Background: This study sought to determine pro-B-type natriuretic peptide (proBNP), BNP, N-terminal proBNP (NT-proBNP) and GATA-4 in the same cardiac tissue, the correlation among them, and the influence of ischemic etiology ...
Mora Fenoll, Mª Teresa(Universitat Politècnica de València, 2020-10-26)
[EN] Heart failure, a cardiomyopathy that produces mechanical dysfunction and sudden cardiac death following fatal arrhythmias, is one of the main causes of mortality worldwide that also causes elevated morbidity rates. ...
[EN] We investigate for the first time the influence of heart failure (HF) on nucleolar organization and proteins in patients with ischemic (ICM) or dilated cardiomyopathy (DCM). A total of 71 human hearts from ICM (n= 38) ...
Mora-Fenoll, María Teresa; Zaza, Antonio; Trenor Gomis, Beatriz Ana(Elsevier, 2023-01-21)
[EN] Background and objective: Structural and electrical remodeling in heart failure predisposes the heart to
ventricular arrhythmias. Computer modeling approaches, used to complement experimental results, can
provide a ...
Carpio-Garay, Edison Fernando; Gómez García, Juan Francisco; Sebastian, Rafael; López-Pérez, Alejandro Daniel; Castellanos, Eduardo; Almendral, Jesús; Ferrero De Loma-Osorio, José María; Trenor Gomis, Beatriz Ana(Frontiers Media SA, 2019-02-11)
[EN] Patients suffering from heart failure and left bundle branch block show electrical ventricular dyssynchrony causing an abnormal blood pumping. Cardiac resynchronization therapy (CRT) is recommended for these patients. ...
Aerts, Hannelore; Kalra, Dipak; Sáez Silvestre, Carlos; Ramírez-Anguita, Juan Manuel; Mayer, Miguel-Angel; Garcia-Gomez, Juan M; Durá-Hernández, Marta; Thienpont, Geert; Coorevits, Pascal(JMIR Publications Inc., 2021-08)
[EN] Background: There is increasing recognition that health care providers need to focus attention, and be judged against, the impact they have on the health outcomes experienced by patients. The measurement of health ...
Holzem, Katherine M.; Gómez García, Juan Francisco; Glukhov, Alexey V.; Madden, Eli J.; Koppel, Aaron C.; Ewald, Gregory A.; Trénor Gomis, Beatriz Ana; Efimov, Igor R.(Elsevier, 2016-07)
Heart failure (HF) claims 250,000 lives per year in the US, and nearly half of these deaths are sudden and presumably
due to ventricular tachyarrhythmias. QT interval and action potential (AP) prolongation are hallmark ...
[EN] BACKGROUND: The mechanisms explaining the clinical benefits of ferric carboximaltose (FCM) in patients with heart failure, reduced or intermediate left ventricular ejection fraction, and iron deficiency remain not ...
Trénor Gomis, Beatriz Ana; Cardona Urrego, Karen Eliana; Gómez García, Juan Francisco; Rajamani, Sridharan; Ferrero De Loma-Osorio, José María; Belardinelli, Luiz; Saiz Rodríguez, Francisco Javier(Public Library of Science, 2012)
Heart failure constitutes a major public health problem worldwide. The electrophysiological remodeling of failing hearts sets the stage for malignant arrhythmias, in which the role of the late Na + current (I NaL) is ...
Mora-Fenoll, María Teresa; Gong, Jingqi Q. X.; Sobie, Eric A.; Trenor Gomis, Beatriz Ana(Elsevier, 2021-04)
[EN] ß-adrenergic receptor antagonists (ß-blockers) are extensively used to improve cardiac performance in heart failure (HF), but the electrical improvements with these clinical treatments are not fully understood. The ...
Imedio Rivero, Sara(Universitat Politècnica de València, 2023-07-05)
[ES] La insuficiencia cardiaca (IC) es una de las principales causas de morbimortalidad en la actualidad pese a los continuos avances en el tratamiento. La bioimpedancia se presenta como una técnica prometedora para el ...