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Browsing by Subject "Nanomedicine"

Now showing items 1-8 of 8

A versatile drug delivery system targeting senescent cells

Muñoz-Espín, Daniel; Rovira, M.; Galiana, Irene; Giménez Morales, Cristina; Lozano-Torres, Beatriz; Páez Ribes, M.; LLanos, Susana; Chaib, Selim; Muñoz-Martín, M.; Ucero, Alvaro C.; Garaulet, G.; Mulero, F.; Dann, S.G.; VanArsdale, T.; Shields, D.J.; Bernardos Bau, Andrea; Murguía, Jose R.; Martínez-Máñez, Ramón (EMBO, 2018-09)

[EN] Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal beta-galactosidase ...
Desarrollo de conjugados polímericos para el tratamiento del cáncer de mama

Carrascosa Marzo, Rafael (Universitat Politècnica de València, 2016-06-14)

[EN] The medical application of nanotechnology holds a tremendous potential in the bettering of human health, particularly in grave chronic pathologies such as cancer. Within cancer many defective processes have been ...
Diseño racional y caracterización de nanodispositivos de sílice mesoporosa para liberación controlada en células senescentes

Blasco Carrasco, Jordi (Universitat Politècnica de València, 2017-10-10)

[ES] La senescencia celular es un estado que se caracteriza por un arresto del ciclo celular permanente y un fenotipo hipersecretor asociado. Originalmente se atribuyó al envejecimiento celular, pero hoy se sabe que puede ...
Estigmergia de nanopartículas para el tratamiento del cáncer de mama mediante senogénesis y senolisis

Esteve Moreno, Juan José (Universitat Politècnica de València, 2020-07-03)

[ES] Los últimos avances acerca de la senescencia celular ponen en evidencia su relación con un amplio rango de enfermedades entre las que se incluye el cáncer, colocando a este proceso como una potencial diana terapéutica. ...
Gated nanomaterials as delivery platform for the treatment of inflammatory disorders

García Fernández, Alba (Universitat Politècnica de València, 2020-11-08)

[ES] La presente tesis doctoral titulada "Nanomateriales con puertas moleculares como plataforma de liberación controlada de fármacos para el tratamiento de desórdenes inflamatorios" se centra la preparación y evaluación ...
Gold nanoparticles supported on nanoparticulate ceria as a powerful agent against intracellular oxidative stress

Menchón, Cristina; Martín González, Roberto; Apostolova, Nadezda; Victor, V. M.; Alvaro Rodríguez, Maria Mercedes; Herance Camacho, Jose Raul; García Gómez, Hermenegildo (Wiley-VCH Verlag, 2012-06-25)

Ceria-supported gold nanoparticles are prepared exhibiting peroxidase activity and acting as radical traps. Au/CeO2 shows a remarkable biocompatibility as demonstrated by measuring cellular viability, proliferation, and ...
Nanosistemas como tratamientos antitumorales para el cáncer colorrectal y su subpoblación de células madre del cáncer

Guerrero Quiles, Conrado (Universitat Politècnica de València, 2017-10-25)

Colorectal cancer (CRC) is the third most frequent cancer at global level. It is the second cause of cancer dead in Europe. His origin is multifactorial; it is caused due to genetic factors (such as for example inherit ...
Polyglutamic Acid-Gated Mesoporous Silica Nanoparticles for Enzyme-Controlled Drug Delivery

Tukappa, Asha; Ultimo, Amelia; De la Torre Paredes, Cristina; Pardo Vicente, María Teresa; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (American Chemical Society, 2016-08-23)

Mesoporous silica nanoparticles (MSNs) are highly attractive as supports in the design of controlled delivery systems that can act as containers for the encapsulation of therapeutic agents, overcoming common issues such ...

Now showing items 1-8 of 8

Browsing by Subject "Nanomedicine"

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Browsing by Subject "Nanomedicine"