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Browsing by UPV Unit "Universitat Politècnica de València. Centro de Investigación e Innovación en Bioingeniería - Centre de Recerca i Innovació en Bioenginyeria"

Now showing items 1-11 of 11

Analysis of the response of human iPSC-derived cardiomyocyte tissue to I CaL block. A combined in vitro and in silico approach

Dasí, Albert; Hernández-Romero, Ismael; Gómez, Juan F.; Climent, Andreu M.; Ferrero De Loma-Osorio, José María; Trenor Gomis, Beatriz Ana (Elsevier, 2021-10)

[EN] The high incidence of cardiac arrythmias underlines the need for the assessment of pharmacological therapies. In this field of drug efficacy, as in the field of drug safety highlighted by the Comprehensive in Vitro ...
Analysis of vulnerability to reentry in acute myocardial ischemia using a realistic human heart model

Carpio, Edison F.; Gómez, Juan F.; Rodríguez-Matas, José F.; Trenor Gomis, Beatriz Ana; Ferrero De Loma-Osorio, José María (Elsevier, 2022-02)

[EN] Electrophysiological alterations of the myocardium caused by acute ischemia constitute a pro-arrhythmic substrate for the generation of potentially lethal arrhythmias. Experimental evidence has shown that the ...
Análisis sobre la implantación del sistema de autoseguro de accidentes de trabajo y enfermedades profesionales en la Universitat Politècnica de València

Garcia Cervera, Manuel (Universitat Politècnica de València, 2014-02-07)

[ES] Este Trabajo Final de Carrera (TFC) consiste en la realización de un Análisis sobre la implantación del sistema de autoseguro de accidentes de trabajo y enfermedades profesionales en la Universitat Politècnica De ...
Análisis y elaboración de un plan de mejoras en materia de salud en una empresa constructora

Martínez Briz, Miriam (Universitat Politècnica de València, 2013-04-23)

[ES] La siniestralidad laboral y el absentismo es un problema importante que tienen las empresas españolas y europeas debido a las altas cifras que se han generado, lo que ocasiona un alto coste económico, social y sobre ...
Application of Machine Learning to improve the efficiency of electrophysiological simulations used for the prediction of drug-induced ventricular arrhythmia

Rodríguez-Belenguer, Pablo; Kopańska, Karolina; Llopis Lorente, Jordi; Trénor Gomis, Beatriz Ana; Saiz Rodríguez, Francisco Javier; Pastor, Manuel (Universitat Politècnica de València, 2022-06-03)

In cardiotoxicity studies it is common to pre-compute the values of different biomarkers (my equation or TX) for a range of ion channel blockades. Since every simulation requires costly computations, to complete the matrix ...
Characterization of Atrial Propagation Patterns and Fibrotic Substrate With a Modified Omnipolar Electrogram Strategy in Multi-Electrode Arrays

Riccio, Jennifer; Alcaine, Alejandro; Rocher-Ventura, Sara; Martínez-Mateu, Laura; Laranjo, Sergio; Saiz Rodríguez, Francisco Javier; Laguna, Pablo; Martínez, Juan Pablo (Frontiers Media SA, 2021-09-03)

[EN] Introduction: The omnipolar electrogram method was recently proposed to try to generate orientation-independent electrograms. It estimates the electric field from the bipolar electrograms of a clique, under the ...
Computational simulations of the effects of the V17M missense mutation on atrial electrical activity

Belletti, Rebecca; Martínez Mateu, L.; Romero Pérez, Lucia; Saiz Rodríguez, Francisco Javier (Grupo de Técnicas Ópticas Aplicadas, Universidad de Cantabria, 2019-11-29)

[EN] Atrial fibrillation is a cardiac arrhythmia responsible for disorganized electrical activity of the upper chambers of the heart. Recently genetic mutations have been associated to episodes of atrial fibrillation in ...
Considering Population Variability of Electrophysiological Models Improves the In Silico Assessment of Drug-Induced Torsadogenic Risk

Llopis Lorente, Jordi; Trénor Gomis, Beatriz Ana; Saiz Rodríguez, Francisco Javier (2022-05-13)

This repository contains the parameter sets of the population of TorORd models and the the population of ORdmD models, the ORdmD CellML file and MALTAB code used in Llopis-Lorente, J., Trenor, B., Saiz, J. (2022). Considering ...
Fomentando el aprendizaje autorregulado en la asignatura Conversión y Procesado de la Energía mediante la incorporación de los ODS a sus contenidos

Fernández Díaz, Román; Jimenez Jimenez, Yolanda; Hernández Ferrer, Alberto; Arnau Vives, Antonio (Editorial Universitat Politècnica de València, 2022-10-28)

[EN] According to empirical evidence, those students who present a Self-Regulated Learning (SRL) pattern are more likely to achieve academic success. This pattern is characterized by the fact that students control their ...
In vivo development of tissue engineered vascular grafts: a fluid-solid-growth model

Latorre, Marcos; Szafron, Jason M.; Ramachandra, Abhay B.; Humphrey, Jay D. (Springer-Verlag, 2022-02-18)

[EN] Methods of tissue engineering continue to advance, and multiple clinical trials are underway evaluating tissue engineered vascular grafts (TEVGs). Whereas initial concerns focused on suture retention and burst pressure, ...
Uncertainty Assessment of Proarrhythmia Predictions Derived from Multi-Level in Silico Models

Kopanska, Karolina; Rodríguez-Belenguer, Pablo; Llopis-Lorente, Jordi; Trénor, Beatriz; Saiz, Javier; Pastor, Manuel (Universitat Politècnica de València, 2023-02-14)

[EN] These datasets were generated to train ("PopulationDrugsTrainingKrNaLCaL.xlsx") and test ("PopulationDrugsTestKrCaLNaL.xlsx") the uncertainty assessment models developed in the paper "Uncertainty assessment of ...