Vikingsson, Line Karina Alva; Gómez-Tejedor, José Antonio; Gallego Ferrer, Gloria; Gómez Ribelles, José Luís(Elsevier, 2015-05-01)
The aim of this experimental study is to predict the long-term mechanical behavior of a porous scaffold implanted in a cartilage defect for tissue engineering purpose. Fatigue studies were performed by up to 100,000 ...
Vikingsson, Line Karina Alva(Universitat Politècnica de València, 2015-07-29)
[EN] Abstract
The main purpose of this thesis is the design and characterization of an experimental articular cartilage model. The in vitro model is composed of a macro and micro- porous Polycaprolactone scaffold with ...
Vikingsson, Line Karina Alva; Gallego Ferrer, Gloria; Gómez-Tejedor, José Antonio; Gómez Ribelles, José Luís(Elsevier, 2014-04)
A model is proposed to assess mechanical behaviour of tissue engineering scaffolds and predict their performance in vivo during tissue regeneration. To simulate the growth of tissue inside the pores of the scaffold, the ...
Guerrero Calatayud, Carlos(Universitat Politècnica de València, 2018-10-17)
[ES] El objetivo del proyecto es investigar sistemas lipídicos simuladores de la membrana celular mediante sensores acústicos de alta frecuencia. Estos sensores darán información acerca de las propiedades nanomecánicas y ...
Vaqué Aura, Santiago(Universitat Politècnica de València, 2020-07-10)
[ES] Durante los últimos años, la necesidad de mejorar los modelos termodinámicos, haciéndolos más precisos y predecibles para sistemas complejos, ha aumentado. La complejidad de los sistemas electrolíticos se debe ...
Ivashchenko, Sergiy; Escobar Ivirico, Jorge Luis; García Cruz, Dunia Mercedes; Campillo Fernández, Alberto José; Gallego Ferrer, Gloria; Monleón Pradas, Manuel(SAGE Publications, 2015)
[EN] A series of novel poly(CLMA-co-HEA)/silica nanocomposites is synthesized from caprolactone 2-(methacryloyloxy)ethyl ester (CLMA) and 2-hydroxyethyl acrylate (HEA) as organic comonomers and the simultaneous sol-gel ...
Currently available keratoprosthesis models (nonbiological corneal substitutes) have a less than 75% graft survival rate at 2 years. We aimed at developing a model for keratoprosthesis based on the use of poly(ethyl acrylate) ...
[EN] Polymer ceramic composites obtained as the result of a mineralization process hold great promise for the future of tissue engineering. Simulated body fluids (SBFs) are widely used for the mineralization of polymer ...
Clara-Trujillo, Sandra; Marin-Paya, Juan Carlos; Cordón, Lourdes; Sempere, Amparo; Gallego Ferrer, Gloria; Gómez Ribelles, José Luís(Elsevier, 2019-05-01)
[EN] Stem cells reside in niches, specialized microenvironments that sustain and regulate their fate. Extracellular matrix (ECM), paracrine factors or other cells are key niche regulating elements. As the conventional 2D ...
Rogina, A.; Sandrk, N; Teruel Biosca, Laura; Antunovic, M.; Ivankovic, M.; Gallego Ferrer, Gloria(Croatian Society of Chemical Engineers/HDKI, 2019)
[EN] Bioactive synthetic hydrogels have emerged as promising materials because they can provide molecularly tailored biofunctions and adjustable mechanical properties. To mimic the mineralogical and organic components of ...
Vaca-González, J. J.; Escobar, J.F.; Guevara, J.M.; Hata, Y. A.; Gallego Ferrer, Gloria; Garzón-Alvarado, D. A.(Elsevier, 2019-04)
[EN] The growth plate is a cartilaginous layer present from the gestation period until the end of puberty where it ossifies joining diaphysis and epiphysis. During this period several endocrine, autocrine, and paracrine ...
Culebras Martínez, María(Universitat Politècnica de València, 2017-09-14)
[EN] Recent advances in tissue engineering have led to the development of polymer scaffolds
with suitable characteristics and properties capable of mimicking natural tissue and fulfilling the
different functions that the ...
García Briega, María Inmaculada(Universitat Politècnica de València, 2020-07-15)
[ES] El hueso es un tejido muy heterogéneo, por lo que crear una plataforma de cultivo que imite su entorno es un gran desafío. El hueso es un tejido piezoeléctrico y esta propiedad la producen las fibras de colágeno que ...
Luque Guillén, María Victoria(Universitat Politècnica de València, 2011-09-22)
El presente trabajo se centra en la fabricación y caracterización de una serie de materiales biodegradables basados en la fibrina. Dichos biomateriales han sido reticulados utilizando distintas concentraciones de genipin ...
[EN] The development of bioactive injectable system as cell carrier with minimal impact on viability of encapsulated cells represents a great challenge. In the present work, we propose a new pH-responsive chitosan-hydrox ...
Gilabert-Chirivella, Eduardo; Pérez-Feito, Ricardo; Ribeiro, Clarisse; Ribeiro, Sylvie; Correia, Daniela M.; González-Martín, Maria Luisa; Manero, Jose Maria; Lanceros-Mendez, S.; Ferrer, GG; Gómez Ribelles, José Luís(Elsevier, 2017-10)
[EN] Titanium and its alloys are widely used in medical implants because of their excellent properties. However, bacterial infection is a frequent cause of titanium-based implant failure and also compromises its osseointegration. ...
[EN] The aim of this study was to evaluate whether mechanical stimulation helps to modulate the redifferentiation of human chondrocytes on adhesive 3D substrates. In a previous work, it was shown that chondrocytes seeded ...
Composite scaffolds of poly(l-lactide acid) and hydroxyapatite are of great interest in bone tissue engineering, but their mechanical properties are typically inferior to scaffolds of pure poly(l-lactide acid) due to ...