- -

In silico assessment of drug safety in human heart applied to late sodium current blockers

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

In silico assessment of drug safety in human heart applied to late sodium current blockers

Show full item record

Trenor Gomis, BA.; Gomis-Tena Dolz, J.; Cardona Urrego, KE.; Romero Pérez, L.; Rajamani, S.; Belardinelli, L.; Giles, WR.... (2013). In silico assessment of drug safety in human heart applied to late sodium current blockers. Channels. 7(4):1-14. doi:10.4161/chan.24905

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/67665

Files in this item

Item Metadata

Title: In silico assessment of drug safety in human heart applied to late sodium current blockers
Author:
UPV Unit: Universitat Politècnica de València. Instituto Interuniversitario de Investigación en Bioingeniería y Tecnología Orientada al Ser Humano - Institut Interuniversitari d'Investigació en Bioenginyeria i Tecnologia Orientada a l'Ésser Humà
Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica
Issued date:
Abstract:
Drug-induced action potential (AP) prolongation leading to Torsade de Pointes is a major concern for the development of anti-arrhythmic drugs. Nevertheless the development of improved anti-arrhythmic agents, some of which ...[+]
Subjects: Anti-arrhythmic , Drug safety , Multi-channel block , Reverse rate-dependence , Late sodium current , Transmural dispersion of repolarization
Copyrigths: Reserva de todos los derechos
Source:
Channels. (issn: 1933-6950 ) (eissn: 1933-6969 )
DOI: 10.4161/chan.24905
Publisher:
Landes Bioscience
Publisher version: http://dx.doi.org/10.4161/chan.24905
Thanks:
This work was supported by (1) Plan Nacional de Investigacion Cientifica, Desarrollo e Innovacion Tecnologica, (2) Plan Avanza en el marco de la Accion Estrategica de Telecomunicaciones y Sociedad de la Informacion del ...[+]
Type: Artículo

This item appears in the following Collection(s)

Show full item record