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Listar por autor "Elena Fito, Santiago Fco"

Mostrando ítems 21-40 de 106

Differences in accumulation and virulence determine the outcome of competition during Tobacco etch virus coinfection

Lafforgue, Guillaume; Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco (Public Library of Science, 2011-03-15)

[EN] Understanding the evolution of virulence for RNA viruses is essential for developing appropriate control strategies. Although it has been usually assumed that virulence is a consequence of within-host replication of ...
Diminishing returns of inoculum size on the rate of a plant RNA virus evolution

Navarro, Rebeca; Ambros Palaguerri, Silvia; Martinez, Fernando; Elena Fito, Santiago Fco. (IOP Publishing - Europhysics Letters, 2017)

[EN] Understanding how genetic drift, mutation and selection interplay in determining the evolutionary fate of populations is one of the central themes of Evolutionary Biology. Theory predicts that by increasing the number ...
Dynamics of a plant RNA virus intracellular accumulation: stamping machine versus geometric replication

Martinez, Fernando; Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco; Daros Arnau, Jose Antonio (Genetics Society of America, 2011-07)

[EN] The tremendous evolutionary potential of RNA viruses allows them to thrive despite host defense mechanisms and endows them with properties such as emergence, host switching, and virulence. The frequency of mutant ...
Dynamics of alternative modes of RNA replication for positive-sense RNA viruses

Sardanyes Cayuela, Jose; Martinez, Fernando; Daros Arnau, Jose Antonio; Elena Fito, Santiago Fco (Royal Society, The, 2012-04-07)

[EN] We propose and study nonlinear mathematical models describing the intracellular time dynamics of viral RNA accumulation for positive-sense single-stranded RNA viruses. Our models consider different replication modes ...
Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV

Wu, Beilei; Blanchard-Letort, Alexandra; Liu, Yan; Zhou, Guanghe; Wang, Xifeng; Elena Fito, Santiago Fco (Public Library of Science, 2011)

[EN] Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both ...
Dynamics of potyvirus systemic infection establishment: independent yet cumulative action of primary infection sites

Lafforgue, Guillaume; Tromas, Nicolas; Elena Fito, Santiago Fco; Zwart, Mark Peter (American Society for Microbiology, 2012)

[EN] In the clinic, farm, or field, for many viruses there is a high prevalence of mixed-genotype infections, indicating that multiple virions have initiated infection and that there can be multiple sites of primary infection ...
Effect of host species on the distribution of mutational fitness effects for an RNA virus

Lalic ., Jasna; CUEVAS, J.M; Elena Fito, Santiago Fco (Public Library of Science, 2011-10-17)

Knowledge about the distribution of mutational fitness effects (DMFE) is essential for many evolutionary models. In recent years, the properties of the DMFE have been carefully described for some microorganisms. In most ...
Effect of host species on the topography of fitness landscape for a plant RNA virus

Cervera-Benet, Héctor; Lalic, Jasna; Elena Fito, Santiago Fco (American Society for Microbiology, 2016-11)

[EN] Adaptive fitness landscapes are a fundamental concept in evolutionary biology that relate the genotype of individuals with their fitness. At the end, the evolutionary fate of evolving populations depends on the ...
Effect of Potyvirus effective population size in inoculated leaves on viral accumulation and the onset of symptoms

Zwart, Mark Peter; Daros Arnau, Jose Antonio; Elena Fito, Santiago Fco (American Society for Microbiology, 2012)

[EN] Effective population size (N-e) is a key parameter for understanding evolutionary processes, but it is generally not considered in epidemiological studies or in studying infections of individual hosts. Whether Ne has ...
Effects of the number of genome segments on primary and systemic infection for a multipartite plant RNA virus

Sanchez Navarro, Jesus Angel; Zwart, Mark Peter; Elena Fito, Santiago Fco (American Society for Microbiology, 2013-10)

[EN] Multipartite plant viruses were discovered because of discrepancies between the observed dose response and predictions of the independent-action hypothesis (IAH) model. Theory suggests that the number of genome segments ...
Efficient escape from local optima in a highly rugged fitness landscape by evolving RNA virus populations

Cervera-Benet, Héctor; Lalic, Jasna; Elena Fito, Santiago Fco (Royal Society, The, 2016-07-17)

[EN] Predicting viral evolution has proven to be a particularly difficult task, mainly owing to our incomplete knowledge of some of the fundamental principles that drive it. Recently, valuable information has been provided ...
Emergence and phylodynamics of Citrus tristeza virus in Sicily, Italy

Davino, Salvatore; Willemsen, Anouk; Panno. Stefano; Davino, Mario; Catara, Antonino; Elena Fito, Santiago Fco; Rubio, Luis (Public Library of Science, 2013-06)

[EN] Citrus tristeza virus (CTV) outbreaks were detected in Sicily island, Italy for the first time in 2002. To gain insight into the evolutionary forces driving the emergence and phylogeography of these CTV populations, ...
Engineered Functional Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes

Ambros Palaguerri, Silvia; De la Iglesia Jordán, Francisca; Rosario, S.; Butkovic, Anamarija; Elena Fito, Santiago Fco (Oxford University Press, 2018)

[EN] Functional redundancy, understood as the functional overlap of different genes, is a double-edge sword. At the one side, it is thought to serve as a robustness mechanism that buffers the deleterious effect of mutations ...
Epistasia multidimensional y la rugosidad de los paisajes adaptativos y factores del huésped que determinan la eficacia viral

Cervera Benet, Héctor (Universitat Politècnica de València, 2018-03-01)

Somos conscientes de que existen claras diferencias en la organización del material hereditario en todos los organismos y que puede alterarse en escalas de tiempo relativamente cortas. En otras palabras, nos referimos a ...
Epistasis between mutations is host-dependent for an RNA virus

Lalic ., Jasna; Elena Fito, Santiago Fco (Royal Society, The, 2012)

How, and to what extent, does the environment influence the way mutations interact? Do environmental changes affect both the sign and the magnitude of epistasis? Are there any correlations between environments in the ...
Estimation of the in vivo recombination rate for a plant RNA virus

Tromas, Nicolas; Zwart, Mark Peter; Poulain, Maite; Elena Fito, Santiago Fco (Microbiology Society, 2014)

[EN] Phylogenomic evidence suggested that recombination is an important evolutionary force for potyviruses, one of the larger families of plant RNA viruses. However, mixed-genotype potyvirus infections are marked by low ...
Evaluación del intercambio de genes entre micovirus y sus huéspedes: el caso de la proteína de la envuelta viral

Alfonso Comos, Pau (Universitat Politècnica de València, 2020-09-07)

[ES] Los micovirus son virus que infectan a hongos y son una de las clases menos conocidas de virus hasta la fecha. La gran mayoría de los micovirus identificados son virus de RNA y dentro de estos predominan aquellos de ...
Evaluación del potencial de Caenorhabditis elegans como huésped experimental de arbovirus

González Miguélez, Rubén (Universitat Politècnica de València, 2017-02-08)

[EN] So far, Caenorhabditis elegans has been used as model organism in many different fields of study, but seldom used as experimental host in virology studies. The present work seeks to evaluate the potential of the ...
Evolution and emergence of plant viruses

Elena Fito, Santiago Fco; Fraile, Aurora; García-Arena, Fernando (Elsevier (according to Zetoc), 2014)

[EN] Viruses are common agents of plant infectious diseases. During last decades, worldwide agriculture production has been compromised by a series of epidemics caused by new viruses that spilled over from reservoir species ...
Evolutionary transitions during RNA virus experimental evolution

Elena Fito, Santiago Fco (Royal Society, The, 2016-08-19)

[EN] In their search to understand the evolution of biological complexity, John Maynard Smith and Eors Szathmary put forward the notion of major evolutionary transitions as those in which elementary units get together to ...