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Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes

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Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes

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Bergues-Pupo, A.; Arias-Gonzalez, JR.; Moron, M.; Fiasconaro, A.; Falo, F. (2015). Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes. Nucleic Acids Research. 43(15):7638-7647. https://doi.org/10.1093/nar/gkv690

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Título: Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes
Autor: Bergues-Pupo, A.E. Arias-Gonzalez, J. R. Moron, M.C. Fiasconaro, A. Falo, F.
Entidad UPV: Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada
Fecha difusión:
Resumen:
[EN] Cations are known to mediate diverse interactions in nucleic acids duplexes but they are critical in the arrangement of four-stranded structures. Here, we use all- atom molecular dynamics simulations with explicit ...[+]
Palabras clave: G-quadruplex , DNA , RNA , Cation , Stability , Molecular dynamics
Derechos de uso: Reconocimiento (by)
Fuente:
Nucleic Acids Research. (issn: 0305-1048 )
DOI: 10.1093/nar/gkv690
Editorial:
Oxford University Press
Versión del editor: https://doi.org/10.1093/nar/gkv690
Código del Proyecto:
info:eu-repo/grantAgreement/MINECO//MAT2013-49455-EXP/ES/G-CUADRUPLEX COMO INTERRUPTOR MOLECULAR CONTROLADO POR NANOPARTICULAS Y DEMOSTRADO POR PINZAS OPTICAS/
info:eu-repo/grantAgreement/UKRI//EP%2FK020633%2F1/GB/GALE - Global Accessibility to Local Experience/
info:eu-repo/grantAgreement/MICINN//FIS2011-25167/ES/REDES, BIOFISICA Y CIENCIA NO LINEAL/
info:eu-repo/grantAgreement/MINECO//FIS2014-55867-P/ES/SOCIOBIOTEC: FISICA ESTADISITCA Y NO LINEAL APLICADA A SISTEMAS SOCIALES, BIOLOGICOS Y TECNOLOGICOS/
info:eu-repo/grantAgreement/Gobierno de Aragón//E19/ES/Fisica Estadistica y No Lineal (GEFENOL)/
Agradecimientos:
This work was supported by the Spanish DGICYT Projects No. FIS2011-25167 and FIS2014-55867-P, co-financed by FEDER funds, and by the Gobierno de Aragon through the grant E19 to the FENOL group. Work by J.R. A-G. is supported ...[+]
Tipo: Artículo

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