[EN] The purpose of this project is to develop and validate a Deep Learning (DL) FDG PET imaging algorithm able to identify patients with any neurodegenerative diseases (Alzheimer's Disease (AD), Frontotemporal Degeneration ...
Eskildsen, Simon F.; Coupé, Pierrick; Fonov, Vladimir; Manjón Herrera, José Vicente; Leung, Kelvin K.; Guizard, Nicolas; Wassef, Shafik N.; Østergaard, Lasse Riis; Collins, D. Louis; Alzheimer's Dis Neuroimaging(Elsevier, 2012-02-01)
Brain extraction is an important step in the analysis of brain images. The variability in brain morphology and the difference in intensity characteristics due to imaging sequences make the development of a general purpose ...
[EN] Brain imaging studies have shown that slow and progressive cerebral atrophy characterized the development of Alzheimer's Disease (AD). Despite a large number of studies dedicated to AD, key questions about the lifespan ...
Hett, Kilian; Ta, Vinh-Thong; Oguz, Ipek; Manjón Herrera, José Vicente; Coupé, Pierrick; Alzheimers Disease Neuroimaging Initiative(Elsevier, 2021-01)
[EN] The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer¿s disease (AD) is clinically relevant, and may above all have a significant impact on accelerating the development of new ...
[EN] Numerous studies have proposed biomarkers based on magnetic resonance imaging (MRI) to detect and predict the risk of evolution toward Alzheimer's disease (AD). Most of these methods have focused on the hippocampus, ...
Vendrell, Alexandre; Martínez Pastor, María Mar; González-Novo, Alberto; Pascual-Ahuir Giner, María Desamparados; Sinclair, David A.; Proft, Markus; Posas, Francesc(EMBO Press, 2011)
[EN] Exposure of yeast to high osmolarity induces a transient activation
of the Hog1 stress-activated protein kinase (SAPK), which
is required for cell survival under these conditions. However,
sustained activation of ...
[EN] Previous literature about the structural characterization of the human cerebellum is
related to the context of a specific pathology or focused in a restricted age range. In
fact, studies about the cerebellum maturation ...
[EN] There is no consensus in literature about lifespan brain maturation and senescence, mainly because previous lifespan studies have been performed on restricted age periods and/or with a limited number of scans, making ...