One-pot synthesis of laurolactam from cyclododecene and air

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dc.contributor.affiliationInstituto Universitario Mixto de Tecnología Química
dc.contributor.authorHervàs-Arnandis, Susi
dc.contributor.authorRodríguez-Nuévalos, Silvia
dc.contributor.authorOliver-Meseguer, Judit
dc.contributor.authorLeyva Perez, Antonio
dc.contributor.funderAgencia Estatal de Investigaciónes_ES
dc.contributor.funderMinisterio de Ciencia e Innovaciónes_ES
dc.contributor.funderAgència Valenciana de la Innovacióes_ES
dc.contributor.funderUniversitat Politècnica de Valènciaes_ES
dc.date.accessioned2026-03-04T08:13:26Z
dc.date.available2026-03-04T08:13:26Z
dc.date.issued2026-01-12es_ES
dc.description.abstract[EN] Laurolactam is an essential compound for the synthesis of polyamides and requires four separated steps for its industrial production, starting from cyclododecane. Here we show a one-pot synthesis of laurolactam from cyclododecene, without intermediate purifications, in 66% yield. If desired, the intermediate cyclododecanone oxime can also be isolated, and the procedure is applicable for the production of caprylolactam.en_EN
dc.description.accrualMethodSes_ES
dc.description.bibliographicCitationHervàs-Arnandis, Susi;Rodríguez-Nuévalos, Silvia;Oliver-Meseguer, Judit;Leyva Perez, Antonio (2026). One-pot synthesis of laurolactam from cyclododecene and air. Catalysis Science & Technology. 16(1):96-100. https://doi.org/10.1039/D5CY01180Aes_ES
dc.description.issue1es_ES
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dc.description.sponsorshipFinancial support by project PID2023-148441NB-I00, the Severo Ochoa Centre of Excellence program (CEX2021-001230- S, both from MCIINN), and INNEST/2022/20 (from Agència Valenciana de la Innovació, Generalitat Valenciana) are gratefully acknowledged. S. H.-A. thanks ITQ (UPV-CSIC) for the concession of a contract (FPI-2022-S2-42040). S. R.-N. thanks Agència Valenciana de la Innovació for a contract. J. O.-M. thanks the MICIIN for the concession of the Ramón y Cajal contract RYC2022-036154-I (funded by MCIN/AEI/ 10.13039/501100011033). We thank Dr M. Boronat for unvaluable helping during the DFT calculations.es_ES
dc.description.upvformatpfin100es_ES
dc.description.upvformatpinicio96es_ES
dc.description.volume16es_ES
dc.identifier.doi10.1039/D5CY01180Aes_ES
dc.identifier.issn2044-4753es_ES
dc.identifier.urihttps://riunet.upv.es/handle/10251/233115
dc.languageIngléses_ES
dc.publisherThe Royal Society of Chemistryes_ES
dc.relation.ispartofCatalysis Science & Technologyes_ES
dc.relation.pasarelaS\574146es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2023-148441NB-I00/ES/NANORREACTORES SOLIDOS MODULABLES A ESCALA DE SUB-ANGSTROMS PARA REACCIONES ORGANICAS REGIO-IRREGULARES/es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/UPV//FPI-2022-S2-42040/es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/AVI//INNEST%2F2022%2F20/es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI//CEX2021-001230-S/es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/MICINN//RYC2022-036154-I/es_ES
dc.relation.publisherversionhttps://doi.org/10.1039/D5CY01180Aes_ES
dc.rightsReconocimiento - No comercial (by-nc)es_ES
dc.rights.accessRightsAbiertoes_ES
dc.subjectLaurolactam synthesises_ES
dc.subjectOne-pot reactiones_ES
dc.subjectCyclododecenees_ES
dc.subjectPolyamide precursorses_ES
dc.subjectGreen chemistryes_ES
dc.subjectCaprylolactames_ES
dc.titleOne-pot synthesis of laurolactam from cyclododecene and aires_ES
dc.typeArtículoes_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
dspace.entity.typePublicationes_ES
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