Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco(Public Library of Science, 2011)
[EN] Empirical observations and theoretical studies suggest that viruses may use different replication strategies to amplify their genomes, which impact the dynamics of mutation accumulation in viral populations and ...
[EN] In general terms, robustness is the capacity of biological systems to function in spite of genetic or environmental perturbations. The small and compacted genomes and high mutation rates of RNA viruses, as well as the ...
Lafforgue, Guillaume; Martínez García, Fernando; Sardanyes Cayuela, Jose; De la Iglesia Jordán, Francisca; Niu, Qi-Wen; Lin, Shih-Shun; Sole, Ricard V.; Chua, Nam-Hai; Daros Arnau, Jose Antonio; Elena Fito, Santiago Fco(American Society for Microbiology, 2011)
A biotechnological application of artificial microRNAs (amiRs) is the generation of plants that are resistant to virus infection. This resistance has proven to be highly effective and sequence specific. However, before ...
Macia, Javier; Sole, Ricard V.; Elena Fito, Santiago Fco(Wiley, 2012-02)
[EN] Epistasis refers to the nonadditive interactions between genes in determining phenotypes. Considerable efforts have shown that, even for a given organism, epistasis may vary both in intensity and sign. Recent comparative ...