Melnyk, Tetiana(Universitat Politècnica de València, 2025-03-07)
[ES] Los tumores malignos del cerebro y del sistema nervioso central representan el 21% de los tumores en niños y son la segunda causa principal de muerte por cáncer pediátrico después de la leucemia. Los gliomas de alto ...
[EN] Following virtual screening and structure-based ligand optimization, researchers have developed opabactin (OP), an abscisic acid (ABA)-receptor agonist with tenfold greater in vivo activity than ABA. This new ligand ...
Radioisotope holmium is a candidate to be used in cancer treatment and diagnosis. There are different holmium salts and they present distinct solubility and consequently different biodistribution profiles. In this work, ...
[EN] The aim of this study was to determine whether the prophylactic use of antibiotics in intravaginal sponges used for estrus synchronization in goats may result in the presence of inhibitors in milk and, therefore, of ...
Cuquerella Alabort, Maria Consuelo; Lhiaubet, Virginie Lyria; Miranda Alonso, Miguel Ángel; Bosca Mayans, Francisco(The Royal Society of Chemistry, 2017)
[EN] The crucial role of photosensitizer@DNA complexation in the formation of cyclobutane pyrimidine dimers (CPDs) has been demonstrated using femtosecond and nanosecond transient absorption and emission measurements in ...
Nuin Plá, Neus Edurne; Jiménez Molero, María Consuelo; Sastre Navarro, German Ignacio; Andreu Ros, María Inmaculada; Miranda Alonso, Miguel Ángel(American Chemical Society, 2013-05-16)
A new direct and noninvasive methodology based on transient absorption spectroscopy has been developed to probe the feasibility of drug-drug interactions within a common protein binding site. The simultaneous presence of ...
Bosca Mayans, Francisco; Sastre Navarro, German Ignacio; Andreu, José María; Jornet, David; Tormos Faus, Rosa Esperanza; Miranda Alonso, Miguel Ángel(Royal Society of Chemistry, 2015)
[EN] Colchicine (COL) is a bioactive molecule with antitumor properties. When COL binds to tubulin (TU), it inhibits microtubule assembly dynamics. We have investigated COL-TU interactions using laser flash photolysis (LFP) ...
Gustavsson, Thomas; Markovitsi, Dimitra; Vayá Pérez, Ignacio; Bonancía Roca, Paula; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(Society of Photo-optical Instrumentation Engineers (SPIE), 2014)
[EN] We report here on a recent time-resolved fluorescence study [1] of the interaction between flurbiprofen (FBP), a chiral non-steroidal anti-inflammatory drug, and human serum albumin (HSA), the main transport protein ...
[EN] The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the seventh known human coronavirus, and it was identified in Wuhan, Hubei province, China, in 2020. It caused the highly contagious disease called ...
Moura, Ana; Barreiros, João; Cordeiro, M. Natália(Editorial Universitat Politècnica de València, 2020-04-30)
[EN] Higher Education Student burnout is an increasingly educational and social concern. The problem is complex and multilayered, demanding new approaches in predicting hazardous situations that can lead to the demise of ...
Frictional behaviour of ZE10 and AZ80 magnesium alloys was investigated using a sheet metal forming simulator (SMFS) with a steel pin as counterpart on dry sliding conditions. Friction coefficients were measured within a ...
[EN] There are unique and varied examples of dry stone constructions in the Mediterranean region, whose interest,
in Puglia (Italy) and attested in recent decades, has determined a speculative attitude that has made ...
Ochiai, Chiho; Wang, Jingying(Editorial Universitat Politècnica de València, 2022-09-13)
[EN] Shishigaki (wild boar defense walls), as a part of cultural landscapes in Japan, currently faces serious deterioration. The research aims to identify the characteristics of Shishigaki walls in eight villages located ...
[EN] This work presents the initial results of the dry-sliding wear behavior of 3 mol% yttria-stabilized zirconia reinforced with 5 vol% alumina-niobium carbide (3Y-TZP/5 vol% Al2O3-NbC) nanocomposites sintered by conventional ...
Whaley, Michael; Poandl, F.(Editorial Universitat Politècnica de València, 2018-09-07)
[EN] The evaporation of water is a major energy consumer around the world where the evaporation of water from agricultural products, natural resources, processed foods and feeds, and petrochemical products is required for ...
Ahmad-Qasem Mateo, Margarita Hussam; Ahmad-Qasem, B.; Barrajon-Catalan, Enrique; Micol-Molina, Vicente; Carcel Carrión, Juan Andrés; García Pérez, José Vicente(Elsevier, 2016)
[EN] There is an increasing demand for natural antioxidants in the food, cosmetics and pharmaceutical industries which has led to the search not only for natural extracts but also for strategies with which to increase ...
[EN] In order to conserve cuminum cyminum L. during long storage periods, the drying kinetics of this seed undergoing microwave-assisted fluidized bed dryer at various microwave output power (300, 600 and 900w), air velocity ...
Satimehin, A.; Oluwamukomi, M.; Enujiugha, V. N.; Bello, M.(Editorial Universitat Politècnica de València, 2018-09-07)
[EN] This study was conducted to determine the drying characteristics of oyster mushroom (Pleurotus ostreatus) at 50, 60 and 70 °C. Pleurotus ostreatus were cleaned and dried in a laboratory cabinet dryer. The drying data ...