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Mostrando ítems 1-7 de 7

Anti-diabetic and anti-obesity agent sodium tungstate enhances GCN pathway activation through Glc7p inhibition

Rodríguez Hernández, Carlos Javier; Guinovart, J.J.; Murguía, Jose R. (ElsevierWiley, 2012-02-03)

[EN] Tungstate counteracts diabetes and obesity in animal models, but its molecular mechanisms remain elusive. Our Saccharomyces cerevisiae-based approach has found that tungstate alleviated the growth defect induced by ...
Effects of online palliative care training on knowledge, attitude and satisfaction of primary care physicians

Pelayo, Marta; Cebrián, Diego; Areosa, Almudena; Agra, Yolanda; Izquierdo, Juan Vicente; Buendía García, Félix (BioMed Central, 2011)

Background: The Spanish Palliative Care Strategy recommends an intermediate level of training for primary care physicians in order to provide them with knowledge and skills. Most of the training involves face-to-face courses ...
Linkage Analysis in Usher Syndrome type I (USH1) Families from Spain

Espinós-Armero, Carmen Ángeles; Nájera, Carmen; Millán, José María; Ayuso, Carmen; Baiget, Montserrat; Pérez-Garrigues, Herminio; Rodrigo, Onofre; Vilela, Concepción; Beneyto, Magdalena (BMJ, 1998-05)

[EN] Usher syndrome (USH) is an autosomal recessive hereditary disorder characterised by congenital sensorineural hearing loss and gradual visual impairment secondary to retinitis pigmentosa (RP). The disorder is clinically ...
Nitic oxide promotes strong cytotoxicity of phenolic compounds against escherichia coli. The influence of antioxidant defenses

Urios, Amparo; López-Gresa, María Pilar; Gonzalez Más, Mª Carmen; Primo Millo, Jaime; Martínez, Alicia; Herrera, Guadalupe; Escudero, J. C.; O'Connor, Jose-Enrique; Blanco, Manuel (Elsevier, 2003-12-01)

[EN] The induction of mutagenic and cytotoxic effects by simple phenolics, including catechol (CAT), 3,4dihydroxyphenylacetic acid (DOPAC), hydroquinone (HQ), and 2,5-dihydroxyphenylacetic (homogentisic) acid (HGA), appears ...
Phenotypical features of the p.R120W mutation in the GDAP1 gene causing autosomal dominant Charcot-Marie-Tooth disease

Sivera, Rafael; Espinós-Armero, Carmen Ángeles; Vílchez, Juan J.; Mas, Fernando; Martínez-Rubio, Dolores; Chumillas, María José; Mayordomo, Fernando; Muelas, Nuria; Bataller, Luis; Palau, Francesc; Sevilla, Teresa (Blackwell Publishing, 2010-12)

[EN] Mutations in the ganglioside-induced-differentiation-associated protein 1 gene (GDAP1) can cause Charcot-Marie-Tooth (CMT) disease with demyelinating (CMT4A) or axonal forms (CMT2K and ARCMT2K). Most of these mutations ...
Probabilistic prediction of outbreaks of meningococcus W-135 infections over the next few years in Spain

Acedo Rodríguez, Luis; Burgos-Simon, Clara; Cortés, J.-C.; Villanueva Micó, Rafael Jacinto (Elsevier, 2017)

[EN] The genogroups of meningococcal and other bacteria are in competition in the ecosystem they form with the human hosts. Changes in vaccination strategies, prophylactic measures or usual habits, may also change the ...
Wonen's features and inter/intra rater agreement on mammographic density assesment in full-field digital mammograms

Perez-Gomez, Beatriz; Ruiz, Franciso; Martinez, Inmaculada; Casals, Maria; Miranda, Josefa; Sanchez-Contador, Carmen; Vidal, Carmen; Llobet Azpitarte, Rafael; Pollan, Marina; Salas, Dolores (Springer Verlag (Germany), 2012)

Measurement of mammographic density (MD), one of the leading risk factors for breast cancer, still relies on subjective assessment. However, the consistency of MD measurement in full-digital mammograms has yet to ...