[EN] To get an insight into the host RNA silencing defense induced by Citrus tristeza virus (CTV) and into the counter defensive reaction mediated by its three silencing suppressors (p25, p20 and p23), we have examined by ...
[EN] To dissect the host RNA silencing response incited by citrus tristeza virus (CTV, genus Closterovirus), a (+) ssRNA of similar to 19300 nt, and the counter reaction deployed by the virus via its three RNA silencing ...
Di Serio, Francesco; De Stradis, Angelo; Delgado Villar, Sonia Guadalupe; Flores Pedauye, Ricardo; Navarro, Beatriz(Frontiers Media, 2013-01-07)
[EN] Viroids are infectious agents identified only in plants so far. In contrast to viruses, the genome of viroids is composed of a tiny circular RNA (250-400 nt) not coding for proteins, but containing in its compact ...
Minoia, Sofia(Universitat Politècnica de València, 2015-03-31)
Los viroides, los agentes infecciosos más simples de la escala biológica, están constituidos por
una molécula circular de RNA monocatenario de aproximadamente 250-400 nucleótios (nt) que no
codifica proteína alguna. A ...
[EN] Viroids, the smallest infectious agents endowed with autonomous replication, are tiny single-stranded circular RNAs (similar to 250 to 400 nt) without protein-coding ability that, despite their simplicity, infect and ...
Delgado Villar, Sonia Guadalupe; Navarro, Beatriz; Serra, Pedro; Gentit, Pascal; Cambra, Miguel Ángel; Chiumenti, Michela; De Stradis, Angelo; Di Serio, Francesco; FLORES PEDAUYE, RICARDO(Landes Bioscience, 2019-07-03)
[EN] Understanding how viruses and subviral agents initiate disease is central to plant pathology. Whether RNA silencing mediates the primary lesion triggered by viroids (small non-protein-coding RNAs), or just intermediate-late ...
[EN] Members of the family Avsunviroidae have a single-stranded circular RNA genome that adopts a rod-like or branched conformation and can form, in the strands of either polarity, hammerhead ribozymes involved in their ...
Di Serio, Francesco; Owens, Robert A.; Li, Shi-Fang; Matousek, Jaroslav; Pallás Benet, Vicente; Randles, John W.; Sano, Teruo; Verhoeven, Jacobus Th. J.; Vidalakis, Georgios; FLORES PEDAUYE, RICARDO(Microbiology Society, 2021)
[EN] Members of the family Pospiviroidae have single-stranded circular RNA genomes that adopt a rod-like or a quasi-rod-like conformation. These genomes contain a central conserved region that is involved in replication ...
Minoia, Sofia(Universitat Politècnica de València, 2011-09-06)
Los viroides son pequeños RNAs circulares que no codifican proteína alguna. Las infecciones causadas por viroides en plantas inducen la acumulación de pequeños RNAs viroidales (vd-sRNAs) de 21-24 nt que presentan características ...
Pallás Benet, Vicente; HERNANDEZ FORT, CARMEN; Marcos, Jose F.; Daròs, José-Antonio; Ambrós, Silvia; Navarro, Beatriz; NAVARRO BOHIGUES, JOSE ANTONIO; La Peña Del Rivero, Marcos De; Gago-Zachert, Selma; Gas, Maria E.; CARBONELL, ALBERTO; López Del Rincón, Carmelo; Martínez-De Alba, Angel E.; Di Serio, Francesco; Moreno, Pedro(Elsevier, 2022-04-15)
[EN] Ricardo Flores (1947-2020) focused his research on the identification, replication, pathogenesis, and evolution of viroids, the minimal non-protein-coding circular RNAs (250-400 nt) able to replicate and incite diseases ...
[EN] In the 90 ' s, pear blister canker viroid (PBCVd), apple dimple fruit viroid (ADFVd), peach latent mosaic viroid (PLMVd) and chrysanthemum chlorotic mottle viroid (CChMVd) were identified and characterized in the ...
[EN] Composed of a few hundreds of nucleotides, viroids are infectious, circular, non-protein coding RNAs able to usurp plant cellular enzymes and molecular machineries to replicate and move in their hosts. Several secondary ...
Di Serio, Francesco; Owens, Robert A.; Navarro, Beatriz; Serra, Pedro; Martínez De Alba, Angel Emilio; Delgado Villar, Sonia Guadalupe; CARBONELL, ALBERTO; Gago-Zachert, Selma(Elsevier, 2023-01-02)
[EN] Viroids are small, single-stranded, non-protein coding and circular RNAs able to infect host plants in the absence of any helper virus. They may elicit symptoms in their hosts, but the underlying molecular pathways ...
Navarro, B; Gisel, A; Rodio, Maria Elena; Delgado Villar, Sonia Guadalupe; Flores Pedauye, Ricardo; Di Serio, Francesco(Wiley, 2012-06)
[EN] How viroids, tiny non-protein-coding RNAs (250–400 nt), incite disease is unclear. One hypothesis is that
viroid-derived small RNAs (vd-sRNAs; 21–24 nt) resulting from the host defensive response, via RNA silencing,
may ...
Serra, Pedro; CARBONELL, ALBERTO; Navarro, Beatriz; Gago Zachert, Selma; Li, Shigang; Di Serio, Francesco; FLORES PEDAUYE, RICARDO(Proceedings of the National Academy of Sciences, 2020-05-12)
[EN] Viroids are tiny infectious agents of plants, consisting exclusively of a small (246–401 nucleotides)
circular RNA lacking protein-coding ability. Likely mimicking structural features of cellular RNAs,
they can ...
[EN] Composed of a naked circular non-protein-coding genomic RNA, counting only a few hundred nucleotides, viroids¿the smallest infectious agents known so far¿are able to replicate and move systemically in herbaceous and ...
Minoia, Sofia; Navarro, B; Delgado Villar, Sonia Guadalupe; Di Serio, Francesco; Flores Pedauye, Ricardo(Oxford University Press (OUP), 2015-02-27)
[EN] While biogenesis of viroid RNAs is well-known, how they decay is restricted to data involving host RNA silencing. Here we report an alternative degradation pathway operating on potato spindle tuber viroid (PSTVd), the ...