- -

Characterization of the interaction between hepatitis C virus NS5B and the human oestrogen receptor alpha

RiuNet: Repositorio Institucional de la Universidad Politécnica de Valencia

Compartir/Enviar a

Citas

Estadísticas

  • Estadisticas de Uso

Characterization of the interaction between hepatitis C virus NS5B and the human oestrogen receptor alpha

Mostrar el registro completo del ítem

Hillung, J.; Ruiz-Lopez, E.; Bellon-Echeverria, I.; Clemente-Casares, P.; Mas, A. (2012). Characterization of the interaction between hepatitis C virus NS5B and the human oestrogen receptor alpha. Journal of General Virology. 93:780-785. https://doi.org/10.1099/vir.0.039396-0

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/76744

Ficheros en el ítem

[Cerrado]
Nombre: HILLUNG;Ruiz-Lope ...
Tamaño: 234.1Kb
Formato: PDF
Descripción: Versión editorial
Solicitar una copia al autor

Metadatos del ítem

Título: Characterization of the interaction between hepatitis C virus NS5B and the human oestrogen receptor alpha
Autor: Hillung, Julia Ruiz-Lopez, Elena Bellon-Echeverria, Itxaso Clemente-Casares, Pilar Mas, Antonio
Entidad UPV: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
Fecha difusión:
Resumen:
[EN] The RNA-dependent RNA polymerase (NS5B) of hepatitis C virus (HCV) is part of the viral replicative complex and plays a crucial role in HCV replication. It has been described that NS5B interacts with cellular proteins, ...[+]
Derechos de uso: Cerrado
Fuente:
Journal of General Virology. (issn: 0022-1317 )
DOI: 10.1099/vir.0.039396-0
Editorial:
Microbiology Society
Versión del editor: http://dx.doi.org/10.1099/vir.0.039396-0
Código del Proyecto:
info:eu-repo/grantAgreement/JCCM//PPII10-0243-6857/
info:eu-repo/grantAgreement/MICINN//BFU2010-18767/ES/INTERACCIONES PROTEINA PROTEINA COMO MODULADORAS DE LA TRANSICION INICIACION ELONGACION EN EL CICLO DE SINTESIS DE LA ARN POLIMERASA DEL VIRUS DE LA HEPATITIS C/
info:eu-repo/grantAgreement/Junta de Comunidades de Castilla-La Mancha//MOV-2006_JI%2F06/ES/MOV-2006_JI%2F06/
Agradecimientos:
Authors gratefully acknowledge Dr Watashi for providing oestrogen receptor domain C and derivative constructs. This work was supported by Consejeria de Educacion de Castilla La Mancha (grant no. PPII10-0243-6857) and ...[+]
Tipo: Artículo

References

Behrens, S. E., Tomei, L., & De Francesco, R. (1996). Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. The EMBO Journal, 15(1), 12-22. doi:10.1002/j.1460-2075.1996.tb00329.x

Bellón-Echeverría, I., López-Jiménez, A. J., Clemente-Casares, P., & Mas, A. (2010). Monitoring hepatitis C virus (HCV) RNA-dependent RNA polymerase oligomerization by a FRET-based in vitro system. Antiviral Research, 87(1), 57-66. doi:10.1016/j.antiviral.2010.04.009

Chinnaswamy, S., Yarbrough, I., Palaninathan, S., Kumar, C. T. R., Vijayaraghavan, V., Demeler, B., … Kao, C. C. (2008). A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase. Journal of Biological Chemistry, 283(29), 20535-20546. doi:10.1074/jbc.m801490200 [+]
Behrens, S. E., Tomei, L., & De Francesco, R. (1996). Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. The EMBO Journal, 15(1), 12-22. doi:10.1002/j.1460-2075.1996.tb00329.x

Bellón-Echeverría, I., López-Jiménez, A. J., Clemente-Casares, P., & Mas, A. (2010). Monitoring hepatitis C virus (HCV) RNA-dependent RNA polymerase oligomerization by a FRET-based in vitro system. Antiviral Research, 87(1), 57-66. doi:10.1016/j.antiviral.2010.04.009

Chinnaswamy, S., Yarbrough, I., Palaninathan, S., Kumar, C. T. R., Vijayaraghavan, V., Demeler, B., … Kao, C. C. (2008). A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase. Journal of Biological Chemistry, 283(29), 20535-20546. doi:10.1074/jbc.m801490200

Chinnaswamy, S., Murali, A., Li, P., Fujisaki, K., & Kao, C. C. (2010). Regulation of De Novo-Initiated RNA Synthesis in Hepatitis C Virus RNA-Dependent RNA Polymerase by Intermolecular Interactions. Journal of Virology, 84(12), 5923-5935. doi:10.1128/jvi.02446-09

Clemente-Casares, P., López-Jiménez, A. J., Bellón-Echeverría, I., Encinar, J. A., Martínez-Alfaro, E., Pérez-Flores, R., & Mas, A. (2011). De Novo Polymerase Activity and Oligomerization of Hepatitis C Virus RNA-Dependent RNA-Polymerases from Genotypes 1 to 5. PLoS ONE, 6(4), e18515. doi:10.1371/journal.pone.0018515

Flisiak, R., Feinman, S. V., Jablkowski, M., Horban, A., Kryczka, W., Pawlowska, M., … Crabbé, R. (2009). The cyclophilin inhibitor Debio 025 combined with PEG IFNα2a significantly reduces viral load in treatment-naïve hepatitis C patients. Hepatology, 49(5), 1460-1468. doi:10.1002/hep.22835

Gastaminza, P., Whitten-Bauer, C., & Chisari, F. V. (2009). Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection. Proceedings of the National Academy of Sciences, 107(1), 291-296. doi:10.1073/pnas.0912966107

Georgel, P., Schuster, C., Zeisel, M. B., Stoll-Keller, F., Berg, T., Bahram, S., & Baumert, T. F. (2010). Virus–host interactions in hepatitis C virus infection: implications for molecular pathogenesis and antiviral strategies. Trends in Molecular Medicine, 16(6), 277-286. doi:10.1016/j.molmed.2010.04.003

Gerold, G., & Rice, C. M. (2011). Locking out hepatitis C. Nature Medicine, 17(5), 542-544. doi:10.1038/nm0511-542

Guedj, J., Rong, L., Dahari, H., & Perelson, A. S. (2010). A perspective on modelling hepatitis C virus infection. Journal of Viral Hepatitis, 17(12), 825-833. doi:10.1111/j.1365-2893.2010.01348.x

Hayashida, K., Shoji, I., Deng, L., Jiang, D.-P., Ide, Y.-H., & Hotta, H. (2010). 17β-estradiol inhibits the production of infectious particles of hepatitis C virus. Microbiology and Immunology, 54(11), 684-690. doi:10.1111/j.1348-0421.2010.00268.x

Khattab, M. A. (2009). Targeting host factors: A novel rationale for the management of hepatitis C virus. World Journal of Gastroenterology, 15(28), 3472. doi:10.3748/wjg.15.3472

Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., … Evans, R. M. (1995). The nuclear receptor superfamily: The second decade. Cell, 83(6), 835-839. doi:10.1016/0092-8674(95)90199-x

Nagy, P. D., Wang, R. Y., Pogany, J., Hafren, A., & Makinen, K. (2011). Emerging picture of host chaperone and cyclophilin roles in RNA virus replication. Virology, 411(2), 374-382. doi:10.1016/j.virol.2010.12.061

Paeshuyse, J., Kaul, A., De Clercq, E., Rosenwirth, B., Dumont, J.-M., Scalfaro, P., … Neyts, J. (2006). The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replicationin vitro. Hepatology, 43(4), 761-770. doi:10.1002/hep.21102

Qin, W., Luo, H., Nomura, T., Hayashi, N., Yamashita, T., & Murakami, S. (2001). Oligomeric Interaction of Hepatitis C Virus NS5B Is Critical for Catalytic Activity of RNA-dependent RNA Polymerase. Journal of Biological Chemistry, 277(3), 2132-2137. doi:10.1074/jbc.m106880200

Ranjith-Kumar, C. T., Kim, Y.-C., Gutshall, L., Silverman, C., Khandekar, S., Sarisky, R. T., & Kao, C. C. (2002). Mechanism of De Novo Initiation by the Hepatitis C Virus RNA-Dependent RNA Polymerase: Role of Divalent Metals. Journal of Virology, 76(24), 12513-12525. doi:10.1128/jvi.76.24.12513-12525.2002

Vidalain, P.-O., & Tangy, F. (2010). Virus-host protein interactions in RNA viruses. Microbes and Infection, 12(14-15), 1134-1143. doi:10.1016/j.micinf.2010.09.001

Watashi, K., Ishii, N., Hijikata, M., Inoue, D., Murata, T., Miyanari, Y., & Shimotohno, K. (2005). Cyclophilin B Is a Functional Regulator of Hepatitis C Virus RNA Polymerase. Molecular Cell, 19(1), 111-122. doi:10.1016/j.molcel.2005.05.014

Watashi, K., Inoue, D., Hijikata, M., Goto, K., Aly, H. H., & Shimotohno, K. (2007). Anti-hepatitis C Virus Activity of Tamoxifen Reveals the Functional Association of Estrogen Receptor with Viral RNA Polymerase NS5B. Journal of Biological Chemistry, 282(45), 32765-32772. doi:10.1074/jbc.m704418200

Winkler, C. A. (2008). Identifying Host Targets for Drug Development with Knowledge from Genome-wide Studies: Lessons from HIV-AIDS. Cell Host & Microbe, 3(4), 203-205. doi:10.1016/j.chom.2008.04.001

Zacharias, D. A. (2002). Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells. Science, 296(5569), 913-916. doi:10.1126/science.1068539

[-]

recommendations

 

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro completo del ítem