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The MATH-BTB BPM3 and BPM5 subunits of Cullin3-RING E3 ubiquitin ligases target PP2CA and other clade A PP2Cs for degradation

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The MATH-BTB BPM3 and BPM5 subunits of Cullin3-RING E3 ubiquitin ligases target PP2CA and other clade A PP2Cs for degradation

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Julian-Valenzuela, J.; Coego Gonzalez, A.; Lozano Juste, J.; Lechner, E.; Wu, Q.; Zhang, X.; Merilo, E.... (2019). The MATH-BTB BPM3 and BPM5 subunits of Cullin3-RING E3 ubiquitin ligases target PP2CA and other clade A PP2Cs for degradation. Proceedings of the National Academy of Sciences. 116(31):15725-15734. https://doi.org/10.1073/pnas.1908677116

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Title: The MATH-BTB BPM3 and BPM5 subunits of Cullin3-RING E3 ubiquitin ligases target PP2CA and other clade A PP2Cs for degradation
Author: Julian-Valenzuela, Jose Coego Gonzalez, Alberto LOZANO JUSTE, JORGE Lechner, Esther Wu, Qian Zhang, Xu Merilo, Ebe Belda Palazón, Borja Park, Sang-Youl Cutler, Sean R. An, Chengcai Genschik, Pascal Rodríguez Egea, Pedro Luís
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
Issued date:
Abstract:
[EN] Early abscisic acid signaling involves degradation of clade A protein phosphatases type 2C (PP2Cs) as a complementary mechanism to PYR/PYL/RCAR-mediated inhibition of PP2C activity. At later steps, ABA induces ...[+]
Subjects: ABA , PP2Cs , BPM , CRL3 , Substrate receptor
Copyrigths: Reserva de todos los derechos
Source:
Proceedings of the National Academy of Sciences. (issn: 0027-8424 )
DOI: 10.1073/pnas.1908677116
Publisher:
Proceedings of the National Academy of Sciences
Publisher version: https://doi.org/10.1073/pnas.1908677116
Project ID:
info:eu-repo/grantAgreement/EC/H2020/707477/EU
Ministerio de Ciencia, Innovación y Universidades/BIO2017-82503-R
...[+]
info:eu-repo/grantAgreement/EC/H2020/707477/EU
Ministerio de Ciencia, Innovación y Universidades/BIO2017-82503-R
MICINN/BIO2014-52537-R
ANR/ANR-10-LABX-0036
GV/APOSTD/2017/039
Estonian Research Council/PUT1133
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Thanks:
Work in P.L.R.'s laboratory was supported by the Ministerio de Ciencia, Innovacion y Universidades (MICIU), Fondo Europeo de Desarrollo Regional, and Consejo Superior de Investigaciones Cientificas (grants BIO2014-52537-R ...[+]
Type: Artículo

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