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Browsing by Subject "Breast cancer"

Now showing items 1-20 of 23

A Gene Signature Combining the Tissue Expression of Three Angiogenic Factors is a Prognostic Marker in Early-stage Non-small Cell Lung Cancer

Sanmartín, Elena; Sirera Pérez, Rafael; Usó, Marta; Blasco, Ana; Gallach, Sandra; Figueroa, Santiago; Martínez, Nieves; Hernando, Cristina; Honguero, Antonio; Martorell, Miguel; Guijarro, Ricardo; Rosell, Rafael; Jantus-Lewintre, Eloisa; Camps, Carlos (Springer Verlag (Germany), 2014-02)

[EN] Background. Angiogenesis and lymphangiogenesis are key mechanisms for tumor growth and dissemination. They are mainly regulated by the vascular endothelial growth factor (VEGF) family of ligands and receptors. The aim ...
A molecular framework for understanding dcis

Gutiérrez Ángel, Sara (2015-05-20)

[EN] Ductal carcinoma In situ (DCIS) is known as the stage zero of breast cancer. It develops within the mammary ducts and it can become invasive, arising into Invasive Ductal Carcinoma (IDC). The goal of the present ...
A Systematic Approach for Using DICOM Structured Reports in Clinical Processes: Focus on Breast Cancer

Medina, Rosana; Torres Serrano, Erik; Segrelles Quilis, José Damián; Blanquer Espert, Ignacio; Martí Bonmatí, Luis; Almenar-Cubells, Daniel (Springer Verlag (Germany), 2015-04)

This paper describes a methodology for redesigning the clinical processes to manage diagnosis, follow-up, and response to treatment episodes of breast cancer. This methodology includes three fundamental elements: (1) ...
Acute stress trajectories 1 year after a breast cancer diagnosis

Perez, Sandra; Conchado Peiró, Andrea; Andreu, Yolanda; Galdon, Maria Jose; Cardena, Etzel; Ibanez, Elena; Dura, Estrella (Springer Verlag (Germany), 2016-04)

Purpose The purpose of this study was to evaluate the longitudinal trajectories of acute stress reactions over the course of diagnosis, treatment, and follow-up assessments in a group of non-metastatic breast cancer patients ...
Análisis de texturas de imágenes PET/TC para la caracterización, cuantificación y ayuda en el diagnóstico del cáncer de mama.

Mancebo González, María (2019-10-07)

[ES] Una de las características más comunes que presentan los tumores cancerígenos es la falta de oxígeno o hipoxia, la cual contribuye de manera directa a su proliferación y metástasis, además de disminuir su sensibilidad ...
Biotecnología para la Medicina de Precisión: Identificación de Variaciones Genómicas para el Diagnóstico de Cáncer de Mama.

Escalera Balsera, Alba (2018-09-18)

[ES] El manejo eficiente de datos es un problema esencial para garantizar un diagnóstico correcto en el ámbito de una Medicina de Precisión (MP) efectiva y adecuada. Ciencia de Datos y Biotecnología deben unir sus fuerzas ...
Breast cancer mortality in Spain: Has it really declined?

Álvaro Meca, A.; Debón Aucejo, Ana María; Gil Prieto, R.; Gil de Miguel, Á. (WB Saunders, 2012-10)

Objectives: In recent years, the incidence of breast cancer has increased in Spain but mortality has decreased, particularly since 1992. Despite the general decrease in mortality, the intensity of this disease differs ...
Caracterización y efecto de TRIM29 en líneas celulares de cáncer de mama triple negativo

Catalá Martínez, Francisco (2016-09-05)

[ES] La recaída en cáncer de mama es una de las mayores causas de morbilidad en pacientes que desarrollan la enfermedad y, de ellas, entre un 15-20% poseerán tumores de mama triple negativo. La mortalidad de pacientes con ...
Desarrollo de conjugados polímericos para el tratamiento del cáncer de mama.

Carrascosa Marzo, Rafael (2016-06-14)

[EN] The medical application of nanotechnology holds a tremendous potential in the bettering of human health, particularly in grave chronic pathologies such as cancer. Within cancer many defective processes have been ...
Desarrollo de una aplicación para el cálculo de biomarcadores basados en el tensor de difusión a partir de imágenes de MRI DTI de cáncer de mama mediante técnicas de análisis y modelado estadístico multivariante.

Robles Lozano, Guillermo (2019-10-28)

[ES] El objetivo principal de este trabajo es el desarrollo de una aplicación para el cálculo de biomarcadores y parámetros basados en el tensor de difusión mediante técnicas estadísticas multivariantes a partir de los ...
Design and first results of an innovative and dedicated for hanging breast imaging PET

González Martínez, Antonio Javier; S Aukema, T.; Barberá Ballester, Julio; Benlloch Baviera, Jose María; Correcher Salvador, Carlos; Orero Palomares, Abel; Soriano Asensi, Antonio; Vogel, W.; Vazquez Barreiros, Carlos; Vidal San Sebastián, Luis Fernando; Valdes Olmos, A.R. (Bentham Science Publishers, 2012-05-01)

In this work the design and preliminary clinical results obtained with an innovative and dedicated breast PET is presented. A geometrical study clearly pointed out the advantages of the prone position and the technique of ...
Desregulación de microARNs en el cáncer de mama triple negativo: papel en la resistencia a quimioterapia.

March Yagüe, Aina (2018-09-18)

[ES] El cáncer es una enfermedad que afecta a gran parte de la población, siendo el cáncer de mama el más frecuentemente diagnosticado en mujeres. Su incidencia está aumentando, siendo hoy en día la principal causa de ...
Estimación semiautomática de la densidad mamaria con DM-Scan

Martinez Gomez, Inmaculada; Casals el Busto, María; Antón Guirao, Joaquín; Ruiz Perales, Francisco; Llobet Azpitarte, Rafael (Elsevier, 2014)

[EN] Objective To evaluate the reproducibility of the calculation of breast density with DM-Scan software, which is based on the semiautomatic segmentation of fibroglandular tissue, and to compare it with the reproducibility ...
Estudio de inhibidores de la ruta PI3K/AKT/mTOR en líneas celulares de carcinoma de mama con sobre-expresión de HER2, resistentes a Trastuzumab

Espín Armas, Estefanía Alejandra (2015-05-11)

[EN] HER2-overexpressing breast cancer has an aggressive phenotype and poor prognosis. Trastuzumab, an anti-HER2 monoclonal antibody, has demonstrated therapeutic efficacy on this breast cancer subtype. Nonetheless, primary ...
Fifth Educational Symposium of the Spanish Lung Cancer Group: report on the Molecular Biology Workshop

Bover, Isabel; Rolfo, Christian; Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Camps, Carlos; Chaib, Imane; Ramirez-Serrano, Jose L.; Benlloch, Susana; Molina-Vila, Miguel Angel; Simonetti, Sara; Costa, Carlota; Gimenez-Capitan, Ana; Mendez, Pedro; Taron, Miguel; Rosell, Rafael (Elsevier, 2011-12)

The majority of non-small-cell lung cancer (NSCLC) patients present with locally advanced (35%) or metastatic disease (40%); in this setting, it is of the utmost importance to balance efficacy with toxicity. However, with ...
First clinical experience with a dedicated PET for hanging breast molecular imaging

Koolen, Bas; Aukema, T. S.; González Martínez, Antonio Javier; Vogel, W.; Caballero Ontanaya, Luis; Vrancken Peeters, Marie-Jeanne; Vroonland, Colinda; Rutgers, Emiel; Benlloch Baviera, Jose María; Valdés Olmos, Renato (Edizioni Minerva Medica, 2013-03)

[EN] Aim. Recently, a high-resolution dedicated PET system for hanging breast imaging (MAMMI PET) has been developed to improve primary tumor detection and characterization. The aim of this pilot study was to assess its ...
Increasing the Efficiency on Producing Radiology Reports for Breast Cancer Diagnosis by Means of Structured Reports

Segrelles Quilis, José Damián; Medina, Rosana; Blanquer Espert, Ignacio; Marti Bonmati, Luis (Schattauer, 2017-02-21)

Background: Radiology reports are commonly written on free-text using voice recognition devices. Structured reports (SR) have a high potential but they are usually considered more difficult to fill-in so their adoption in ...
Mobile devices to improve breast cancer information management

Segrelles Quilis, José Damián; Gimenez Fayos, Maite; Blanquer Espert, Ignacio (ERCIM EEIG, 2013-04)

[EN] Intuitive interfaces of mobile devices facilitate the introduction of structured data in breast cancer management, leading to an increase of completeness and accuracy of diagnosis and follow-up evaluations, as well ...
Modelo predictivo multiparamétrico del estatus axilar en pacientes con cáncer de mama: carga tumoral total y perfil molecular. Estudio multicéntrico

Bernet, Laia; Garcia-Gomez, Juan M; Cano Muñoz, Rafael; Piñero, Antonio; Ramírez, Ana Karina; Rodrigo, Maximiliano; Burgués, Octavi; Cámara de las Heras, Juan M. de la; Ruiz, Irene; Tormos, Bárbara (Elsevier, 2015)

[ES] [Objetivo] El objetivo de nuestro estudio es evaluar el impacto combinado de cada uno de los perfiles moleculares del cáncer de mama, subrogados inmunohistoquímicamente junto con la carga tumoral total del ganglio ...
Posttraumatic stress symptoms in breast cancer patients: Temporal evolution, predictors, and mediational models.

Perez, S; Galdon, MJ; Andreu, Y; Ibanez, E; Dura, E; Conchado Peiró, Andrea; Cardena, E (Wiley, 2014-04)

This longitudinal study (N = 102 women with nonmetastatic breast cancer) evaluated the time course of PTSD symptomatology (PTSDs) at different stages of cancer diagnosis and treatment: during treatment, at the end of ...