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Mechanical unfolding of long human telomeric RNA (TERRA)

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Mechanical unfolding of long human telomeric RNA (TERRA)

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Garavís, M.; Bocanegra, R.; Herrero-Galán, E.; González, C.; Villasante, A.; Arias-Gonzalez, JR. (2013). Mechanical unfolding of long human telomeric RNA (TERRA). Chemical Communications. 49(57):6397-6399. https://doi.org/10.1039/c3cc42981d

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Título: Mechanical unfolding of long human telomeric RNA (TERRA)
Autor: Garavís, M. Bocanegra, R. Herrero-Galán, E. González, C. Villasante, A. Arias-Gonzalez, J. R.
Entidad UPV: Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada
Fecha difusión:
Resumen:
[EN] We report the first single molecule investigation of TERRA molecules. By using optical-tweezers and other biophysical techniques, we have found that long RNA constructions of up to 25 GGGUUA repeats form higher order ...[+]
Palabras clave: G-quadruplex , TERRA , Single-molecule , Optical tweezers , Unfolding , Stability
Derechos de uso: Reserva de todos los derechos
Fuente:
Chemical Communications. (issn: 1359-7345 )
DOI: 10.1039/c3cc42981d
Editorial:
The Royal Society of Chemistry
Versión del editor: https://doi.org/10.1039/c3cc42981d
Código del Proyecto:
info:eu-repo/grantAgreement/MEC//RYC-2007-01765/ES/RYC-2007-01765/
info:eu-repo/grantAgreement/Gobierno de la Comunidad de Madrid//S2009%2FMAT-1507/ES/Nuevos materiales y dispositivos biofuncionales híbridos en nanociencia/
info:eu-repo/grantAgreement/MICINN//BFU2011-30295-C02-01/ES/ESTUDIO MULTIDISCIPLINAR PARA DESENTRAÑAR LOS MECANISMOS DEL COMPORTAMIENTO CROMOSOMICO: DE LA ESTRUCTURA DEL RNA A LA DINAMICA CROMOSOMICA./
info:eu-repo/grantAgreement/MICINN//CTQ2010-21567-C02-02/ES/ESTRUCTURA, SOLVATACION Y UNION DE LIGANDOS DE ARNES Y PROTEINAS CON CONFORMACIONES MALIGNAS MEDIANTE RMN/
info:eu-repo/grantAgreement/MICINN//BES-2009-027909-2/ES/BES-2009-027909-2/
Agradecimientos:
This work was supported by grants from the Spanish Ministry of Science and Innovation (grants RYC2007-01765 to JRA-G, BFU2011-30295-C02-01 to AV, and CTQ2010-21567-C02-02 to CG). MG was supported by the FPI fellowship ...[+]
Tipo: Artículo

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