrocardiographic imaging (ECGI) is a technique to reconstruct non-invasively the electrical activity on the heart surface from body-surface potential recordings and geometric information of the torso and the heart. ...
Electrocardiographic imaging including intracardiac information to achieve accurate global mapping during atrial fibrillation

Cámara-Vázquez, Miguel Ángel; Hernández-Romero, Ismael; Rodrigo, Miguel; Alonso-Atienza, Felipe; Figuera, Carlos; Morgado-Reyes, Eduardo; Atienza, Felipe; Guillem Sánchez, María Salud; Climent, Andreu M.; Barquero-Pérez, Óscar (Elsevier, 2021-02)

[EN] Atrial fibrillation (AF) is characterized by complex and irregular propagation patterns. Noninvasive electrocardiographic imaging (ECGI) has been tested during AF conditions with promising results. However, current ...