[EN] To find structural differences between brain metastases of lung and breast cancer, computing their heterogeneity parameters by means of both 2D and 3D texture analysis (TA).
Patients with 58 brain metastases from ...
Manukyan Melkumyan, Erika(Universitat Politècnica de València, 2018-02-14)
Lately, there has been an exponential advance in the biomedical field. Nonetheless these discoveries do not really mean direct mean direct benefits for the patients, or take a long time to arrive to the population. The ...
Torres Martínez, Susana(Universitat Politècnica de València, 2017-08-31)
Non-small cell lung cancer (NSCLC) is one of the solid tumors with the highest mortality in the world. The acquisition of treatment¿s resistances, together with the lack of treatment¿s effectiveness on Cancer Stem Cells ...
The majority of non-small-cell lung cancer (NSCLC) patients present with locally advanced (35%) or metastatic disease (40%); in this setting, it is of the utmost importance to balance efficacy with toxicity. However, with ...
Urbina Jara, Laura Keren(Universitat Politècnica de València, 2020-06-22)
[ES] El cáncer de pulmón es una de las principales enfermedades causantes de muerte actualmente en
el mundo, por lo cual su estudio es imperativo. Los datos de GOBLOCAN 2012 muestran un índice
de mortalidad en España por ...
González-Gualda, Estela; Pàez-Rives, Marta; Lozano-Torres, Beatriz; Macias, David; Wilson III, Joseph R.; González-López, Cristina; Ou, Hui-Ling; MIrón-Barroso, Sofía; Zhang, Zhenguang; Lérida-Viso, Araceli; Blandez, Juan F.; Bernardos Bau, Andrea; Sancenón Galarza, Félix; Rovira, Miguel; Fruk, Ljiljana; Martins, Carla P.; Serrano, Manuel; Doherty, Gary J.; Martínez-Máñez, Ramón; Muñoz-Espín, Daniel(Blackwell Publishing, 2020-04)
[EN] Pharmacologically active compounds with preferential cytotoxic activity for senescent cells, known as senolytics, can ameliorate or even revert pathological manifestations of senescence in numerous preclinical mouse ...
Tébar Martínez, Roberto(Universitat Politècnica de València, 2016-09-05)
[ES] Introducción
En el cáncer de pulmón no microcítico (CPNM) es necesaria la identificación de biomarcadores que permitan la caracterización molecular del tumor y, con ello, adecuar el manejo de los pacientes1. En este ...
Jantus Lewintre, Eloisa(Oxford University Press (OUP), 2013)
[EN] Background There is a medical need for diagnostic biomarkers in lung cancer. We evaluated the diagnostic performance of complement activation fragments.
Methods We assessed complement activation in four bronchial ...
Usó, Marta; Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Bremnes, Roy M.; Camps, Carlos(Future Medicine, 2014)
[EN] Lung cancer is the leading cause of cancer death worldwide. Therefore, advances in the diagnosis and treatment of the disease are urgently needed. miRNAs are a family of small, noncoding RNAs that regulate gene ...
Bremnes, Roy M.; Donnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid; Andersen, Sigve; Sirera Pérez, Rafael; Camps, Carlos; Marinez, Inigo; Busund, Lill-Tove(Lippincott, Williams & Wilkins, 2011-01)
[EN] Maintenance of both normal epithelial tissues and their malignant counterparts is supported by the host tissue stroma. The tumor stroma mainly consists of the basement membrane, fibroblasts, extracellular matrix, ...
Bremnes, Roy M.; Al-Shibli, Khalid; Donnem, Tom; Sirera Pérez, Rafael; Al-Saad, Samer; Andersen, Sigve; Stenvold, Helge; Camps, Carlos; Busund, Lill-Tove(Lippincott, Williams & Wilkins, 2011-04)
[EN] In addition to malignant neoplastic cells, cancer tissues also include immune cells, fibroblasts, and endothelial cells, including an abundant collection of growth factors, proangiogenic mediators, cytokines, chemokines, ...