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Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors

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Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors

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Trujillo-Muñoz, S.; González-García, C.; Rico Tortosa, PM.; Reid, A.; Windmill, J.; Dalby, MJ.; Salmerón Sánchez, M. (2020). Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors. Biomaterials. 252:1-15. https://doi.org/10.1016/j.biomaterials.2020.120104

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Title: Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors
Author: Trujillo-Muñoz, Sara González-García, Cristina Rico Tortosa, Patricia María Reid, Andrew Windmill, James Dalby, Matthew J. Salmerón Sánchez, Manuel
UPV Unit: Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada
Universitat Politècnica de València. Centro de Biomateriales e Ingeniería Tisular - Centre de Biomaterials i Enginyeria Tissular
Issued date:
[EN] Extracellular matrix (ECM)-derived matrices such as Matrigel are used to culture numerous cell types in vitro as they recapitulate ECM properties that support cell growth, organisation, migration and differentiation. ...[+]
Subjects: Hydrogels , Growth factors , Fibronectin , Poly(ethylene) glycol , Bone , Vascularisation
Copyrigths: Reconocimiento (by)
Biomaterials. (issn: 0142-9612 )
DOI: 10.1016/j.biomaterials.2020.120104
Publisher version: https://doi.org/10.1016/j.biomaterials.2020.120104
Project ID:
info:eu-repo/grantAgreement/EC/FP7/615030/EU/Soft and Small: Acoustic Transducers Inspired by Nature/
info:eu-repo/grantAgreement/UKRI//EP%2FP001114%2F1/GB/Engineering growth factor microenvironments - a new therapeutic paradigm for regenerative medicine/
info:eu-repo/grantAgreement/UKRI//MR%2FL022710%2F1/GB/Synergistic microenvironments for non-union bone defects/
This study was supported by the UK Regenerative Medicine Platform (MRC grant MR/L022710/1), the UK Engineering and Physical Sciences Research Council (EPSRC EP/P001114/1) and a programme grant from the Sir Bobby Charlton ...[+]
Type: Artículo


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