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Use of a multi-vial mathematical model to design freeze-drying cycles for pharmaceuticals at known risk of failure

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Use of a multi-vial mathematical model to design freeze-drying cycles for pharmaceuticals at known risk of failure

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Scutellà, B.; Trelea, IC.; Bourlés, E.; Fonseca, F.; Passot, S. (2018). Use of a multi-vial mathematical model to design freeze-drying cycles for pharmaceuticals at known risk of failure. En IDS 2018. 21st International Drying Symposium Proceedings. Editorial Universitat Politècnica de València. 315-322. https://doi.org/10.4995/IDS2018.2018.7421

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/118580

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Título: Use of a multi-vial mathematical model to design freeze-drying cycles for pharmaceuticals at known risk of failure
Autor: Scutellà, Bernadette Trelea, Ioan Cristian Bourlés, Erwan Fonseca, Fernanda Passot, Stephanie
Fecha difusión:
Resumen:
[EN] Freeze-drying is a dehydration method suitable for the stabilization of heat-labile pharmaceutical products, such as vaccines. Due to the vial-to-vial variability of heat and mass transfer during the process, the value ...[+]
Palabras clave: Drying , Dehydration , Dewatering , Emerging technologies , Products quality , Process control , Environmental , Evaporation , Sublimation , Diffusion , Energy , Intensification , Lyophilization , Vaccines , Heat and mass transfer , Mathematical modeling , Design space
Derechos de uso: Reserva de todos los derechos
ISBN: 9788490486887
Fuente:
IDS 2018. 21st International Drying Symposium Proceedings.
DOI: 10.4995/IDS2018.2018.7421
Editorial:
Editorial Universitat Politècnica de València
Versión del editor: http://ocs.editorial.upv.es/index.php/IDS/ids2018/paper/view/7421
Título del congreso: 21st International Drying Symposium
Lugar del congreso: Valencia, Spain
Fecha congreso: Septiembre 11-14, 2018
Agradecimientos:
This work was sponsored by GlaxoSmithKline Biologicals SA which was involved in all stages of the study conduct and analysis
Tipo: Capítulo de libro Comunicación en congreso

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