Bailach Adsuara, Anna(Universitat Politècnica de València, 2017-09-05)
[EN] In recent years, progress in new technologies has resulted in the capacity to
generate massive amounts of data, this is known as the "Omics Age". The challenge now is
data integration and analysis. Thus, Systems ...
Chevilly-Tena, Sergio; Dolz-Edo, Laura; López-Nicolás, José M.; Morcillo, Luna; Vilagrosa, Alberto; Yenush, Lynne; Mulet, José Miguel(American Chemical Society, 2021-09-08)
[EN] Broccoli is a cruciferous crop rich in health-promoting metabolites. Due to several factors, including anthropogenic global warming, aridity is increasing in many cultivation areas. There is a great demand to characterize ...
[EN] As the proper maintenance of intracellular potassium and sodium concentrations
is vital for cell growth, all living organisms have developed a cohort
of strategies to maintain proper monovalent cation homeostasis. ...
The intrinsic ability of cells to adapt to a wide range of environmental conditions is a fundamental process required for survival. Potassium is the most abundant cation in living cells and is required for essential cellular ...
Para separar las proteínas presentes en una muestra por electroforesis en un gel de poliacrilamida, una vez tengamos montado el sistema en el que polimerizar el gel, prepararemos el mismo, tal y como se detalla en este vídeo.
For the separation of proteins by electrophoresis in polyacrylamide gel, once the system where to polymerize the gel is already assembled, the gel will be prepared, as explained in this video.
Roig Soucase, Sergio(Universitat Politècnica de València, 2020-09-07)
[ES] Saccharomyces cerevisiae es ampliamente utilizada como modelo eucariota debido a su rápido crecimiento y alto grado de conservación con respecto a los mamíferos. El modo de crecimiento vegetativo más común en S. ...
Cabal Blanco, Irene(Universitat Politècnica de València, 2018-09-20)
[EN] Transient gene expression via Agrobacterium-mediated DNA transfer is a simple, rapid, versatile and economic technique widely used for the study of gene function, protein localization, protein-protein interaction and ...
González García, Ana María(Universitat Politècnica de València, 2015-10-21)
[ES] El objetivo del proyecto es estudiar y comprender el control de la expresión génica en células eucariotas en situaciones de estrés. La traducción es un complejo proceso que requiere un amplio número de factores para ...
Primo Planta, Cecilia; Ferri-Blazquez, Alba; Loewith, Robbie; Yenush, Lynne(American Society for Biochemistry and Molecular Biology, 2017)
[EN] The proper maintenance of potassium homeostasis is crucial for cell viability. Among the major determinants of potassium uptake in the model organism Saccharomyces cerevisiae are the Trk1 high affinity potassium ...
Primo Planta, Cecilia(Universitat Politècnica de València, 2012-05-15)
Las proteínas quinasa identificadas en Saccharomyces cerevisiae Sat4/Hal4 y Hal5 son necesarias para la estabilidad del transportador de K+ y algunas permeasas de aminoácidos y de glucosa. El análisis transcriptómico de ...
[EN] Regulated expression of the Ena1 Na+-ATPase is a crucial event for adaptation to high
salt and/or alkaline pH stress in the budding yeast Saccharomyces cerevisiae. ENA1
expression is under the control of diverse ...
Llopis Torregrosa, Vicent; Ferri-Blazquez, Alba; Adam-Artigues, Anna; Deffontaines, Emilie; van Heusden, G. Paul H.; Yenush, Lynne(American Society for Biochemistry and Molecular Biology, 2016)
[EN] Cell viability requires adaptation to changing environmental conditions. Ubiquitin-mediated endocytosis plays a crucial role in this process, because it provides a mechanism to remove transport proteins from the ...
Martínez Fernández de la Cámara, Cristina Isabel(Universitat Politècnica de València, 2014-10-30)
[EN] Retinitis Pigmentosa (RP) is a common form of hereditary retinal degeneration characterized by the loss of retinal photoreceptor cells (rods and cones) and constitutes the largest single cause of blindness in the ...
Ruiz Espí, Diego(Universitat Politècnica de València, 2021-07-16)
[EN] PD is a multifactorial pathology characterized by both motor and non-motor features;
its development seems to be mainly linked to the formation of αSyn aggregates and their
accumulation in dopaminergic neurons. αSyn ...
[EN] We have identified QDR2 in a screening for genes able to confer tolerance to sodium and/or lithium stress upon overexpression. Qdr2 is a multidrug transporter of the major facilitator superfamily, originally described ...
Locascio, Antonella Anna Maria; Andrés-Colás, Nuria; Mulet, José Miguel; Yenush, Lynne(MDPI AG, 2019-05-01)
[EN] Sodium and potassium are two alkali cations abundant in the biosphere. Potassium is essential for plants and its concentration must be maintained at approximately 150 mM in the plant cell cytoplasm including under ...
López-Gresa, María Pilar; Lisón, Purificación; Yenush, Lynne; Conejero Tomás, Vicente; Rodrigo Bravo, Ismael; Belles Albert, José Mª(Public Library of Science, 2016)
[EN] Tomato plants expressing the NahG transgene, which prevents accumulation of endogenous salicylic acid (SA), were used to study the importance of the SA signalling pathway in basal defence against Citrus Exocortis ...
Casado García-Consuegra, Zulema(Universitat Politècnica de València, 2021-10-07)
[ES] En los últimos años, la aparición de bacterias resistentes a los antibióticos se ha convertido en una amenaza mundial debido al mal uso y abuso de estas sustancias en el tratamiento de enfermedades animales y humanas. ...
Sáez García, Zara(Universitat Politècnica de València, 2015-10-16)
[EN] Neuroblastoma is the most common extracranial solid tumor in in infants, which originates from
primordial neural crest cells that migrate in the embryo to form sympathetic ganglions and adrenal
RESUMEN medulla. ...