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Now showing items 1-13 of 13

A Genomewide Screen for Tolerance to Cationic Drugs Reveals Genes Important for Potassium Homeostasis in Saccharomyces cerevisiae

Barreto, Lina; Canadell, David; Petrezselyova, Silvia; Navarrete, Clara; Maresova, Lydie; Pérez Valle, Jorge; Herrera, Rito; Olier, Ivan; Giraldo, Jesus; Sychrova, Hana; Yenush, Lynne; Ramos, Jose; Arino, Joaquin (American Society for Microbiology, 2011)

[EN] Potassium homeostasis is crucial for living cells. In the yeast Saccharomyces cerevisiae, the uptake of potassium is driven by the electrochemical gradient generated by the Pma1 H +-ATPase, and this process represents ...
A permeable cuticle is associated with the release of reactive oxygen species and induction of innate immunity

L'Haridon, Floriane; Besson-Bard, Angelique; Binda, Matteo; Serrano Mateo, Mario; Abou-Mansour, Eliane; Balet, Francine; Schoonbeek, Henk-Jan; Hess, Stephane; Mir Moreno, Ricardo; Leon Ramos, Jose; Lamotte, Olivier; Metraux, Jean-Pierre (Public Library of Science, 2011)

[EN] Wounded leaves of Arabidopsis thaliana show transient immunity to Botrytis cinerea, the causal agent of grey mould. Using a fluorescent probe, histological staining and a luminol assay, we now show that reactive oxygen ...
Caracterización en neuronas corticales de una mutación de PRDX3 asociada con una ataxia cerebelosa de inicio infantil

Miquel Leal, Francisco Javier (Universitat Politècnica de València, 2021-07-29)

[ES] Las especies reactivas de oxígeno (ROS, por sus siglas en inglés reactive oxygen species) son el principal agente causante de estrés oxidativo en las células. Aunque están implicados en algunas vías de señalización ...
Defining typological process in the transformation of Turkish houses

Gokce, Duygu; Chen, Fei (Editorial Universitat Politècnica de València, 2018-04-20)

[EN] Typological process, theorised by the Italian Typological School as a continuous transformation process of types, has been frequently discussed in the field of urban morphology. It was widely acknowledged in the field ...
Desarrollo de un modelo de Markov de la componente rápida de la corriente de potasio de la aurícula humana

Cárdenas Betancourt, María Camila (Universitat Politècnica de València, 2022-10-13)

[ES] La fibrilación auricular (FA) es la arritmia cardíaca sostenida más común y se caracteriza por activaciones eléctricas rápidas y desorganizadas de las aurículas. En las últimas décadas, muchos estudios se han centrado ...
Estudio de la seguridad cardiaca de fármacos en presencia de defectos congénitos que afectan la componente rápida de la corriente de potasio utilizando poblaciones de modelos celulares

Sánchez Hernández, Claudia (Universitat Politècnica de València, 2022-09-05)

[ES] Las arritmias cardíacas son una de las causas más importantes de mortalidad en los países desarrollados. Se sabe que los defectos genéticos del paciente juegan un papel importante en la susceptibilidad a las arritmias ...
Evaluation of morphological and genetic diversity of loquat accessions grown in sicily

Marchese, F.; Costa, F.; Marra, F. P.; Quartararo, A.; Farina, V.; Reig Valor, Carmina; Agustí Fonfría, Manuel (International Society for Horticultural Science (ISHS), 2015)

In this study 20 accessions of loquat (Eriobotrya japonica Lindl.) that originated from Sicily and other countries were characterized phenotypically and genotyped using seven microsatellite markers. The microsatellites ...
Impact of a New SARS-CoV-2 Variant on the Population: A Mathematical Modeling Approach

González Parra, Gilberto; Martínez-Rodríguez, David; Villanueva Micó, Rafael Jacinto (MDPI AG, 2021-03-27)

[EN] Several SARS-CoV-2 variants have emerged around the world, and the appearance of other variants depends on many factors. These new variants might have different characteristics that can affect the transmissibility and ...
INDEHISCENT and SPATULA interact to specify carpel and valve margin tissue and thus promote seed dispersal in Arabidopsis

Girin, T.; Paicu, T.; Stephenson, P.; Fuentes, S.; Körner, E.; O'Brien, M.; Sorefan, K.; Wood, T. A.; Balanzá Pérez, Vicente; Ferrandiz Maestre, Cristina; Smyth, D.R.; Østergaard, L. (American Society of Plant Biologists, 2011-10)

[EN] Structural organization of organs in multicellular organisms occurs through intricate patterning mechanisms that often involve complex interactions between transcription factors in regulatory networks. For example, ...
Profile of the Roche cobas (R) EGFR mutation test for non-small cell lung cancer

Malapelle, Umberto; Sirera Pérez, Rafael; Jantus-Lewintre, Eloisa; Reclusa, P.; Calabuig-Farinas, S.; Blasco, Ana; Pisapia, P.; Rolfo, C.; Camps, Carlos (Taylor & Francis, 2017)

[EN] Introduction: The discovery of driver mutations in non-small cell lung cancer (NSCLC) has led to the development of genome-based personalized medicine. Fifteen to 20% of adenocarcinomas harbor an epidermal growth ...
Secuenciación del domino I del gen NS5A del virus de la hepatitis C para la detección de resistencias a antivirales de acción directa

Honrubia Belenguer, José Manuel (Universitat Politècnica de València, 2015-07-16)

[ES] Introducción. La infección por el virus de la hepatitis C (VHC) representa un problema sanitario de gran magnitud debido a (1) su elevada prevalencia ¿aproximadamente un 2% de la población española-; (2) la elevada ...
The advantages of React for creating a modern application

Kuzev, Gorazd (Universitat Politècnica de València, 2022-10-03)

[ES] Muchos frameworks de programación se están enfocando a simplificar la creación de una buena interfaz de usuario. Una de las mejores herramientas es React. Es por eso que elegí React como tema para mi TFG. React ...
The identification of KRAS mutations at codon 12 in plasma DNA is not a prognostic factor in advanced non-small cell lung cancer patients

Camps, Carlos; Jantus Lewintre, Eloisa; Cabrera, Andrea; Blasco, Ana; Sanmartin, Elena; Gallach, Sandra; Caballero, Cristina; del Pozo, Nieves; Rosell, Rafael; Guijarro, Ricardo; Sirera Pérez, Rafael (Elsevier, 2011-06)

Qualitative analysis of circulating DNA in the blood is a promising non-invasive diagnostic and prognostic tool. Our aim was to study the association between the presence of KRAS mutations at codon 12 and several clinical ...

Now showing items 1-13 of 13

Browsing by Subject "Mutation"

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Browsing by Subject "Mutation"