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Browsing by Subject "Molecular gates"

Now showing items 1-20 of 20

A photoactivated molecular gate

Agostini, Alessandro (Universitat Politècnica de València, 2016-02-02)

A novel capped silica nanoscopic mesoporous hybrid material for photo-driven cargo release applications has been designed and prepared. The capped system, which shows a zero release, contains a photo-cleavable bulky ...
Biocompatible Phenylboronic-Acid-Capped ZnS Nanocrystals Designed As Caps in Mesoporous Silica Hybrid Materials for on-Demand pH-Triggered Release In Cancer Cells

Salinas Soler, Yolanda; Hoerhager, Carolin; García-Fernández, Alba; Resmini, Marina; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Brueggemann, Oliver (American Chemical Society, 2018)

[EN] Biocompatible ZnS-based nanocrystals capped with 4-mercaptophenylboronic acid (ZnS@B) have been size-designed as excellent pH responsive gatekeepers on mesoporous silica nanoparticles (MSNs), which encapsulate fluorophore ...
Desarrollo de scaffolds inteligentes para la prevención y tratamiento de la infección ósea

Polo Aguado, Lorena (Universitat Politècnica de València, 2016-11-02)

[EN] Bone infection is one of the most common problems that usually appear after a prosthesis surgery. In this work, we propose the development and characterisation of a mesoporous material, which can be 3D-printed in the ...
Desarrollo y síntesis de materiales híbridos para la liberación controlada de moléculas antimicrobianas de origen natural

Pemartín González-Adalid, María Teresa (Universitat Politècnica de València, 2019-09-02)

[ES] El desarrollo de dispositivos de liberación controlada utilizando materiales híbridos mesoporosos y su aplicación en campos como la agricultura, la alimentación, la nanomedicina o la biomedicina entre otros, ha tenido ...
Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups

Agostini, Alessandro; Mondragón Martínez, Laura; Pascual Vidal, Lluís; Aznar Gimeno, Elena; Coll Merino, Mª Carmen; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Soto Camino, Juan; Marcos Martínez, María Dolores; Amoros del Toro, Pedro; Costero, Ana M.; Parra, Margarita; Gil, Salvador (American Chemical Society, 2012-09-21)

[EN] An ethylene glycol-capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two-step procedure. ...
Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups

Pascual Vidal, Lluís (Universitat Politècnica de València, 2016-02-01)

An ethylene glycol capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two step procedure. ...
Design of oligonucleotide-capped mesoporous silica nanoparticles for the detection of miRNA-145 by duplex and triplex formation

Ribes, Àngela; Santiago Felipe, Sara; Aviñó, Anna; Candela-Noguera, Vicente; Eritja, Ramón; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Aznar, Elena (Elsevier, 2018-12)

[EN] The development of new strategies to detect microRNAs (miRNAS) has become an important challenge in thebiomedical ¿eld. We report herein the use of oligonucleotide-gated silica nanoparticles for the detection ofmiRNA-145. ...
Enzyme-controlled sensing-actuating nanomachine based on Janus Au-mesoporous silica nanoparticles

Villalonga, Reynaldo; Díez, Paula; Sánchez, Alfredo; Aznar, Elena; Martínez-Máñez, Ramón; Pingarrón, J.M. (John Wiley & Sons, 2013-06)

[EN] Novel Janus nanoparticles with Au and mesoporous silica faces on opposite sides were prepared using a Pickering emulsion template with paraffin wax as the oil phase. These anisotropic colloids were employed as integrated ...
Enzyme-functionalized hybrid mesoporous nanodevices for sensing, controlled release and molecular communication

Llopis Lorente, Antoni (Universitat Politècnica de València, 2019-03-04)

[ES] La presente tesis doctoral titulada "Nanodispositivos mesoporosos híbridos funcionalizados con enzimas para detección, liberación controlada y comunicación molecular" se centra en el diseño, preparación, caracterización ...
Enzyme-mediated controlled release systems by anchoring peptide sequences on mesoporous silica supports

Coll Merino, Mª Carmen; Mondragón Martínez, Laura; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Soto Camino, Juan; Amoros del Toro, Pedro Jose; Pérez Payá, Enrique (Wiley-VCH Verlag, 2011-02-01)

Gated community: Peptides anchored to the surface of silica mesoporous supports by a valid procedure act as gatekeepers. In this way, "zero release" supports that selectively deliver the cargo in the presence of a suitable ...
Evaluación de un sistema de enmascaramiento de olor de muestras de ajo, mediante un sistema de nariz electrónica

Ordoñez Araque, Roberto Hugo (Universitat Politècnica de València, 2015-11-12)

[ES] La tendencia actual de la industria agroalimentaria se enfoca en el desarrollo de alimentos funcionales y naturales para el consumo diario. El ajo, por ejemplo, presenta una actividad antioxidante y antimicrobiana ...
Finely tuned temperature-controlled cargo release using paraffin-capped mesoporous silica nanoparticles

Aznar Gimeno, Elena; Mondragón Martínez, Laura; Ros-Lis, José Vicente; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Martínez Mañez, Ramón; Soto Camino, Juan; Pérez Payá, Enrique; AMOROS DEL TORO, PEDRO (Wiley-VCH Verlag, 2011-09-27)

Trapped: Mesoporous silica nanoparticles were loaded with a fluorescent guest and functionalized with octadecyltrimethoxysilane. The alkyl chains interact with paraffins, which build a hydrophobic layer around the particle ...
Gated hybrid delivery systems: En route to sensory materials with inherent signal amplification

Hecht, Mandy; Climent Terol, Estela; Biyikal, Mustafa; Sancenón Galarza, Félix; Martínez Mañez, Ramón; Rurack, Knut (Elsevier, 2013-09)

Hybrid nanoparticles with a large specific surface area are a particularly exciting vehicle for delivery applications. Such highly porous or container-like structures, usually prepared from silica and frequently from gold, ...
Implementation of oligonucleotide-gated supports for the electrochemical detection of Ochratoxin A

Muthamizh, S.; Ribes, Àngela; Anusuyajanakiraman, M.; Narayanan, V.; Soto Camino, Juan; Martínez-Máñez, Ramón; Aznar, Elena (Taylor & Francis, 2017)

[EN] We report herein the design a hybrid material for the recognition of Ochratoxin A (OTA) by using an aptamer gated-material able to release electroactive species, which can be measured using differential pulse voltammetry. ...
Materiales de sílice mesoporosa bioinspirados para la liberación controlada de moléculas naturales bioactivas

García Casado, Esther (Universitat Politècnica de València, 2020-07-14)

[ES] La actividad antimicrobiana de los componentes de los aceites esenciales (CAEs) es bien conocida. Sin embargo, su alta volatilidad y su potente aroma limitan su aplicación en la formulación de una amplia gama de ...
Mesoporous Silica-Based Supports for the Controlled and Targeted Release of Bioactive Molecules in the Gastrointestinal Tract

Pérez-Esteve, Édgar; Ruiz Rico, María; Martínez-Máñez, Ramón; Barat Baviera, José Manuel (Wiley, 2015-11)

Mesoporous silica particles (MSPs) have attracted increasing interest as supports in the design of controlled delivery materials. Besides their excellent properties as loading supports (that is, large surface area and pore ...
New supramolecular nanoscopic hybrid gate-like ensembles with dual –pH and cation-driven- aperture control

Sapiña Escrivá, María (Universitat Politècnica de València, 2016-02-02)

• Synthesize and characterize the nanostructured material that is going to act as the inorganic support of the hybrid gate system. In or case an MCM-41 type material in two different morphologies, microparticles and ...
Nutritional effects of folic acid controlled release from mesoporous materials

Barat Baviera, José Manuel; Pérez-Esteve, Édgar; Bernardos Bau, Andrea; Martínez-Máñez, Ramón (Elsevier, 2011)

[EN] Folic acid deficiency causes serious disorders in humans and supplementation has numerous health benefits. However, there is initial evidence that suggest a negative impact of an increased exposure to folic with respect ...
Smart drug delivery systems designed to improve Inflammatory Bowel Disease therapy

Hernández Teruel, Adrián (Universitat Politècnica de València, 2019-10-21)

[ES] La presente tesis doctoral titulada "Sistemas de liberacio'n controlada de fa'rmacos diseñados para mejorar el tratamiento de Enfermedad Inflamatoria Intestinal" se centra en el diseño, preparación, caracterización y ...
Triplex hybridization-based nanosystem for the rapid screening of pneumocystis pneumonia in clinical samples

Pla, Luis; Aviñó, Anna; Eritja, Ramón; Ruiz-Gaitán, Alba; Pemán, Javier; Friaza, Vicente; Calderón, Enrique J.; Aznar, Elena; Martínez-Máñez, Ramón; Santiago Felipe, Sara (MDPI, 2020-12)

[EN] Pneumocystis pneumonia (PcP) is a disease produced by the opportunistic infection of the fungus Pneumocystis jirovecii. As delayed or unsuitable treatments increase the risk of mortality, the development of rapid and ...