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Now showing items 1-7 of 7

Cell-free cartilage engineering approach using hyaluronic acid-polycaprolactone scaffolds: A study invivo

Lebourg, Myriam Madeleine; Martínez Díaz, S.; Garcia Giralt, Natalia; Torres Claramunt, R.; Gómez-Tejedor, José Antonio; Gómez Ribelles, José Luís; Vila Canet, G; Monllau, J.C. (SAGE Publications (UK and US), 2014-05)

Polycaprolactone scaffolds modified with cross-linked hyaluronic acid were prepared in order to establish whether a more hydrophilic and biomimetic microenvironment benefits the progenitor cells arriving from bone marrow ...
Characterization of adipose-derived mesenchymal stem cells in degenerative osteoarthritis: Cartilage repair potential in In-vivo and in-vitro studies

Meseguer Ripollés, José (Universitat Politècnica de València, 2016-05-19)

[EN] Cartilage degeneration is associated to degenerative bone and joint processes within osteoarthritis (OA). At present, OA are difficult to treat, involving very often, a partial or complete join substitution. However, ...
Emerging therapeutic agents in osteoarthritis

Alcaraz Tormo, Mª José; Guillen Salazar, Mª Isabel; Ferrándiz Manglano, Mª Luisa (Elsevier, 2019-07)

[EN] Osteoarthritis (OA) is the most common joint disorder and a leading cause of disability. Current treatments for OA can improve symptoms but do not delay the progression of disease. In the last years, much effort has ...
Extracellular Vesicles from Mesenchymal Stem Cells as Novel Treatments for Musculoskeletal Diseases

ALCARAZ TORMO, Mª JOSE; Compañ, Álvaro; Guillem Salazar, Mª Isabel (MDPI, 2019)

[EN] Mesenchymal stem/stromal cells (MSCs) represent a promising therapy for musculoskeletal diseases. There is compelling evidence indicating that MSC effects are mainly mediated by paracrine mechanisms and in particular ...
Extracellular vesicles: A new therapeutic strategy for joint conditions

Tofiño-Vian, Miguel; Guillen Salazar, Mª Isabel; Alcaraz Tormo, Mª Jose (Elsevier, 2018)

[EN] Extracellular vesicles (EVs) are attracting increasing interest since they might represent a more convenient therapeutic tool with respect to their cells of origin. In the last years much time and effort have been ...
Microvesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells as a New Protective Strategy in Osteoarthritic Chondrocytes

Tofiño-Vian, Miguel; Guillen Salazar, Mª Isabel; Perez del Caz, M.D.; Silvestre, A.; Alcaraz Tormo, Mª Jose (S. Karger AG, 2018)

[EN] Background/Aims: Chronic inflammation contributes to cartilage degeneration during the progression of osteoarthritis (OA). Adipose tissue-derived mesenchymal stem cells (ADMSC) show great potential to treat inflammatory ...
Nrf2 as a therapeutic target for rheumatic diseases

Ferrandiz Manglano, Mª Luisa; Nacher-Juan, Josep; Alcaraz Tormo, Mª Jose (Elsevier, 2018-06)

[EN] Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a master regulator of cellular protective processes. Rheumatic diseases are chronic conditions characterized by inflammation, pain, tissue damage and limitations ...

Now showing items 1-7 of 7

Browsing by Subject "Osteoarthritis"

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Browsing by Subject "Osteoarthritis"