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Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus

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Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus

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Lalic, J.; Elena Fito, SF. (2012). Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus. Heredity. 109(2):71-77. doi:10.1038/hdy.2012.15

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/72998

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Title: Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus
Author:
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
Issued date:
Abstract:
How epistatic interactions between mutations determine the genetic architecture of fitness is of central importance in evolution. The study of epistasis is particularly interesting for RNA viruses because of their genomic ...[+]
Subjects: Epistasis , Fitness landscapes , Genome architecture , Virus evolution
Copyrigths: Cerrado
Source:
Heredity. (issn: 0018-067X )
DOI: 10.1038/hdy.2012.15
Publisher:
Nature Publishing Group
Publisher version: http://dx.doi.org/10.1038/hdy.2012.15
Thanks:
We thank Francisca de la Iglesia and Angels Prosper for their excellent technical assistance, Stephanie Bedhomme and Mark P Zwart for the discussion and Mario A Fares for statistical advice. Jose A Daros generously gifted ...[+]
Type: Artículo

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