One-pot synthesis of laurolactam from cyclododecene and air
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https://riunet.upv.es/handle/10251/233115
Cita bibliográfica
Hervàs-Arnandis, Susi;Rodríguez-Nuévalos, Silvia;Oliver-Meseguer, Judit;Leyva Perez, Antonio (2026). One-pot synthesis of laurolactam from cyclododecene and air. Catalysis Science & Technology. 16(1):96-100. https://doi.org/10.1039/D5CY01180A
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Resumen
[EN] Laurolactam is an essential compound for the synthesis of polyamides and requires four separated steps for its industrial production, starting from cyclododecane. Here we show a one-pot synthesis of laurolactam from cyclododecene, without intermediate purifications, in 66% yield. If desired, the intermediate cyclododecanone oxime can also be isolated, and the procedure is applicable for the production of caprylolactam.
Fuente
Catalysis Science & Technology issn: 2044-4753