Guillot Ferriols, María Teresa; García Briega, María Inmaculada; Tolosa Pardo, Laia; Costa, Carlos Miguel; Lanceros-Mendez, Senentxu; Gómez Ribelles, José Luís; Gallego Ferrer, Gloria(MDPIUniversitat Politècnica de València, 2022-10-19)
Mesenchymal stem cells (MSCs) osteogenic commitment before injection enhances bone regen-eration therapy results. Piezoelectric stimulation may be an effective cue to promote MSC pre-differentiation, and poly(vinylidene) ...
Guillot-Ferriols, María Teresa; García-Briega, María Inmaculada; Tolosa, Laia; Costa, Carlos M.; Lanceros-Méndez, Senentxu; Gómez Ribelles, José Luís; Ferrer GG(MDPI, 2022-10)
[EN] Mesenchymal stem cells (MSCs) osteogenic commitment before injection enhances bone regeneration therapy results. Piezoelectric stimulation may be an effective cue to promote MSCs pre-differentiation, and poly(vinylidene) ...
[EN] Metal ions are important effectors of protein and cell functions. Here, polyelectrolyte multilayers (PEMs) made of chitosan (Chi) and alginate (Alg) were doped with different metal ions (Ca2+, Co2+, Cu2+, and Fe3+), ...
Clara Trujillo, Sandra(Universitat Politècnica de València, 2016-09-02)
[ES] El objetivo de este trabajo ha sido la preparación, caracterización y estudio de la
viabilidad celular de matrices extracelulares sintéticas formadas por micropartículas
poliméricas que responden a campos magnéticos ...
Neto, Ana I.; Cibrao, Ana C.; Correia, Clara R.; Carvalho, Rita R.; Luz, Gisela M.; Ferrer, GG; Botelho, Gabriela; Picart, Catherine; Alves, Natalia M.; Mano, Joao F.(John Wiley & Sons, 2014-06-25)
[EN] In a marine environment, specific proteins are secreted by mussels and used as a bioglue to stick to a surface. These mussel proteins present an unusual amino acid 3,4-dihydroxyphenylalanine (known as DOPA). The ...
[EN] Multiple myeloma (MM) is a hematological malignancy in which the patient's drug resistance is one of the main clinical problems. As 2D cultures do not recapitulate the cellular microenvironment, which has a key role ...
Colomer Merino, Lucía(Universitat Politècnica de València, 2022-10-20)
[EN] Drug-induced liver injury (DILI) is a multifactorial patient-specific pathophysiological process that cannot be recapitulated in current in vitro models. DILI is one of the main reasons for drug withdrawal the development ...
Pons Andrés, Neus(Universitat Politècnica de València, 2023-06-19)
[ES] El hígado es el mayor órgano glandular del cuerpo, que desempeña una elevada cantidad de funciones vitales.
Una de las principales alteraciones asociadas a dicho órgano es la hepatotoxicidad inducida por fármacos ...
Morata Martínez, Miranda(Universitat Politècnica de València, 2018-09-18)
[EN] The cellular response to biomaterials is mediated not only by the innate material properties but also
by different parameters of the interface protein layer on the surface of materials, such as their
conformation ...
Trujillo Martínez, César(Universitat Politècnica de València, 2019-09-05)
[ES] Los avances recientes de la ingeniería tisular están explorando la liberación de factores de crecimiento, biomoléculas pequeñas e iones desde el biomaterial para conseguir diversos efectos terapéuticos tales como la ...
[EN] Ionic substitutions are a promising strategy to enhance the biological performance of calcium phosphates (CaP)
and composite materials for bone tissue engineering applications. However, systematic studies have not ...
[EN] Novel, hybrid fibrinogen/polylactic acid (FBG/PLA) nanofibers with different configuration (random vs aligned) and dimensionality (2¿D vs 3¿D environment) were used to control the overall behavior and the osteogenic ...
Vallés Lluch, Ana(Universitat Politècnica de València, 2008-12-15)
Se sintetizaron nanocompuestos híbridos en bloque de poli(etil metacrilato-co-hidroxietil acrilato) 70/30 wt%/sílice, P(EMA-co-HEA)/SiO2, con distintas proporciones de sílice hasta el 30 wt%. El procedimiento de síntesis ...
[EN] In the present study, we examined the potential of using highly porous poly(epsilon-caprolactone) (PCL)-coated hydroxyapatite (HAp) scaffold derived from cuttlefish bone for bone tissue engineering applications. The ...
[EN] In the present study, poly(epsilon-caprolactone)-coated hydroxyapatite scaffold derived from cuttlefish bone was prepared. Hydrothermal transformation of aragonitic cuttlefish bone into hydroxyapatite (HAp) was performed ...
[EN] Ionic substitutions within the hydroxyapatite lattice are a widely used approach to mimic the chemical composition of the bone mineral. In this work, Sr-substituted and Mg- and Sr-co-substituted calcium phosphate (CaP) ...
Guillot-Ferriols, María Teresa; Rodriguez-Hernandez, Jose-Carlos; Correia, D.M.; Carabineiro, S.A.C.; Lanceros-Méndez, S.; Gómez Ribelles, José Luís; Gallego Ferrer, Gloria(Elsevier BV, 2020-12)
[EN] The use of piezoelectric materials in tissue engineering has grown considerably since inherent bone piezoelectricity was discovered. Combinations of piezoelectric polymers with magnetostrictive nanoparticles (MNP) can ...
Vikingsson, Line; Antolinos Turpín, Carmen María; Gómez-Tejedor, José Antonio; Gallego Ferrer, Gloria; Gómez Ribelles, José Luís(Elsevier, 2016-04-01)
[EN] This study examines a biocompatible scaffold series of random copolymer networks P(EA-HEA) made of Ethyl Acrylate, EA, and 2-Hydroxyl Ethyl Acrylate, HEA. The P(EA-HEA) scaffolds have been synthesized with varying ...