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"Snorkelling" vs. "diving" in mixed micelles probed by means of a molecular bathymeter

Rodríguez Muñiz, Gemma María; Gomez Mendoza, Miguel; Nuin Pla, Neus Edurne; Andreu Ros, María Inmaculada; Marín García, Mª Luisa; Miranda Alonso, Miguel Ángel (The Royal Society of Chemistry, 2017)

[EN] A photoactive bathymeter based on a carboxylic acid moiety covalently linked to a signalling methoxynaphthalene (MNP) fluorophore has been designed to prove the concept of "snorkelling" vs. "diving" in mixed micelles ...
3D Culture o Multiple Myeloma Cell Line Using Microgel Environments

Marin Paya, Juan Carlos (Universitat Politècnica de València, 2021-06-03)

[ES] El mieloma múltiple es una neoplasia hematológica caracterizada por una expansión descontrolada de células plasmáticas monoclonales (mPCs) en medula ósea que producen, en la mayoría de los casos, un componente monoclonal ...
A Ciliary Motility Index for Activity Measurement in Cell Cultures With Respiratory Syncytial Virus

Parrilla Bernabé, Eduardo; Armengot, Miguel; Mata, Manuel; Carda, Carmen; Cortijo, Julio; Moratal, David; Ginestar Peiro, Damián; Hueso, José L.; Riera Guasp, Jaime (SAGE Publishing, 2019-03-01)

[EN] Background: The respiratory epithelium is frequently infected by the respiratory syncytial virus, resulting in inflammation, a reduction in cilia activity and an increase in the production of mucus. Methods: In this ...
A comparative study on Poly(ε-caprolactone) film degradation at extreme pH values

Sailema-Palate, G. Patricia; Vidaurre Garayo, Ana Jesús; Campillo Fernández, Alberto José; Castilla Cortázar, María Isabel Cecilia (Elsevier, 2016-08)

The present paper studies the effect of pH on hydrolytic degradation of Poly(ε-aprolactone) (PCL) Degradation of the films was performed at 37 C in 2.5 M NaOH solution (pH 13) and 2.5 M HCl solution (pH 1). Weight ...
A comparison of Covid-19 early detection between convolutional neural networks and radiologists

Albiol Colomer, Alberto; Albiol, Francisco; Paredes Palacios, Roberto; Plasencia-Martínez, Juana María; Blanco Barrio, Ana; García Santos, José M.; Tortajada, Salvador; González Montaño, Victoria M.; Rodríguez Godoy, Clara E.; Fernández Gómez, Saray; Oliver-Garcia, Elena; de la Iglesia Vayá, María; Márquez Pérez, Francisca L.; Rayo Madrid, Juan I. (SpringerOpen, 2022-07-28)

[EN] Background The role of chest radiography in COVID-19 disease has changed since the beginning of the pandemic from a diagnostic tool when microbiological resources were scarce to a different one focused on detecting ...
A Drosophila model of GDAP1 function reveals the involvement of insulin signalling in the mitochondria-dependent neuromuscular degeneration

Lopez del Amo, V; Palomino-Schätzlein, Martina; Seco-Cervera, Marta; Garcia-Gimenez, José Luis; Pallardó-Calatayud, Federico V.; Pineda-Lucena, Antonio; Galindo-Orozco, Máximo Ibo (Elsevier, 2017)

[EN] Charcot-Marie-Tooth disease is a rare peripheral neuropathy for which there is no specific treatment. Some forms of Charcot-Marie-Tooth are due to mutations in the GDAP1 gene. A striking feature of mutations in GDAP1 ...
A fixed point theorem for preordered complete fuzzy quasi-metric spaces and an application

Castro Company, Francisco; Romaguera Bonilla, Salvador; Tirado Peláez, Pedro (SpringerOpen, 2014-03)

We obtain a fixed point theorem for a type of generalized contractions on preordered complete fuzzy quasi-metric spaces which is applied to deduce, among other results, a procedure to show in a direct and easy fashion the ...
A fluorogenic capped mesoporous aptasensor for gluten detection

Pla, Luis; Martínez-Bisbal, M.Carmen; Aznar, Elena; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Santiago Felipe, Sara (Elsevier, 2021-02-22)

[EN] Celiac disease is a complex and autoimmune disorder caused by the ingestion of gluten affecting almost 1% of global population. Nowadays an effective treatment does not exist, and the only way to manage the disease ...
A Gene Signature Combining the Tissue Expression of Three Angiogenic Factors is a Prognostic Marker in Early-stage Non-small Cell Lung Cancer

Sanmartín, Elena; Sirera Pérez, Rafael; Usó, Marta; Blasco, Ana; Gallach, Sandra; Figueroa, Santiago; Martínez, Nieves; Hernando, Cristina; Honguero, Antonio; Martorell, Miguel; Guijarro, Ricardo; Rosell, Rafael; Jantus-Lewintre, Eloisa; Camps, Carlos (Springer Verlag (Germany), 2014-02)

[EN] Background. Angiogenesis and lymphangiogenesis are key mechanisms for tumor growth and dissemination. They are mainly regulated by the vascular endothelial growth factor (VEGF) family of ligands and receptors. The aim ...
A generic and extensible automatic classification framework applied to brain tumour diagnosis in HealthAgents

Sáez Silvestre, Carlos; García Gómez, Juan Miguel; Vicente Robledo, Javier; Tortajada Velert, Salvador; Luts, Jan; Dupplaw, David; Van Huffel, Sabine; Robles Viejo, Montserrat (Cambridge University Press (CUP), 2011-09)

[EN] New biomedical technologies enable the diagnosis of brain tumours by using non-invasive methods. HealthAgents is a European Union-funded research project that aims to build an agent-based distributed decision support ...
A membrane computing simulator of trans-hierarchical antibiotic resistance evolution dynamics in nested ecological compartments (ARES)

Campos Frances, Marcelino; Llorens, Carlos; Sempere Luna, José María; Futami, Ricardo; Rodríguez, Irene; Carrasco, Purificación; Capilla, Rafael; Latorre, Amparo; Coque, Teresa M.; Moya, Andrés; Baquero, Fernando (BioMed Central, 2015)

In this article, we introduce ARES (Antibiotic Resistance Evolution Simulator) a software device that simulates P-system model scenarios with five types of nested computing membranes oriented to emulate a hierarchy of ...
A new 8-oxo-7,8-2 ' deoxyguanosine nanoporous anodic alumina aptasensor for colorectal cancer diagnosis in blood and urine

Pla, Luis; Sancenón Galarza, Félix; Martínez-Bisbal, M.Carmen; Bañuls, Celia; Estañ, Nuria; Botello-Marabotto, Marina Dolores; Aznar, Elena; Sáez, Guillermo; Santiago-Felipe, Sara; Martínez-Máñez, Ramón (The Royal Society of Chemistry, 2021-05-14)

[EN] Many important human diseases, and especially cancer, have been related to the overproduction of 8-oxo-7,8-dihydro-2 '-deoxyguanosine (8-oxo-dG). This molecule is a product of oxidative stress processes over nucleophilic ...
A new single-instrument technique for parenchyma division and hemostasis in liver resection: a clinical feasibility study

Burdío, Fernando; Grande, Luis; Berjano, Enrique; Martinez-Serrano, Maria; Poves, Ignasi; Burdío, José M.; Navarro, Ana; Güemes, Antonio (Elsevier, 2010-12)

[EN] The objective of this study was to evaluate the clinical feasibility of a new technique for liver resection based on a radiofrequency-assisted (485 kHz) device that has shown high performance in the animal setting ...
A new waterborne chitosan-based polyurethane hydrogel as a vehicle to transplant bone marrow mesenchymal cells improved wound healing of ulcers in a diabetic rat model

Viezzer, Christian; Mazzuca, Rafael; Machado, Denise Cantarelli; Forte, María Magdalena de Camargo; Gómez Ribelles, José Luís (Elsevier, 2020-03-01)

[EN] Foot ulcers, a common complication of diabetes, can cause physical incapacity and are derived from several factors, including poor wound healing. New therapeutic strategies are needed to minimize this complication for ...
A Nextflow pipeline for T-cell receptor repertoire reconstruction and analysis from RNA sequencing data

Rubio, Teresa; Chernigovskaya, Maria; Marquez, Susanna; Marti, Cristina; Izquierdo-Altarejos, Paula; Urios, Amparo; Montoliu, Carmina; Felipo, Vicente; Conesa, Ana; Greiff, Victor; Tarazona, Sonia (Elsevier B.V., 2022-03-12)

[EN] T-cell receptor (TCR) analysis is relevant for the study of immune system diseases. The expression of TCRs is usually measured with targeted sequencing approaches where TCR genes are selectively amplified. However, ...
A Novel Clinical and Stress Cardiac Magnetic Resonance (C-CMR-10) Score to Predict Long-Term All-Cause Mortality in Patients with Known or Suspected Chronic Coronary Syndrome

Marcos-Garces, Victor; Gavara-Doñate, Josep; Monmeneu-Menadas, Jose Vicente; Lopez-Lereu, Maria P.; Pérez, Nerea; Rios-Navarro, César; De Dios, Elena; Moratal, David; Miñana, Gema; Núñez, Julio; Chorro Gasco, Francisco J.; Bodi, V. (MDPI AG, 2020-06)

[EN] Vasodilator stress cardiac magnetic resonance (stressCMR) has shown robust diagnostic and prognostic value in patients with known or suspected chronic coronary syndrome (CCS). However, it is unknown whether integration ...
A novel delins mutation in the alpha-TTP gene in a family segregating ataxia with isolated vitamin E deficiency

Fernández-Burriel, Miguel; Martínez-Rubio, Dolores; Lupo,Vincenzo; Pérez-Colosía, Víctor; Piñán López, Esther; Palau, Francesc; Espinós-Armero, Carmen Ángeles (Nature Publishing Group, 2008-09)

[EN] Ataxia with isolated vitamin E deficiency is a rare autosomal recessive neurodegenerative disease due to mutations in the a-tocopherol transfer protein gene. In ataxia with isolated vitamin E deficiency, the biochemical ...
A patient-specific FE-based methodology to simulate prosthesis insertion during an augmentation mammoplasty

Lapuebla-Ferri, Andrés; Perez del Palomar, Amaya; Herrero, Javier; Jimenez Mocholi, Antonio José (Elsevier, 2011)

[EN] Breast augmentation surgery is a widespread practice for aesthetic purposes. Current techniques, however, are not able to reliably predict the desired final aspect of the breast after the intervention, whose success ...
A possible use of melatonin in the dental field: Protein adsorption and in vitro cell response on coated titanium

Cerqueira, Andreia; Romero-Gavilán, Francisco; Araujo-Gomes, Nuno; García-Arnáez, Iñaki; Martínez-Ramos, Cristina; Ozturan, Seda; Azkargorta, Mikel; Elortza, Félix; Gurruchaga, Mariló; Suay, Julio; Goñi, Isabel (Elsevier BV, 2020-11)

[EN] Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in bone regeneration and inflammation. Its application as a coating for dental implants can condition the local ...
A relevant IgE-reactive 28 kDa protein identified from Salsola kali pollen extract by proteomics is a natural degradation product of an integral 47 kDa polygalaturonase

Mas-García, Salvador; Oeo-Santos, Carmen; Cuesta-Herranz, Javier; Díaz-Perales, Araceli; Colás, Carlos; Fernández, Javier; Barber, Domingo; Rodríguez, Rosalía; de los Ríos, Vivian; Barderas, Rodrigo; Villalba, Mayte (Elsevier, 2017-08)

[EN] A highly prevalent IgE-binding protein band of 28 kDa is observed when Salsola kali pollen extract is incubated with individual sera from Amaranthaceae pollen sensitized patients. By an immunoproteomic analysis of S. ...