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Browsing by Subject "Lung cancer"

Now showing items 1-11 of 11

2D and 3D texture analysis to differentiate brain metastases on MR images: proceed with caution

Beresova, Monika; Larroza, Andrés; Arana, Estanislao; Varga, Jozsef; Balkay, Laszlo; Moratal, David (Springer-Verlag, 2018-04)

[EN] To find structural differences between brain metastases of lung and breast cancer, computing their heterogeneity parameters by means of both 2D and 3D texture analysis (TA). Patients with 58 brain metastases from ...
Análisis de herramientas para acelerar la transferencia de conocimiento cientifico

Manukyan Melkumyan, Erika (Universitat Politècnica de València, 2018-02-14)

Lately, there has been an exponential advance in the biomedical field. Nonetheless these discoveries do not really mean direct mean direct benefits for the patients, or take a long time to arrive to the population. The ...
Caracterización de la Interacción entre Célula Madre Tumoral y Microambiente Inmune en el Cáncer de Pulmón no Microcítico

Torres Martínez, Susana (Universitat Politècnica de València, 2017-08-31)

Non-small cell lung cancer (NSCLC) is one of the solid tumors with the highest mortality in the world. The acquisition of treatment¿s resistances, together with the lack of treatment¿s effectiveness on Cancer Stem Cells ...
Caracterización in vitro de un nuevo fármaco bioconjugado para el tratamiento del cáncer de pulmón

Velasco Vila, Sergi (Universitat Politècnica de València, 2020-10-06)

[ES] El cáncer es una enfermedad heterogénea que causa más de la mitad de las muertes en países desarrollados. En particular, el cáncer de pulmón es el que tiene mayor incidencia y mortalidad a nivel global. El adenocarcinoma ...
Fifth Educational Symposium of the Spanish Lung Cancer Group: report on the Molecular Biology Workshop

Bover, Isabel; Rolfo, Christian; Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Camps, Carlos; Chaib, Imane; Ramirez-Serrano, Jose L.; Benlloch, Susana; Molina-Vila, Miguel Angel; Simonetti, Sara; Costa, Carlota; Gimenez-Capitan, Ana; Mendez, Pedro; Taron, Miguel; Rosell, Rafael (Elsevier, 2011-12)

The majority of non-small-cell lung cancer (NSCLC) patients present with locally advanced (35%) or metastatic disease (40%); in this setting, it is of the utmost importance to balance efficacy with toxicity. However, with ...
Fitocannabinoides como posibles agentes moduladores de la transición epitelio-mesénquima en cáncer de pulmón

Urbina Jara, Laura Keren (Universitat Politècnica de València, 2020-06-22)

[ES] El cáncer de pulmón es una de las principales enfermedades causantes de muerte actualmente en el mundo, por lo cual su estudio es imperativo. Los datos de GOBLOCAN 2012 muestran un índice de mortalidad en España por ...
Impacto de la tecnología de secuenciación masiva en el cáncer de pulmón no microcítico

Tébar Martínez, Roberto (Universitat Politècnica de València, 2016-09-05)

[ES] Introducción En el cáncer de pulmón no microcítico (CPNM) es necesaria la identificación de biomarcadores que permitan la caracterización molecular del tumor y, con ello, adecuar el manejo de los pacientes1. En este ...
Investigation of Complement Activation Product C4d as a Diagnostic and Prognostic Biomarker for Lung Cancer

Jantus Lewintre, Eloisa (Oxford University Press (OUP), 2013)

[EN] Background There is a medical need for diagnostic biomarkers in lung cancer. We evaluated the diagnostic performance of complement activation fragments. Methods We assessed complement activation in four bronchial ...
miRNA detection methods and clinical implications in lung cancer

Usó, Marta; Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Bremnes, Roy M.; Camps, Carlos (Future Medicine, 2014)

[EN] Lung cancer is the leading cause of cancer death worldwide. Therefore, advances in the diagnosis and treatment of the disease are urgently needed. miRNAs are a family of small, noncoding RNAs that regulate gene ...
The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer

Bremnes, Roy M.; Donnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid; Andersen, Sigve; Sirera Pérez, Rafael; Camps, Carlos; Marinez, Inigo; Busund, Lill-Tove (Lippincott, Williams & Wilkins, 2011-01)

[EN] Maintenance of both normal epithelial tissues and their malignant counterparts is supported by the host tissue stroma. The tumor stroma mainly consists of the basement membrane, fibroblasts, extracellular matrix, ...
The role of tumor-infiltrating immune cells and chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer

Bremnes, Roy M.; Al-Shibli, Khalid; Donnem, Tom; Sirera Pérez, Rafael; Al-Saad, Samer; Andersen, Sigve; Stenvold, Helge; Camps, Carlos; Busund, Lill-Tove (Lippincott, Williams & Wilkins, 2011-04)

[EN] In addition to malignant neoplastic cells, cancer tissues also include immune cells, fibroblasts, and endothelial cells, including an abundant collection of growth factors, proangiogenic mediators, cytokines, chemokines, ...