Pharmacological treatment of several diseases, such as attention-deficit hyperactivity disorder (ADHD), presents marked variability in efficiency and its adverse effects. The genotyping of specific single nucleotide ...
Morais Ezquerro, Sergi Beñat; Atienza Boronat, Mª Julia; Herrero Villen, María Asunción; Noguera Murray, Patricia Silvestre; Tortajada Genaro, Luis Antonio(Universitat Politècnica de València, 2018-06-19)
En Química, como en cualquier ciencia experimental, cuando hablamos de incertidumbre de una medida se usan diferentes términos para describir la confianza de los resultados obtenidos y se establecen reglas para expresarlos ...
[EN] This paper shows the influence of different sample storage protocols, on the chemiluminescence signal of some metal ions. The storage protocols studied were: acid addition (HCl or HNO3) and no reagent addition to ...
Santiago Felipe, Sara(Universitat Politècnica de València, 2015-10-26)
[EN] Food security is guaranteed when there is sufficient, safe and nutritious food. This assurance must be satisfied throughout the entire production process, which is known as "safety from farm to fork". This results in ...
Santiago Felipe, Sara; Tortajada-Genaro, Luis Antonio; Morais, Sergi; Puchades, Rosa; Maquieira Catala, Ángel(Elsevier, 2015-05-01)
[EN] A valid solution for micro-analytical systems is the selection of a compatible amplification reaction with a
simple, highly-integrated efficient design that allows the detection of multiple genomic targets. Two
...
Tortajada-Genaro, Luis Antonio; Santiago Felipe, Sara; Amasia, Mary; Russom, Aman; Maquieira Catala, Ángel(Royal Society of Chemistry, 2015)
[EN] A new advancement in massive DNA-based screening in limited-resource settings is demonstrated through the incorporation of easy-to-fabricate microfluidic chambers on digital versatile discs (DVDs) to perform isothermal ...
Yamanaka, Eric Seiti(Universitat Politècnica de València, 2020-07-21)
[EN] The determination of genetic biomarkers is progressively becoming more extended and popular, being commercialized even in kits for personalized medicine. Establishing specific genotype variations for each patient, ...
[ES] Los sistemas sensores basados en La tecnología de
disco compacto consisten en un conjunto deanálisis
de micromatrices que integra el reconocimiento
molecular en La superficie de un disco compacto
estándar. en este ...
YAMANAKA, ERIC-SEITI; Tortajada-Genaro, Luis Antonio; Maquieira, A.(Springer-Verlag, 2017-05)
[EN] The costs of current genotyping methods limit their application to personalized therapy. The authors describe an alternative approach for the detection of single-point-polymorphisms using recombinant polymerase ...
Martorell-Tejedor, Sara; Tortajada-Genaro, Luis Antonio; Maquieira Catala, Angel(Elsevier, 2019-12-27)
[EN] The studied challenge is the specific detection of low-abundant genomic variants that differ by a single nucleotide from the wild type. The combination of blocked recombinase polymerase amplification (RPA) and selective ...
León Sala, Teresa(Universitat Politècnica de València, 2015-10-22)
[EN] Oral anticoagulants are chronically taken by 1% and 2% of the population of the developed world. The most important is the warfarin (4-hydroxy-3-(3-oxo-1-phenylbutyl)-coumarin) because their effectiveness for ...
[EN] Highly portable, cost-effective, and rapid-response devices are required for the subtyping of the most frequent food-borne bacteria; thereby the sample rejection strategies and hygienization techniques along the food ...
Tortajada-Genaro, Luis Antonio(Hipatia Press, 2022-02-15)
[EN] The formative assessment is a strategy that allows students to be aware of the state of their learning and to establish ways to correct the identified deficiencies; at the same time, it provides information to the ...
Tortajada-Genaro, Luis Antonio; Maquieira Catala, Ángel(Elsevier, 2021-10)
[EN] The identification of different transgenic products that are potentially present in foods is a priority given their
impact on environmental safeness and health care. In this context, reliable, fast and inexpensive ...
Tortajada Genaro, Luis Antonio; Santiago Felipe, Sara; Morais Ezquerro, Sergi Beñat; GABALDÓN, JOSE ANTONIO; Puchades Pla, Rosa; Maquieira Catala, Ángel(American Chemical Society, 2012-01-11)
The development of a DNA microarray method on a digital versatile disk (DVD) is described for the simultaneous detection of traces of hazelnut (Corylus avellana L.), peanut (Arachis hypogaea), and soybean (Glycine max) in ...
Campins-Falcó, P.; Tortajada-Genaro, Luis Antonio; Meseguer-Lloret, S.; Bosch-Reig, F.(Springer-Verlag, 2002)
[EN] The simultaneous determination of chromium and cobalt in water samples has been studied. Chemiluminescence registers based on the luminol-hydrogen peroxide reaction have obtained by a batch procedure. PLS algorithms ...
López Jareño, Aurora(Universitat Politècnica de València, 2020-10-06)
[ES] El presente trabajo consiste en una revisión bibliográfica enfocada a analizar y comparar las diferentes estrategias colorimétricas basadas en la interacción de los ácidos nucleicos con las nanopartículas de oro.
En ...
Santiago Felipe, Sara; Tortajada-Genaro, Luis Antonio; Morais, Sergi; Puchades, Rosa; Maquieira Catala, Ángel(Elsevier, 2014-12-01)
[EN] An integrated sensor comprising isothermal DNA amplification and in situ detection is presented. The method principle is based on recombinase polymerase amplification (RPA) and detection in the microarray format by ...
Santiago Felipe, Sara; Tortajada-Genaro, Luis Antonio; Puchades, Rosa; Maquieira Catala, Ángel(Springer Verlag (Germany), 2016-03)
An integrated method for the parallelized detection of multiple DNA target sequences is presented by using microstructures in a digital versatile disc (DVD). Samples and reagents were managed by using both the capillary ...