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Browsing by Subject "Osteoarthritis"

Now showing items 1-9 of 9

Análisis de texturas en imágenes de resonancia magnética de la rodilla con el fin de determinar biomarcadores para un diagnóstico precoz de la artrosis de rodilla

Madrid Gómez, Juan (Universitat Politècnica de València, 2021-10-14)

[ES] El aumento de la esperanza de vida como consecuencia de los grandes avances que se están llevando a cabo en la medicina está directamete relacionado con un aumento de distintas enfermedades. Entre ellas se encuentra ...
Cell-free cartilage engineering approach using hyaluronic acid-polycaprolactone scaffolds: A study invivo

Lebourg, Myriam Madeleine; Martínez Díaz, S.; Garcia Giralt, Natalia; Torres Claramunt, R.; Gómez-Tejedor, José Antonio; Gómez Ribelles, José Luís; Vila Canet, G; Monllau, J.C. (SAGE Publications (UK and US), 2014-05)

Polycaprolactone scaffolds modified with cross-linked hyaluronic acid were prepared in order to establish whether a more hydrophilic and biomimetic microenvironment benefits the progenitor cells arriving from bone marrow ...
Characterization of adipose-derived mesenchymal stem cells in degenerative osteoarthritis: Cartilage repair potential in In-vivo and in-vitro studies

Meseguer Ripollés, José (Universitat Politècnica de València, 2016-05-19)

[EN] Cartilage degeneration is associated to degenerative bone and joint processes within osteoarthritis (OA). At present, OA are difficult to treat, involving very often, a partial or complete join substitution. However, ...
Emerging therapeutic agents in osteoarthritis

Alcaraz Tormo, Mª José; Guillen Salazar, Mª Isabel; Ferrándiz Manglano, Mª Luisa (Elsevier, 2019-07)

[EN] Osteoarthritis (OA) is the most common joint disorder and a leading cause of disability. Current treatments for OA can improve symptoms but do not delay the progression of disease. In the last years, much effort has ...
Extracellular Vesicles from Mesenchymal Stem Cells as Novel Treatments for Musculoskeletal Diseases

ALCARAZ TORMO, Mª JOSE; Compañ, Álvaro; Guillem Salazar, Mª Isabel (MDPI, 2019)

[EN] Mesenchymal stem/stromal cells (MSCs) represent a promising therapy for musculoskeletal diseases. There is compelling evidence indicating that MSC effects are mainly mediated by paracrine mechanisms and in particular ...
Extracellular vesicles: A new therapeutic strategy for joint conditions

Tofiño-Vian, Miguel; Guillen Salazar, Mª Isabel; Alcaraz Tormo, Mª Jose (Elsevier, 2018)

[EN] Extracellular vesicles (EVs) are attracting increasing interest since they might represent a more convenient therapeutic tool with respect to their cells of origin. In the last years much time and effort have been ...
Importancia de los sinoviocitos en la osteoartritis y diagnóstico de la enfermedad

Pardo Martínez, María (Universitat Politècnica de València, 2021-09-03)

[ES] La osteoartritis es una enfermedad compleja y multifactorial que afecta a las articulaciones y tiene un impacto negativo en la calidad de vida del paciente que la padece. En la fisiopatología de la enfermedad participan ...
Microvesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells as a New Protective Strategy in Osteoarthritic Chondrocytes

Tofiño-Vian, Miguel; Guillen Salazar, Mª Isabel; Perez del Caz, M.D.; Silvestre, A.; Alcaraz Tormo, Mª Jose (S. Karger AG, 2018)

[EN] Background/Aims: Chronic inflammation contributes to cartilage degeneration during the progression of osteoarthritis (OA). Adipose tissue-derived mesenchymal stem cells (ADMSC) show great potential to treat inflammatory ...
Nrf2 as a therapeutic target for rheumatic diseases

Ferrandiz Manglano, Mª Luisa; Nacher-Juan, Josep; Alcaraz Tormo, Mª Jose (Elsevier, 2018-06)

[EN] Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a master regulator of cellular protective processes. Rheumatic diseases are chronic conditions characterized by inflammation, pain, tissue damage and limitations ...