Calleja de Juan, Lucía(Universitat Politècnica de València, 2024-04-10)
[ES] Actualmente, existe una tendencia social y medioambiental por el cuidado y bienestar personal considerando prácticas sostenibles en la cadena de fabricación y suministro. Cambios en las preferencias estéticas, mayor ...
[EN] Gelatin injectable hydrogels have attracted attention for soft tissues regeneration; however, their poor mechanical properties limit their applications. The authors present a versatile strategy to enhance mechanical ...
[EN] Cells interact mechanically with their environment, exerting mechanical forces that probe the extracellular matrix (ECM). The mechanical properties of the ECM determine cell behavior and control cell differentiation ...
Cantó Loras, Petra(Universitat Politècnica de València, 2015-01-19)
[CA] El cartílag articular és un teixit connectiu molt especialitzat present a les articulacions, que actua com amortidor suportant enormes carregues y proporcionant una superfície de lliscament de baixa fricció. Les ...
Baiget Orts, María Amparo(Universitat Politècnica de València, 2012-01-27)
The aim of this Thesis is to investigate the use of hyaluronic acid as a material for the design of scaffolds aimed at CNS regeneration. The motivation comes from the need of searching for new strategies that allow ...
Ródenas Rochina, Joaquín; Kelly, Daniel John; Gómez Ribelles, José Luís; Lebourg, Myriam Madeleine(John Wiley & Sons, 2017)
[EN] Chondrogenesis of mesenchymal stem cells (MSCs) is known to be regulated by a number of environmental factors, including local oxygen levels. The hypothesis of this study is that the response of MSCs to hypoxia is ...
Alemany Ibor, Laura(Universitat Politècnica de València, 2021-07-30)
[ES] Glioblastoma multiforme (GBM) es el tumor cerebral más agresivo y letal conocido, con una media de supervivencia de 15 meses desde el diagnóstico inicial. Actualmente no existe un tratamiento farmacológico efectivo ...
Gisbert Roca, Fernando; Gil Santos, Luis; Mata Roig, Manuel; Milian Medina, Lara; Martínez-Ramos, Cristina; Monleón Pradas, Manuel(MDPI AG, 2022-05)
[EN] The gold standard for the treatment of peripheral nerve injuries, the autograft, presents several drawbacks, and engineered constructs are currently suitable only for short gaps or small diameter nerves. Here, we study ...
[EN] Cell-based liver therapies based on retrieving and steadying failed metabolic function(s) for acute and chronic diseases could be a valuable substitute for liver transplants, even though they are limited by the low ...
Poveda Reyes, Sara(Universitat Politècnica de València, 2016-03-03)
[EN] Articular cartilage is a tissue with low capacity for self-restoration due to its avascularity and low cell population. It is located on the surface of the subchondral bone covering the diarthrodial joints. Degeneration ...
[EN] Physico-chemical and mechanical properties of hyaluronic acid/carbon nanotubes nanohybrids have been correlated with the proportion of inorganic nanophase and the preparation procedure. The mass fraction of -COOH ...
Vilariño Feltrer, Guillermo; Martínez Ramos, Cristina; Monleon De la Fuente, Adrian; Vallés Lluch, Ana; Moratal Pérez, David; Barcia Albacar, Juan Antonio; Monleón Pradas, Manuel(2016)
[EN] Cell transplantation therapies in the nervous system are frequently hampered by glial scarring and cell drain from the damaged site, among others. To improve this situation, new biomaterials may be of help. Here, novel ...
Gisbert Roca, Fernando(Universitat Politècnica de València, 2022-11-18)
[ES] Actualmente las lesiones del sistema nervioso periférico que conllevan una pérdida de continuidad de los haces axonales suelen implicar secuelas de tipo permanente. Es cierto que en el sistema nervioso periférico ...
[EN] Polysaccharides are widely used as building blocks of scaffolds and hydrogels in tissue engineering, which may require their chemical modification to permit crosslinking. The goal of this study was to generate a library ...
Vaca González, Juan Jairo(Universitat Politècnica de València, 2019-05-02)
[ES] El cartílago hialino es un tejido conectivo denso con poca capacidad de auto regeneración cuando es afectado por patologías degenerativas. Por lo tanto, la estimulación eléctrica se ha propuesto como una terapia ...