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Listar por autor "Ferrando Monleón, Alejandro Ramón"

Mostrando ítems 1-20 de 21

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Aminopropyltransferases Involved in Polyamine Biosynthesis Localize Preferentially in the Nucleus of Plant Cells

Belda Palazón, Borja; RUIZ, L.; Martí Sanchis, Esmeralda; Tarraga Herrero, Susana; Tiburcio, A.; Culiañez Macia, Francisco Antonio; Farras, R.; Carrasco, P.; Ferrando Monleón, Alejandro Ramón (Public Library of Science, 2012-10)

Plant aminopropyltransferases consist of a group of enzymes that transfer aminopropyl groups derived from decarboxylated S-adenosyl-methionine (dcAdoMet or dcSAM) to propylamine acceptors to produce polyamines, ubiquitous ...
Biochemical quantitation of the eIF5A hypusination in Arabidopsis thaliana uncovers ABA-dependent regulation

Belda Palazón, Borja; Nohales Zafra, Maria Angeles; Rambla Nebot, Jose Luis; Aceña, José L.; Delgado, Oscar; Fustero Lardies, Santos; Martínez, M. Carmen; Granell Richart, Antonio; Carbonell Gisbert, Juan; Ferrando Monleón, Alejandro Ramón (Frontiers Media, 2014-05-16)

The eukaryotic translation elongation factor eIF5A is the only protein known to contain the unusual amino acid hypusine which is essential for its biological activity. This post-translational modification is achieved by ...
Caracterización funcional de modificaciones en residuos reguladores del factor de traducción eIF5A2 de A. thaliana

Antón Salvador, Javier (Universitat Politècnica de València, 2022-09-06)

[ES] El factor de iniciación de la traducción eucariótico eIF5A es una proteína altamente conservada en eucariotas con capacidad de unión a mRNAs, estando involucrada en la elongación de la traducción y que presenta una ...
Characterization of Arabidopsis Post-Glycosylphosphatidylinositol Attachment to Proteins Phospholipase 3 Like Genes

Bernat-Silvestre, Cesar; Ma, Yingxuan; Johnson, Kim; Ferrando Monleón, Alejandro Ramón; Aniento, Fernando; Marcote, María Jesús (Frontiers Media SA, 2022-02-11)

[EN] Lipid remodeling of Glycosylphosphatidylinositol (GPI) anchors is required for their maturation and may influence the localization and function of GPI-anchored proteins (GPI-APs). Maturation of GPI-anchors is well ...
Characterization of maize spermine synthase 1 (ZmSPMS1): evidence for dimerization and intracellular location

Maruri-López, I; Hernández-Sánchez, IE; Ferrando Monleón, Alejandro Ramón; Carbonell Gisbert, Juan; Jimenez-Bremont, JF (Elsevier, 2015-12)

[EN] Polyamines are ubiquitous positively charged metabolites that play an important role in wide fundamental cellular processes; because of their importance, the homeostasis of these amines is tightly regulated. Spermine ...
Citrus exocortis viroid causes ribosomal stress in tomato plants

Cottilli, Patrick; Belda-Palazón, Borja; Adkar-Purushothama, Charith Raj; Perreault, Jean-Pierre; Schleiff, Enrico; Rodrigo Bravo, Ismael; Ferrando Monleón, Alejandro Ramón; Lisón, Purificación (Oxford University Press, 2019-09-19)

[EN] Viroids are naked RNAs that do not code for any known protein and yet are able to infect plants causing severe diseases. Because of their RNA nature, many studies have focused on the involvement of viroids in RNA-mediated ...
Estudios funcionales de las modificaciones post-traduccionales del factor de traducción eIF5A2 de Arabidopsis thaliana

Ivars Lanàquera, Elia (Universitat Politècnica de València, 2021-07-30)

[ES] El factor de traducción eIF5A es una proteína cuyas funciones a día de hoy no están completamente definidas. Es la única proteína conocida que sufre el proceso de hipusinación, una modificación post-traduccional ...
Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity

Martínez-Férriz, Arantxa; Gandía, Carolina; Pardo-Sánchez, José Miguel; Fathinajafabadi, Alihamze; Ferrando Monleón, Alejandro Ramón; Farras, Rosa (BioMed Central, 2023-03-13)

[EN] Background Eukaryotic Initiation Factor 5A (eIF-5A), an essential translation factor, is post-translationally activated by the polyamine spermidine. Two human genes encode eIF-5A, being eIF5-A1 constitutively expressed ...
Extremophiles as Plant Probiotics to Promote Germination and Alleviate Salt Stress in Soybean

Santos, Ana P.; Belfiore, Carolina; Urbez Lagunas, Cristina; Ferrando Monleón, Alejandro Ramón; BLAZQUEZ RODRIGUEZ, MIGUEL ANGEL; Farías, María E. (Springer-Verlag, 2023-02)

[EN] Bacteria isolated from extreme environments have been shown to promote plant growth under challenging conditions. This study aimed to examine the performance of the extremophilic microorganisms under salt stress and ...
Extremophilic bacteria restrict the growth of Macrophomina phaseolina by combined secretion of polyamines and lytic enzymes

Santos, Anna P.; Nieva Muratore, Luciana; Sole-Gil, Anna; Farías, María E.; Ferrando Monleón, Alejandro Ramón; BLAZQUEZ RODRIGUEZ, MIGUEL ANGEL; Belfiore, Carolina (Springer-Verlag, 2021-09-15)

[EN] Extremophilic microorganisms were screened as biocontrol agents against two strains of Macrophomina phaseolina (Mp02 and 06). Stenotrophomonas sp. AG3 and Exiguobacterium sp. S58 exhibited a potential in vitro antifungal ...
Fertility and Polarized Cell Growth Depends on eIF5A for Translation of Polyproline-Rich Formins in Saccharomyces cerevisiae

Li, Tianlu; Belda Palazón, Borja; Ferrando Monleón, Alejandro Ramón; Alepuz, Paula (Genetics Society of America, 2014-08)

eIF5A is an essential and evolutionary conserved translation elongation factor, which has recently been proposed to be required for the translation of proteins with consecutive prolines. The binding of eIF5A to ribosomes ...
Funciones de las poliaminas en procesos de autofagia vegetal

Malonda Costa, Safir (Universitat Politècnica de València, 2020-02-12)

[ES] El proceso de autofagia, que permite la auto-renovación de elementos celulares dañados, está bien documentado tanto en levadura como en células animales, si bien su caracterización en células vegetales está en sus ...
Hipusinación del factor de traducción eIF5A dependiente de poliaminas

Belda Palazón, Borja (Universitat Politècnica de València, 2015-03-30)

RESUMEN La hipusinación es una modificación post-traduccional dependiente de espermidina que activa al factor de traducción eIF5A, y que es esencial en todos los eucariotas. En los últimos años se ha sugerido un importante ...
Interacciones entre eIF5A y ACL5 en el desarrollo del xilema en Arabidopsis thaliana

ALMENDÁRIZ PALACIOS, CARLA (Universitat Politècnica de València, 2015-02-23)

[EN] The acl5 mutation produces opposite alerations to DHS inactivation during xylem differentiation and maturation. There is a mutual complementation between the two loss of function during development of xylem. eIF5A ...
Mecanismos de toxicidad de poliaminas: inhibición del recambio de proteínas

Sayas Montañana, Enric Miquel (Universitat Politècnica de València, 2014-06-13)

Las poliaminas son pequeñas moléculas de naturaleza policatiónica que se encuentran de manera natural todos los organismos estudiados. Estas sustancias son esenciales para el crecimiento de los organismos, no obstante, a ...
Nuclear localization of the dehydrin OpsDHN1 is determined by histidine-rich domain

Hernández-Sánchez, IE; Maruri-López, I; Ferrando Monleón, Alejandro Ramón; Carbonell Gisbert, Juan; Graether, SP; Jimenez-Bremont, JF (Frontiers Media, 2015-09-07)

The cactus OpsDHN1 dehydrin belongs to a large family of disordered and highly hydrophilic proteins known as Late Embryogenesis Abundant (LEA) proteins, which accumulate during the late stages of embryogenesis and in ...
Polyamines as Quality Control Metabolites Operating at the Post-Transcriptional Level

Poidevin, Laetitia; Unal, Dilek; Belda-Palazón, Borja; Ferrando Monleón, Alejandro Ramón (MDPI, 2019-04)

[EN] Plant polyamines (PAs) have been assigned a large number of physiological functions with unknown molecular mechanisms in many cases. Among the most abundant and studied polyamines, two of them, namely spermidine (Spd) ...
Polyamines interfere with protein ubiquitylation and cause depletion of intracellular amino acids: a possible mechanism for cell growth inhibition

Sayas Montañana, Enric Miquel; Pérez-Benavente, Beatriz; Manzano, C.; Farràs, Rosa; Alejandro Martinez, Santiago; del Pozo, J.C.; Ferrando Monleón, Alejandro Ramón; Serrano Salom, Ramón (John Wiley & Sons, 2019-01-28)

[EN] Spermidine is a polyamine present in eukaryotes with essential functions in protein synthesis. At high concentrations spermidine and norspermidine inhibit growth by unknown mechanisms. Transcriptomic analysis of the ...
Regulation of translation initiation under biotic and abiotic stresses

Echevarria-Zomeno, Sira; Yanguez, Emilio; Fernandez-Bautista, Nuria; Castro-Sanz, Ana B.; Ferrando Monleón, Alejandro Ramón; Castellano, M. Mar (MDPI, 2013-03)

[EN] Plants have developed versatile strategies to deal with the great variety of challenging conditions they are exposed to. Among them, the regulation of translation is a common target to finely modulate gene expression ...
Relevance of the Axis Spermidine/eIF5A for Plant Growth and Development

Belda Palazón, Borja; Almendáriz, Carla; Martí Sanchis, Esmeralda; Carbonell Gisbert, Juan; Ferrando Monleón, Alejandro Ramón (Frontiers Media, 2016-03-02)

One key role of the essential polyamine spermidine in eukaryotes is to provide the 4-aminobutyl moiety group destined to the post-translational modification of a lysine in the highly conserved translation factor eIF5A. ...